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51.
Andrea Bettidi Antonio Cetronio Walter Ciccognani Marco De Dominicis Claudio Lanzieri Ernesto Limiti Antonio Manna Marco Peroni Claudio Proietti Paolo Romanini 《国际射频与微波计算机辅助工程杂志》2009,19(5):598-606
In this article, the design, fabrication, and on‐wafer test of X‐Band and 2–18 GHz wideband high‐power SPDT MMIC switches in AlGaN/GaN technology are presented. The switches have demonstrated state‐of‐the‐art performance and RF fabrication yield better than 65%. Linear and power measurements for different control voltages have been reported and an explanation of the dependence of the power performances on the control voltage is given. In particular, the X‐band switch exhibits a 0.4 dB compression level at 10 GHz when driven by a 38 dBm input signal. The wideband switch shows a compression level of 1 dB at an input drive higher than 38 dBm across the entire bandwidth. © 2009 Wiley Periodicals, Inc. Int J RF and Microwave CAE, 2009. 相似文献
52.
Marco A. Loza-Mejía Rafael Castillo Alfonso Lira-Rocha 《Journal of molecular graphics & modelling》2009,27(8):55
Although 9-anilinoacridines are among the best studied antitumoral intercalators, there are few studies about the effect of isosteric substitution of a benzene moiety for a heterocycle ring in the acridine framework. According to these studies, this approach may lead to effective cytotoxic agents, but good cytotoxic activity depends on structural requirements in the aniline ring which differ from those in 9-anilinoacridines. The present paper deals with molecular modeling studies of some 9-anilino substituted tricyclic compounds and their intercalation complexes (in various DNA sequences) resulting from docking the compounds into various DNA sequences. As expected, the isosteric substitution in 9-anilinoacridines influences the LUMO energy values and orbital distribution, the dipole moment, electrostatic charges and the conformation of the anilino ring. Other important differences are observed during the docking studies, for example, changes in the spatial arrangement of the tricyclic nucleus and the anilino ring at the intercalation site. Semiempirical calculations of the intercalation complexes show that the isosteric replacement of a benzene ring in the acridine nucleus affects not only DNA affinity but also base pair selectivity. These findings explain, at least partially, the different structural requirements observed in several 9-anilino substituted tricyclic compounds for cytotoxic activity. Thus, the data presented here may guide the rational design of new agents with different DNA binding properties and/or a cytotoxic profile by isosteric substitution of known intercalators. 相似文献
53.
54.
Efficient application identification and the temporal and spatial stability of classification schema
Motivated by the importance of accurate identification for a range of applications, this paper compares and contrasts the effective and efficient classification of network-based applications using behavioral observations of network-traffic and those using deep-packet inspection.Importantly, throughout our work we are able to make comparison with data possessing an accurate, independently determined ground-truth that describes the actual applications causing the network-traffic observed.In a unique study in both the spatial-domain: comparing across different network-locations and in the temporal-domain: comparing across a number of years of data, we illustrate the decay in classification accuracy across a range of application–classification mechanisms. Further, we document the accuracy of spatial classification without training data possessing spatial diversity.Finally, we illustrate the classification of UDP traffic. We use the same classification approach for both stateful flows (TCP) and stateless flows based upon UDP. Importantly, we demonstrate high levels of accuracy: greater than 92% for the worst circumstance regardless of the application. 相似文献
55.
Claudio Agostino Ardagna Marco Cremonini Gabriele Gianini 《Journal of Systems Architecture》2009,55(4):243-254
Mobile network providers have developed a variety of location-based services (LBSs), such as friend-finder, point of interest services, emergency rescue and many other safety and security services. The protection of location-privacy has consequently become a key aspect to the success of LBSs, since users consider their own physical location and movements highly privacy-sensitive, and demand for solutions able to protect such an information in a variety of environments. The idea behind location-privacy protection is that the individual should be able to set the level at which the location information is released to avoid undesired exploitation by a potential attacker: one of the approaches to this problem is given by the application of spatial obfuscation techniques, actuated by a trusted agent, and consisting in artificial perturbations of the location information collected by sensing technologies, before its disclosure to third parties. In many situations, however, landscape/map information can help a third party to perform Bayesian inference over spatially obfuscated data and to refine the user’s location estimate up to a violation of the original user’s location-privacy requirements. The goal of this paper is to provide a map-dependent obfuscation procedure that enables the release of the maximum possible user’s location information, that does not lead to a violation of the original user’s location-privacy requirements, even when refined through map-based inference. 相似文献
56.
