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31.
The Medical and Pharmaceutical industries have shown high interest in the precise engineering of protein hormones and enzymes that perform existing functions under a wide range of conditions. Proteins are responsible for the execution of different functions in the cell: catalysis in chemical reactions, transport and storage, regulation and recognition control. Computational Protein Design (CPD) investigates the relationship between 3-D structures of proteins and amino acid sequences and looks for all sequences that will fold into such 3-D structure. Many computational methods and algorithms have been proposed over the last years, but the problem still remains a challenge for Mathematicians, Computer Scientists, Bioinformaticians and Structural Biologists. In this article we present a new method for the protein design problem. Clustering techniques and a Dead-End-Elimination algorithm are combined with a SAT problem representation of the CPD problem in order to design the amino acid sequences. The obtained results illustrate the accuracy of the proposed method, suggesting that integrated Artificial Intelligence techniques are useful tools to solve such an intricate problem.  相似文献   
32.
In the last decade, bio-inspired self-organising mechanisms have been applied to different domains, achieving results beyond traditional approaches. However, researchers usually use these mechanisms in an ad-hoc manner. In this way, their interpretation, definition, boundary (i.e. when one mechanism stops, and when another starts), and implementation typically vary in the existing literature, thus preventing these mechanisms from being applied clearly and systematically to solve recurrent problems. To ease engineering of artificial bio-inspired systems, this paper describes a catalogue of bio-inspired mechanisms in terms of modular and reusable design patterns organised into different layers. This catalogue uniformly frames and classifies a variety of different patterns. Additionally, this paper places the design patterns inside existing self-organising methodologies and hints for selecting and using a design pattern.  相似文献   
33.
In an operational environment, the identification and reproduction of faults may be hard to be done, specially in complex systems. Use of fault injection accelerates this process, improving the test of fault tolerance mechanisms. However, there are a significant amount of fault injectors available, using several different approaches. This diversity of tools, each one with different methods to describe faultloads for fault injection campaigns, imposes severe obstacles to the efficient use of such fault injectors. In this context, this paper presents jFaultload, which applies Java for the specification of faultloads and translates them to specific formats that are appropriate to each available fault injector. Fault injectors for communication systems were integrated in the environment and completes the test scenario. The service under test used to demonstrate the usability and expressiveness of our solution is a video streaming session using RTP Protocol.  相似文献   
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六开关三相四线PWM整流器拓扑是适合于中大功率高频UPS装置的前级整流器拓扑.与常规的六开关三相三线整流器相比,三相四线整流器输出正负直流母线,并且输入侧存在零序电流通路,如果沿用三相三线整流器的控制方法,必然会引起很大的中线电流.针对此问题.讨论了三相四线PWM整流器输出为正负直流母线电压均衡控制和中线电流控制问题,建立了三相四线整流器数学模型,分析了中线电流产生的机理以及抑制的方法,设计了基于同步旋转坐标系的三相四线整流器的控制算法.在功率40kW的实验样机上验证了控制方法的有效性,保证了输出正负母线电压的平衡及较小的输入电流谐波.  相似文献   
36.
Brock.  U Salaz.  T 《电子产品世界》2000,(8):35-36,47
本文主要讨论在RS-485网络设计中,如何在保持良好的传输特性的同时降低率损耗。  相似文献   
37.
The production of high critical current density Jc Bi-2223/Ag sheathed conductors is a complex process involving interactions among many different parameters. The effects of three factors: 1) powder production path, 2) the first sinter temperature, and 3) the subsequent sinter temperatures were investigated. Statistical methods were used to design the experiment and interpret the results. Transport Jc was the main response for the analysis, but microstructural results were also used to assess the physical basis for the differences in performance. The powder variable had the largest main effect with only very weak main effects for the other factors.  相似文献   
38.
IR与RS-232的匹配技术   总被引:2,自引:0,他引:2  
现代电子设备通常包含最新的数据通信接口,以实现更高的数据率或增进用户的便利性。红外技术(IR)是数据通信接口的一个很好例子,但有时单独使用这种最新接口还是不够的,设备还需要与采用传统接口如RS-232的老设备兼容才会被用户所接受。因此,常见的红外技术和RS-232共存于同一设备中。  相似文献   
39.
The prime characteristic of spread spectrum modulated signals is that their bandwidth is greater than the information rate. In this way a redundancy is introduced that allows the severe levels of inteference inherent in the transmission of digital information over radio and satellite links to be overcome. Current spread spectrum applications are primarily in military communications; nevertheless, there is growing interest in this technique for third generation mobile radio networks (UMTS, FPLTS, etc.) with open discussion regarding the practicality of using a multiple access system based on spread spectrum techniques (CDMA). However, in order to support as many users in the same bandwidth as other multiple access techniques such as TDMA or FDMA, it is important how to generate large families of sequences that present low cross-correlation. The aim of this paper is to describe a spreading codes generator that can produce a large number of PN sequences with good properties of auto- and cross-correlation. Moreover, the codes generated shows high unpredictability and good statistical behaviour. This also allows the implementation of some features that are common on military networks such as message privacy (increasingly important in commercial networks) without additional cost. The structure presented shows itself to be advantageous for high speed generation of codes at a low cost, low power consumption (allowing longer life for batteries), small size and simplicity of implementation, essential ingredients for commercial equipment. Another attractive feature is its structural parallelism, useful in VLSI implementations. All of these features render it potentially suitable for the implementation of channel bandwidth sharing systems in future wireless personal communications networks.  相似文献   
40.
Prediction of transient natural convection heat transfer in vented enclosures has multiple applications such as understanding of cooking environment in ovens and heat sink performance in electronic packaging industry. The thermal field within an oven has significant impact on quality of cooked food and reliable predictions are important for robust design and performance evaluation of an oven. The CFD modeling of electric oven involves three-dimensional, unsteady, natural convective flow-thermal field coupled with radiative heat transfer. However, numerical solution of natural convection in enclosures with openings at top and bottom (ovens) can often lead to non-physical solutions such as reverse flow at the top vent, partly a function of initialization and sometimes dependent on boundary conditions. In this paper, development of a physics based robust CFD methodology is discussed. This model has been developed with rigorous experimental support and transient validation of this model with experiments show less than 3% discrepancy for a bake cycle. There is greater challenge in simulating a broil cycle, where the fluid inside the cavity is stably stratified and is also highlighted. A comparative analyses of bake and broil cycle thermal fields inside the oven are also presented.  相似文献   
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