基于ARM的机载火控雷达元器件自动化检测技术研究

为解决传统技术针对机载火控雷达元器件检测吞吐率低的问题,设计基于ARM的机载火控雷达元器件自动化检测技术。确定机载火控雷达元器件自动化检测特征,基于ARM响应曲线拟合机载火控雷达元器件检测数据,表达其自动化检测特征属性值,以此实现机载火控雷达元器件自动化检测。设计实例分析,结果表明,设计检测技术检测吞吐率均在3reqs/s以上,对比传统手段具有明显的优势,能够解决传统检测技术检测吞吐率低的问题。     

Surface activation of colloidal indium phosphide nanocrystals

Against general wisdom in crystallization,the nucleation of InP and Ⅲ-Ⅴ quantum dots (QDs) often dominates their growth.Systematic studies on InP QDs identified the key reason for this:the dense and tight alkanoate-ligand shell around each nanocrystal.Different strategies were explored to enable necessary ligand dynamics—i.e.,ligands rapidly switching between being bonded to and detached from a nanocrystal upon thermal agitation—on nanocrystals to simultaneously retain colloidal stability and allow appreciable growth.Among all the surface-activation reagents tested,2,4-diketones (such as acetylacetone) allowed the full growth of InP QDs with indium alkanoates and trimethylsilylphosphine as precursors.While small fatty acids (such as acetic acid) were partially active,common neutral ligands (such as fatty amines,organophosphines,and phosphine oxides) showed limited activation effects.The existing amine-based synthesis of InP QDs was activated by acetic acid formed in situ.Surface activation with common precursors enabled the growth of InP QDs with a distinguishable absorption peak between ～450 and 650 nm at mild temperatures (140-180 ℃).Furthermore,surface activation was generally applicable for InAs and Ⅲ-Ⅴ based core/shell QDs.     

The influence of bile salts on the distribution of simvastatin in the octanol/buffer system

Abstract

Introduction: Distribution coefficient (D) is useful parameter for evaluating drugs permeability properties across biological membranes, which are of importance for drugs bioavailability. Given that bile acids are intensively studied as drug permeation-modifying and -solubilizing agents, the aim of this study was to estimate the influence of sodium salts of cholic (CA), deoxycholic (DCA) and 12-monoketocholic acids (MKC) on distribution coefficient of simvastatin (SV) (lactone [SVL] and acid form [SVA]) which is a highly lipophilic compound with extremely low water solubility and bioavailability.

Methods: LogD values of SVA and SVL with or without bile salts were measured by liquid–liquid extraction in n-octanol/buffer systems at pH 5 and 7.4. SV concentrations in aqueous phase were determined by HPLC-DAD. Chem3D Ultra program was applied for computation of physico-chemical properties of analyzed compounds and their complexes.

Results: Statistically significant decrease in both SVA and SVL logD was observed for all three studied bile salts at both selected pH. MKC exerted the most pronounced effect in the case of SVA while there were no statistically significant differences between observed bile salts for SVL. The calculated physico-chemical properties of analyzed compounds and their complexes supported experimental results.

Conclusions: Our data indicate that the addition of bile salts into the n-octanol/buffer system decreases the values of SV distribution coefficient at both studied pH values. This may be the result of the formation of hydrophilic complexes increasing the solubility of SV that could consequently impact the pharmacokinetic parameters of SV and the final drug response in patients.     

短切碳纤维增强碳化硅陶瓷基复合材料的高温冲击压缩力学性能

采用先驱体浸渍裂解法(即PIP法)制备出3种不同短切碳纤维(C_(sf))体积分数的圆柱形短切碳纤维增强陶瓷基复合材料(C_(sf)/SiC复合材料)试件,通过高温加热装置和自组装功能的霍普金森压杆装置对试件进行高温和动态荷载耦合作用下的冲击压缩试验,并通过扫描电子显微镜(SEM)观察C_(sf)/SiC复合材料断口形貌,对试件的破坏形态进行分析。试验结果表明,采用PIP法制备的C_(sf)/SiC复合材料试件中C_(sf)分布均匀,在外应力作用下C_(sf)/SiC复合材料试件发生破坏,碳纤维和碳纤维束与SiC基体脱粘被不断拔出。试件的抗压强度随C_(sf)体积含量的增加而呈现先增加后减小的变化趋势,C_(sf)体积含量为21%的试件抗压强度最高,为96.55 MPa。与常温相比,在高温压缩试验中随着复合材料试件平均温度的升高,C_(sf)/SiC复合材料试件破碎后的块度越来越大,整体性越来越好,当温度达到300℃时,C_(sf)体积含量对C_(sf)/SiC复合材料试件抗压强度的影响较小。     

Photoluminescent two-dimensional SiC quantum dots for cellular imaging and transport