Product features and task effects on experienced richness, control and engagement in voicemail browsing 总被引:1,自引:0,他引:1
Marco Rozendaal David V. Keyson Huib de Ridder 《Personal and Ubiquitous Computing》2009,13(5):343-354
A recent focus is on creating engaging user experiences with digital products and services such as voicemail. This study aims
to design towards increased levels of engagement in voicemail browsing by using the ‘Richness, Control and Engagement’ (RC
& E) framework. This framework explains the levels of engagement in terms of the levels of richness and control that are shaped
by the features of a product and the user’s expertise. A product was developed that utilized gestures and sound to access
digital voicemail contents. An experiment was conducted in which 28 participants interacted with the product while varying
(1) the number of features of the user interface, (2) the amount of voicemail content and (3) the type of task. Results showed
that the levels of engagement could be predicted according to the levels of richness and control experienced when a task-term
was added to the framework. Implications of the refined RC & E framework for interaction design practice are discussed. 相似文献
57.
Marco Bakera Tiziana Margaria Clemens D. Renner Bernhard Steffen 《Innovations in Systems and Software Engineering》2009,5(3):211-228
We show on a case study from an autonomous aerospace context how to apply a game-based model-checking approach as a powerful
technique for the verification, diagnosis, and adaptation of system behaviors based on temporal properties. This work is part
of our contribution within the SHADOWS project, where we provide a number of enabling technologies for model-driven self-healing.
We propose here to use GEAR, a game-based model checker, as a user-friendly tool that can offer automatic proofs of critical
properties of such systems. Although it is a model checker for the full modal μ-calculus, it also supports derived, more user-oriented logics. With GEAR, designers and engineers can interactively investigate
automatically generated winning strategies for the games, by this way exploring the connection between the property, the system,
and the proof.
This work has been partially supported by the European Union Specific Targeted Research Project SHADOWS (IST-2006-35157), exploring a Self-Healing Approach to Designing cOmplex softWare Systems. The project’s web page is at .
This article is an extended version of Renner et al. [18] presented at ISoLA 2007, Poitiers, December 2007. 相似文献
58.
Anti-reflective (AR) boundary conditions (BC) have been introduced recently in connection with fast deblurring algorithms,
both in the case of signals and images. Here we extend such BCs to d dimensions (d ≥ 1) and we study in detail the algebra induced by the AR-BCs, with strongly symmetric point spread functions (PSF), both
from a structural and computational point of view. The use of the re-blurring idea and the computational features of the AR-algebra
allow us to apply Tikhonov-like techniques within O(n
d
log(n)) arithmetic operations, where n
d
is the number of pixels of the reconstructed object. Extensive numerical experimentation concerning 2D images and strongly
symmetric PSFs confirms the effectiveness of our proposal.
相似文献
59.
Marco Paluszny 《Computer aided design》2008,40(1):56-61
We consider patches that contain any given 3D polynomial curve as a pregeodesic (i.e. geodesic up to reparametrization). A curve is a pregeodesic if and only if its rectifying plane coincides with the tangent plane to the surface, we use this fact to construct ruled cubic patches through pregeodesics and bicubic patches through pairs of pregeodesics. We also discuss the G1 connection of (1,k) patches with abutting pregeodesics. 相似文献
60.
J García Marco A Miguel Sosa J García Conde A Miguel García C Arbona V Escrig I Benet I Navarro A Ruiz F Carbonell 《Canadian Metallurgical Quarterly》1994,39(4):241-244
PURPOSE: To assess the "in vivo" effect of 13-cis-retinoic acid and low dose Ara-C in MDS as well as to establish "in vitro" advantage of retinoid dose-related growth pattern on bone marrow cultures as defined by culture timing and CFU-GM proliferative response. PATIENTS AND METHODS: We evaluated 28 patients diagnosed of MDS according to FAB classification, of whom 4 cases had RA, 8 cases SRA, 14 cases RAEB and 2 cases RAEB-T. Patients who had RA and SRA were treated with oral 13-cis-retinoic acid at doses of 20-40 mg daily for 4 months and those cases with RAEB and RAEB-T had subcutaneous Ara-C at doses of 3 mg/m2 twice a day for 21 days. The "in vivo" and "in vitro" effect of retinoic acid on the haemopoietic differentiation was evaluated by the growth CFU-GM in semisolid cell culture methods. RESULTS: Increasing in vitro concentrations of 13-cis retinoic acid did not enhance the growth of myelodysplastic progenitors. Nevertheless, our study did not find any beneficial therapeutic effect of retinoic compounds in MDS patients. In this study, low-dose Ara-C (3 mg/m2) showed similar effects when compared with higher doses reported by others. Furthermore, in terms of CFU-GM proliferation the concentration of colonies before and after treatment were fairly similar in all but two patients. CONCLUSIONS: The results drawn from our study demonstrated that there is no beneficial advantage of 13-cis-retinoic acid as a differentiation inducing agent on myelodysplastic patients. In contrast, lower doses of Ara-C showed similar effects on haemopoiesis of MDS patients than standard doses of 10-20 mg/m2 but with less side effects. 相似文献