Three-dimensional time-resolved optical mammography of the uncompressed breast

Optical tomography is being developed as a means of detecting and specifying disease in the adult female breast. We present a series of clinical three-dimensional optical images obtained with a 32-channel time-resolved system and a liquid-coupled interface. Patients place their breasts in a hemispherical cup to which sources and detectors are coupled, and the remaining space is filled with a highly scattering fluid. A cohort of 38 patients has been scanned, with a variety of benign and malignant lesions. Images show that hypervascularization associated with tumors provides very high contrast due to increased absorption by hemoglobin. Only half of the fibroadenomas scanned could be observed, but of those that could be detected, all but one revealed an apparent increase in blood volume and a decrease in scatter and oxygen saturation.     

Effects of interference and cognitive arousal upon the processing of organized thought.

Reports part of a series dealing with cognitive arousal and reverberation. Prior investigations highlighted the influence of brief posthypnotic manipulations of mental arousal, introduced during the reverberation phase following stimulus presentation of strings of consonants, upon the later salience of those stimuli. 2 male undergraduates' tasks consisted 1st of reading aloud 6 words in scrambled order from 2 familiar 3-word phrases and then reporting whatever words popped into mind during a 12-sec period. Posthypnotic experimental interventions consisted of (1) the auditory hallucination of numbers while reporting words, and (2) the alterations of cognitive arousal in 5 degrees ranging from very high to very low. Both variables produced significant effects upon the meaningful organization of words in 2 Ss' reports. (PsycINFO Database Record (c) 2010 APA, all rights reserved)