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61.
Hagen Seifert Nicola Ranieri Quinn Smithwick Markus Gross 《Journal of the Society for Information Display》2016,24(9):552-562
We propose two methods to increase the pixel and spatial resolution of Digital Micromirror Devices (DMD)‐based projectors by utilizing the large bandwidth provided by their high pattern rates. By varying the intensity of the illumination for each binary pattern displayed on the DMD, the time required to display an 8‐bit grayscale image can be reduced by up to factor 32 compared to using constant illumination and binary pulse‐width modulation (BPWM). The high image rate projection is then spatially separated by either using a galvanometer scanner or sequentially illuminating the DMD from different directions, thus creating multiple independently addressable projections which are then tiled to form a larger, higher resolution image. 相似文献
62.
63.
Markus Kostrzewa Katrin Sparbier Thomas Maier Sören Schubert 《Proteomics. Clinical applications》2013,7(11-12):767-778
MALDI-TOF MS profiling for microorganism detection has already been demonstrated in the 1990s, but has evolved to the first-line identification method in many laboratories just during the past five years. While this application of MALDI-TOF MS has proven its broad applicability, accuracy, robustness, and cost-effectiveness it is of particular interest to expand the capabilities of the mass spectrometric platform. Resistance detection is the most desirable further application of MALDI-TOF MS in microbiology, but maybe also the most challenging. Different approaches have been published regarding diverse antibiotic drugs and distinct microorganism classes. The current review shall give an overview about the developments of the recent years and their potential to get transformed in clinical useful assays in the future. 相似文献
64.
Olaf Mersmann Bernd Bischl Heike Trautmann Markus Wagner Jakob Bossek Frank Neumann 《Annals of Mathematics and Artificial Intelligence》2013,69(2):151-182
Meta-heuristics are frequently used to tackle NP-hard combinatorial optimization problems. With this paper we contribute to the understanding of the success of 2-opt based local search algorithms for solving the traveling salesperson problem (TSP). Although 2-opt is widely used in practice, it is hard to understand its success from a theoretical perspective. We take a statistical approach and examine the features of TSP instances that make the problem either hard or easy to solve. As a measure of problem difficulty for 2-opt we use the approximation ratio that it achieves on a given instance. Our investigations point out important features that make TSP instances hard or easy to be approximated by 2-opt. 相似文献
65.
Information-centric networking (ICN) raises data objects to first class routable entities in the network and changes the Internet paradigm from host-centric connectivity to data-oriented delivery. However, current approaches to content routing heavily rely on data-driven protocol events and thereby introduce a strong coupling of the control to the data plane in the underlying routing infrastructure. In this paper, threats to the stability and security of the content distribution system are analyzed in theory, simulations, and practical experiments. We derive relations between state resources and the performance of routers, and demonstrate how this coupling can be misused in practice. We further show how state-based forwarding tends to degrade by decorrelating resources. We identify intrinsic attack vectors present in current content-centric routing, as well as possibilities and limitations to mitigate them. Our overall findings suggest that major architectural refinements are required prior to global ICN deployment in the real world. 相似文献
66.
Juha K. Laurila Daniel Gatica-Perez Imad Aad Jan Blom Olivier Bornet Trinh Minh Tri Do Olivier Dousse Julien Eberle Markus Miettinen 《Pervasive and Mobile Computing》2013,9(6):752-771
This paper presents an overview of the Mobile Data Challenge (MDC), a large-scale research initiative aimed at generating innovations around smartphone-based research, as well as community-based evaluation of mobile data analysis methodologies. First, we review the Lausanne Data Collection Campaign (LDCC), an initiative to collect unique longitudinal smartphone dataset for the MDC. Then, we introduce the Open and Dedicated Tracks of the MDC, describe the specific datasets used in each of them, discuss the key design and implementation aspects introduced in order to generate privacy-preserving and scientifically relevant mobile data resources for wider use by the research community, and summarize the main research trends found among the 100+ challenge submissions. We finalize by discussing the main lessons learned from the participation of several hundred researchers worldwide in the MDC Tracks. 相似文献
67.
Gorka Epelde Eduardo Carrasco Gottfried Zimmermann Jan Alexandersson Robert Neßelrath Markus Dubielzig 《Universal Access in the Information Society》2013,12(1):73-87
This paper presents a new approach to make current and future television universally accessible. The proposed approach provides a means of universal accessibility both for remotely operating the TV set and for interacting with online services delivered through the TV. This proposal is based on the ISO/IEC 24752 “Universal Remote Console” (URC) standard. This standard defines an abstract user interface layer called the “user interface socket” and allows the development of pluggable (plug-in) user interfaces for any type of user and any control device. The proposed approach lays the foundation for the development of advanced user interfaces that can be interacted within various modalities. Different prototypes have been developed based on this approach and tested with end users. The user tests have shown this approach to be a viable option for the proposed scenarios. Based on the experience gathered with the prototypes, recommendations and implementation options are suggested for commercial adoption. 相似文献
68.
针对现代无线通信系统在干扰控制方面越来越高的要求,利用通信帧中子载波的重新分配,提出了帧结构设计中一种新的分数频率复用方法—时频分分数频率复用,并将其与传统的分数频率复用方式进行比较。这一新方法是在对系统容量进行建模之后,综合资源块分配中的时分和频分模式提出的,其对应的帧结构相对于传统的FFR具有更高的调节粒度。实验结果验证了这种设计以少量系统容量为代价,在提升系统公平性、提高边缘用户吞吐率方面的性能优势。 相似文献
69.
van Oostrum J Calonder C Rechsteiner D Ehrat M Mestan J Fabbro D Voshol H 《Proteomics. Clinical applications》2009,3(4):412-422
Controlling aberrant protein kinase activity is a promising strategy for a variety of diseases, particularly cancer. Hence, the development of kinase inhibitors is currently a focal point for pharmaceutical research. In this study we utilize a chip-based reverse phase protein array (RPA) platform for profiling of kinase inhibitors in cell-based assays. In combination with the planar wave-guide technology the assay system has an absolute LOD down to the low zeptomole range. A431 cell lysates were analyzed for the activation state of key effectors in the epidermal growth factor (EGF) and insulin signaling pathways to validate this model for compound screening. A microtiter-plate format for growing, treating, and lysing cells was shown to be suitable for this approach, establishing the value of the technology as a screening tool for characterization of large numbers of kinase inhibitors against a wide variety of cellular signaling pathways. Moreover, the reverse array format allows rapid development of site-specific phosphorylation assays, since in contrast to ELISA type systems only a single antigen-specific antibody is required. 相似文献
70.
Ludovit Markus 《Journal of Intelligent and Robotic Systems》1994,11(1-2):109-116
A general method for solving the robot inverse kinematics problem is presented. The method is based upon the general elimination method to obtain the equivalent system of equations which are triangularized and the solutions of the inverse kinematics problem can be solved by backsubstitutions. 相似文献