Two-dimensional (2D) ultrathin SiC has received intense attention due to its broad band gap and resistance to large mechanical deformation and external chemical corrosion. However, the synthesis and application of ultrasmall 2D SiC quantum dots (QDs) has not been explored. Herein, we synthesize a type of monolayered 2D SiC QDs with advanced photoluminescence (PL) properties via a facile hydrothermal route. Their average size and thickness can be easily adjusted by altering the reaction time. The ultrasmall 2D SiC QDs exhibit a long fluorescence lifetime of 2.59 μs due to efficient quantum confinement. The applications of SiC QDs are demonstrated through labeling A549, HeLa, and NHDF cells and delivering agents for intracellular low-abundant microRNA (miRNA) detection. This advance in preparing photoluminescent SiC QDs is of great significance for broadening their potential in biomedical and optical applications.

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基于PCIe接口的千兆AFDX TAP卡设计与实现

近年来,大通信量使得机载网络对带宽的需求逐渐增长,目前的10/100 Mbps传输速率已经不能满足需求,故千兆AFDX技术研究急需开展;基于千兆AFDX网络,对TAP卡设计和实现进行了研究;通过系统设计和详细设计对设计过程中的问题进行分析,提出了一种基于FPGA的TAP卡设计方法;模拟不同的网络情况对设计进行了验证;结果表明该设计可以正确反映网络细节,能够给网络级调试带来了极大的便利。     

Shape "break-and-repair" strategy and its application to automated medical image segmentation

In three-dimensional medical imaging, segmentation of specific anatomy structure is often a preprocessing step for computer-aided detection/diagnosis (CAD) purposes, and its performance has a significant impact on diagnosis of diseases as well as objective quantitative assessment of therapeutic efficacy. However, the existence of various diseases, image noise or artifacts, and individual anatomical variety generally impose a challenge for accurate segmentation of specific structures. To address these problems, a shape analysis strategy termed "break-and-repair" is presented in this study to facilitate automated medical image segmentation. Similar to surface approximation using a limited number of control points, the basic idea is to remove problematic regions and then estimate a smooth and complete surface shape by representing the remaining regions with high fidelity as an implicit function. The innovation of this shape analysis strategy is the capability of solving challenging medical image segmentation problems in a unified framework, regardless of the variability of anatomical structures in question. In our implementation, principal curvature analysis is used to identify and remove the problematic regions and radial basis function (RBF) based implicit surface fitting is used to achieve a closed (or complete) surface boundary. The feasibility and performance of this strategy are demonstrated by applying it to automated segmentation of two completely different anatomical structures depicted on CT examinations, namely human lungs and pulmonary nodules. Our quantitative experiments on a large number of clinical CT examinations collected from different sources demonstrate the accuracy, robustness, and generality of the shape "break-and-repair" strategy in medical image segmentation.     

.NET环境下MFC框架应用的包装集成技术研究

为有效解决.NET应用中对MFC遗留应用系统的快速集成问题,并尽量重用已有系统,研究了.NET环境下MFC应用系统的包装集成技术,提出了用混合DLL方式来对MFC应用进行大粒度封装的方案.在此基础上开发了一个包装器中间件,对该中间件的体系结构进行了分析,叙述了中间件主要组成部分的关键实现技术,然后给出了一个实例.实践结果表明,该技术是行之有效的,能够满足许多应用系统的需求,提高开发效率.     

Analysis and application of Bio-Inspired Multi-Net Security Model

With the rapid development of network technologies and deteriorating of network environment, traditional single-net security system cannot satisfy the security requirement. The excellent security performance of biological systems impels the bio-inspired network security theory to be a hot research area currently. Based on Bio-inspired Multidimensional Network Security Model we have put forward, we have advanced Bio-inspired Multi-Net Security system by implementing the functional distribution of different subnets of different transient states in Multi-Net Paralleling structure. Firstly, parameter estimation and modified algorithms of Hidden Markov Model are introduced to construct the mathematical mode of B-MNS; secondly, the integrated performance of our modified B-MNS has been tested and its simulation has been carried out. So the feasibility, validity and high efficiency of our model have been demonstrated theoretically, and practically.     

Linking denotational semantics with operational semantics for web services

Web Services have become more and more important in these years, and BPEL4WS (BPEL) is a de facto standard for the web service composition and orchestration. It contains several distinct features, including the scope-based compensation and fault handling mechanism. The denotational semantics and operational semantics have been explored for BPEL. The two semantic models should be consistent. This paper considers the linking of these two semantics. Our approach is to derive the denotational semantics from operational semantics for BPEL, which aims for the consistency of the two models. Moreover, the derivation can be applied in exploring the program equivalence easily, especially for parallel programs.