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Abstract Volatile organic compounds (VOCs) were measured in the air of 51 renovated rooms in Schleswig-Holstein. The buildings examined were of different types – private flats, schools, kindergartens, office buildings – the only common characteristic being that they had all been renovated within the last two years. Among the dominating substances in the 46/51 complaint cases were well-known substances such as alkylbenzenes or monoterpenes at high concentrations but also less common substances, i.e. those which have only recently been reported as indoor air contaminants, for example phenoxyethanol, 2-(2-butoxyethoxy)-ethylacetate (butyldiglycolacetate) or longifolene (Mohr, 1994) at remarkable concentrations. A tentative investigation was made to identify the simultaneous occurrences of the different substances, especially the uncommon ones with their potential sources, as well as health impairments. Finally, VOC emissions from two carpet glues, suspected during the investigations of playing a role as a potential source of the less common substances, were carefully measured under test chamber conditions. This additional laboratory experiment was made to verify the tendency shown in the field study that modern ecological building materials contain less volatile and less common substances but with increased indoor persistence, that could partially account for the increasing number of complaints in relation to the SBS phenomenon.  相似文献   
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Thrombospondin (TSP) is a multifunctional extracellular matrix protein that plays a role in neuronal migration and axonal outgrowth in the developing central nervous system. In the current study we have examined the localization and regulation of TSP immunoreactivity (TSP-IR) during neuronal regeneration in the axotomized facial motor nucleus using Western blotting and light and electron microscopy. Transection of the facial nerve led to a gradual increase in TSP-IR in the regenerating motoneurons, peaking 4-7 days after injury (DAI). In addition to regenerating neurons, axotomy also caused a rapid upregulation of TSP-IR on activated microglia throughout the facial nucleus, with a maximum of 2-3 DAI, and a second increase at 14-21 DAI on microglial aggregates surrounding degenerating motoneurons and in neuronophagic microglia. In summary, injury leads to the induction of thrombospondin on axotomized neurons and activated microglia, peaking at the times of maximal posttraumatic microglial proliferation and during neuronal phagocytosis. Since thrombospondin is a multimodal extracellular matrix protein with a variety of cell attachment sites, thrombospondin might serve to link microglia and injured neurons, followed by microglial proliferation and removal of the neuronal debris.  相似文献   
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The interplay of structural and magnetic properties of magnetic shape memory alloys is closely related to their composition. In this study the influence of the valence electron concentration on the tetragonal transformation in Ni2Mn1 + xZ1 ? x (Z = Ga, In, Sn, Sb) and Co2Ni1 + xGa1 ? x is investigated by means of ab initio calculations. While the type of magnetic interaction is different for the two series, the trends of the total energy changes under a tetragonal transformation are very similar. We find that tetragonal structures become energetically preferred with respect to the cubic one as the valence electron concentration e/a is increased regardless of the system under consideration. In particular, the energy difference between the austenite and martensite structures increases linearly with e/a, which is in part responsible for the linear increase of the matensite transformation temperature. The substitution of nickel by platinum increases even further the transformation temperature.  相似文献   
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A combination of the phase‐field method for the simulation of the microstructure evolution during solidification with subsequent finite element simulation of fracture appearance in the final solidification structure is proposed for the prediction of the mechanical behavior of Al? Si based casting alloys, including the effect of solidification porosity caused by hydrogen. Metallographic investigations and computer tomographic observations of the as cast microstructure of an Al7%Si0.3%Mg alloy together with the data obtained from mechanical tensile testing are used to compare and validate the simulation results to demonstrate the capabilities as well as current limitations in micromechanical modeling of void containing materials. In micromechanical simulations with the element elimination technique (EET) it is shown that porosity influences the crack path as well as crack propagation by connecting the pores. In the eutectic microstructure without porosity, failure starts to develop in silicon lamellae and proceeds in the ductile matrix. However, in the presence of pores fracture also initiates in silicon, and in the later stages of loading, porosity affects the path of the crack and results in additional crack nucleation, and thus, these pores also influence crack propagation in the matrix.  相似文献   
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