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To date, the use of biomarkers has become generally accepted. Biomarker‐driven research has been proposed as a successful method to assess the exposure to xenobiotics by using concentrations of the parent compounds and/or metabolites in biological matrices such as urine or blood. However, the identification and validation of biomarkers of exposure remain a challenge. Recent advances in high‐resolution mass spectrometry along with new analytical (post‐acquisition data‐mining) techniques will improve the quality and output of the biomarker identification process. Chronic or even acute exposure to mycotoxins remains a daily fact, and therefore it is crucial that the mycotoxins’ metabolism is unravelled so more knowledge on biomarkers in humans and animals is acquired. This review aims to provide the scientific community with a comprehensive overview of reported in vitro and in vivo mycotoxin metabolism studies in relation to biomarkers of exposure for deoxynivalenol, nivalenol, fusarenon‐X, T‐2 toxin, diacetoxyscirpenol, ochratoxin A, citrinin, fumonisins, zearalenone, aflatoxins, and sterigmatocystin.  相似文献   
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Scientometrics - This study aims to analyze 343 retraction notices indexed in the Scopus database, published in 2001–2019, related to scientific articles (co-)written by at least one author...  相似文献   
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Chemiresistive polymer composite ribbons that function as chemical detectors were produced from solution-cast films of polymers and carbon composites. An array with multiple polymer sensor threads was exposed to dimethyl methyl phosphonate, a nerve agent simulant, and different interferents in the vapor phase. Principal component analysis was used to differentiate between the analytes. The response of the ribbon sensors as a function of the carbon composite and the host polymer source was investigated. The freestanding threads/sensors were mounted into a cell perpendicular to the gas flow to provide little pressure drop and were imbedded into fabrics to provide an example of a small, low-cost, wearable chemical sensor. © 2012 Wiley Periodicals, Inc. J Appl Polym Sci, 2012  相似文献   
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The sliding window approach is the most widely used technique to detect an object from an image. In the past few years, classifiers have been improved in many ways to increase the scanning speed. Apart from the classifier design (such as the cascade), the scanning speed also depends on a number of different factors (such as the grid spacing, and the scale at which the image is searched). When the scanning grid spacing is larger than the tolerance of the trained classifier it suffers from low detections. In this paper, we present a technique to reduce the number of missed detections when fewer subwindows are processed in the sliding window approach for face detection. This is achieved by using a small patch to predict the location of the face within a local search area. We use simple binary features and a decision tree for location estimation as it proved to be efficient for our application. We also show that by using a simple interest point detector based on quantized gradient orientation, as the front-end to the proposed location estimation technique, we can further improve the performance. Experimental evaluation on several face databases show better detection rate and speed with our proposed approach when fewer number of subwindows are processed compared to the standard scanning technique.  相似文献   
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The mechanics of granular media at low liquid saturation levels remain poorly understood. Macroscopic mechanical properties are affected by microscale forces and processes, such as capillary forces, inter-particle friction, liquid flows, and particle movements. An improved understanding of these microscale mechanisms is important for a range of industrial applications and natural phenomena (e.g. landslides). This study focuses on the transient evolution of the tensile stress of unsaturated granular media under extension. Experimental results suggest that the stress state of the material evolves even after cessation of sample extension. Moreover, we observe that the packing density strongly affects the efficiency of different processes that result in tensile stress relaxation. By comparing the observed relaxation time scales with published data, we conclude that tensile stress relaxation is governed by particle rearrangement and fluid redistribution. An increased packing density inhibits particle rearrangement and only leaves fluid redistribution as the major process that governs tensile stress relaxation.  相似文献   
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