Statistical evaluation of the lateral-torsional buckling resistance of steel I-beams, Part 1: Variability of the Eurocode 3 resistance model

The EN version of part 1-1 of EC3 introduces significant changes in the evaluation of the lateral-torsional buckling resistance of unrestrained beams, as well as alternative design procedures. Simultaneously, as a part of the preparation of the National Annexes of EC3 part 1-1 and the establishment of the corresponding NDP’s (Nationally Determined Parameters) it becomes necessary to define the partial safety coefficients for the bending resistance of beams when lateral-torsional buckling is a potential failure mode. In this paper the methodology for the resistance evaluation of beams subjected to instability is briefly described and the results are compared with FEM numerical results for the same elements. Subsequently, to assess the accuracy of the alternative design formulae, a statistical analysis of the results is performed on the basis of EN 1990-Annex D. A methodology is proposed for the evaluation of the design procedures allowing for the uncertainties in the resistance model. Results are presented for a wide set of beam geometries and loading cases and a proposal for the definition of the partial safety factor γ_rd is presented for the various methods, in line with the target failure probability of EN 1990.     

Consumers’ quality perception of national branded, national store branded, and imported store branded beef

This study investigated the differences in the consumers’ quality perception of national branded, national store branded, and imported store branded beef. Partial Least Squares analysis is used for modelling the quality perception process. Results show that consumers perceived national branded Carnalentejana beef, as better on all quality cues and quality aspects than the other two store branded beefs. Preference for Carnalentejana beef stayed highly consistent even after the blind test, where consumers differentiated this beef from the other two beef brands on all sensory dimensions: taste, tenderness, and juiciness, and chose it as the preferred one. Consumers utilized more perceived intrinsic cues to infer expected eating quality of store branded beefs.     

Abiotic Stress Response of Near-Isogenic Spring Durum Wheat Lines under Different Sowing Densities

A detailed study was made of changes in the plant development, morphology, physiology and yield biology of near-isogenic lines of spring durum wheat sown in the field with different plant densities in two consecutive years (2013–2014). An analysis was made of the drought tolerance of isogenic lines selected for yield QTLs (QYld.idw-2B and QYld.idw-3B), and the presence of QTL effects was examined in spring sowings. Comparisons were made of the traits of the isogenic pairs QYld.idw-3B++ and QYld.idw-3B−− both within and between the pairs. Changes in the polyamine content, antioxidant enzyme activity, chlorophyll content of the flag leaf and the normalized difference vegetation index (NDVI) of the plot were monitored in response to drought stress, and the relationship between these components and the yield was analyzed. In the case of moderate stress, differences between the NIL++ and NIL−− pairs appeared in the early dough stage, indicating that the QYld.idw-3B++ QTL region was able to maintain photosynthetic activity for a longer period, resulting in greater grain number and grain weight at the end of the growing period. The chlorophyll content of the flag leaf in phenophases Z77 and Z83 was significantly correlated with the grain number and grain weight of the main spike. The grain yield was greatly influenced by the treatment, while the genotype had a significant effect on the thousand-kernel weight and on the grain number and grain weight of the main spike. When the lines were compared in the non-irrigated treatment, significantly more grains and significantly higher grain weight were observed in the main spike in NIL++ lines, confirming the theory that the higher yields of the QYld.idw-3B++ lines when sown in spring and exposed to drought stress could be attributed to the positive effect of the “Kofa” QTL on chromosome 3B.     

Zebrafish as a Model for the Study of Lipid-Lowering Drug-Induced Myopathies

Drug-induced myopathies are classified as acquired myopathies caused by exogenous factors. These pathological conditions develop in patients without muscle disease and are triggered by a variety of medicaments, including lipid-lowering drugs (LLDs) such as statins, fibrates, and ezetimibe. Here we summarise the current knowledge gained via studies conducted using various models, such as cell lines and mammalian models, and compare them with the results obtained in zebrafish (Danio rerio) studies. Zebrafish have proven to be an excellent research tool for studying dyslipidaemias as a model of these pathological conditions. This system enables in-vivo characterization of drug and gene candidates to further the understanding of disease aetiology and develop new therapeutic strategies. Our review also considers important environmental issues arising from the indiscriminate use of LLDs worldwide. The widespread use and importance of drugs such as statins and fibrates justify the need for the meticulous study of their mechanism of action and the side effects they cause.     

Fractional Jacobi Galerkin spectral schemes for multi-dimensional time fractional advection–diffusion–reaction equations

One of the ongoing issues with time fractional diffusion models is the design of efficient high-order numerical schemes for the solutions of limited regularity. We construct in this paper two efficient Galerkin spectral algorithms for solving multi-dimensional time fractional advection–diffusion–reaction equations with constant and variable coefficients. The model solution is discretized in time with a spectral expansion of fractional-order Jacobi orthogonal functions. For the space discretization, the proposed schemes accommodate high-order Jacobi Galerkin spectral discretization. The numerical schemes do not require imposition of artificial smoothness assumptions in time direction as is required for most methods based on polynomial interpolation. We illustrate the flexibility of the algorithms by comparing the standard Jacobi and the fractional Jacobi spectral methods for three numerical examples. The numerical results indicate that the global character of the fractional Jacobi functions makes them well-suited to time fractional diffusion equations because they naturally take the irregular behavior of the solution into account and thus preserve the singularity of the solution.

     

Antimicrobial properties of 1‐monoacylglycerols prepared from undecanoic (C11:0) and undecenoic (C11:1) acid

Antimicrobial activity of monoacylglycerols (MAG) with odd number of carbons prepared from undecanoic (MAG C11:0) and undecenoic (MAG C11:1) was investigated. Data showed that both studied substances successfully inhibited Gram‐positive cocci (Staphylococcus aureus) and spore‐forming rods (Bacillus cereus). Gram‐negative bacteria were highly resistant against MAG C11:0 and showed considerable tolerance against MAG C11:1. Minimum inhibitory concentration (MIC) of MAG C11:1 was possible to determine for Escherichia coli only. Complete inhibition of three fungi genera (Alternaria, Cladosporium, Trichothecium) was achieved using MAG C11:1 with a concentration higher than 750 µg/mL. The growth of Aspergillus niger, Mucor racemosus, Phoma, Scopulariopsis, Trichoderma was significantly reduced. Generally, MAG C11:1 was more efficient than MAG C11:0 against all tested microorganisms. Due to a rich production of degradation enzymes, some fungi species surprisingly adapted their metabolism during growth and were even able to utilise tested MAG as a source of carbon. Practical applications: MAG composed of fatty acids with odd number of carbons in molecule are a promising group of substances applicable in food industry and cosmetics. They represent materials with broad spectrum of antimicrobial activity, especially against Gram‐positive bacteria. More efficient MAG C11:1 with a double bond in molecule can be recommended for reduction of S. aureus that cause food enterotoxicosis.     

Advanced performance evaluation of a reverse osmosis treatment for oilfield produced water aiming reuse

Technology advancements and the increasing need for fresh water resources have created the potential for desalination of oil field brine (produced water) to be a cost-effective fresh water resource for beneficial reuse. At the mature oil and gas production areas in the northeast of Brazil, the majority of wells produce a substantial amount of water in comparison with oil production (more than 90%). At these fields, the produced water has to be treated on site only for oil and solids removal aiming re-injection. The aim of this work is to assess the quality of the produced water stream after a reverse osmosis desalination process in terms of physicochemical characteristics influencing reuse of the water for irrigation or other beneficial uses.