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11.
B. Gobbo D. Balsamo M. Mauri P. Bajardi A. Panisson P. Ciuccarelli 《Computer Graphics Forum》2019,38(3):609-621
In this paper we present Top Tom, a digital platform whose goal is to provide analytical and visual solutions for the exploration of a dynamic corpus of user‐generated messages and media articles, with the aim of i) distilling the information from thousands of documents in a low‐dimensional space of explainable topics, ii) cluster them in a hierarchical fashion while allowing to drill down to details and stories as constituents of the topics, iii) spotting trends and anomalies. Top Tom implements a batch processing pipeline able to run both in near‐real time with time stamped data from streaming sources and on historical data with a temporal dimension in a cold start mode. The resulting output unfolds along three main axes: time, volume and semantic similarity (i.e. topic hierarchical aggregation). To allow the browsing of data in a multiscale fashion and the identification of anomalous behaviors, three visual metaphors were adopted from biological and medical fields to design visualizations, i.e. the flowing of particles in a coherent stream, tomographic cross sectioning and contrast‐like analysis of biological tissues. The platform interface is composed by three main visualizations with coherent and smooth navigation interactions: calendar view, flow view, and temporal cut view. The integration of these three visual models with the multiscale analytic pipeline proposes a novel system for the identification and exploration of topics from unstructured texts. We evaluated the system using a collection of documents about the emerging opioid epidemics in the United States. 相似文献
12.
The incidence of right aneurysms of the innominate or subclavian arteries is not very high. The majority of these aneurysms is placed in the distal segment of subclavian arteries. These aneurysms are involved in the complex of the thoracic outlet compressive neurovascular syndrome, especially in occurrence of the cervical rib. All aneurysms in this region can rupture and embolize. This is the main purpose of surgical management of this clinical entity. The aim of this study is to refer an interesting case history of a relatively young patient with a right aneurysm of the middle portion of left subclavian artery. The patient had no known vascular risks and the aneurysm was asymptomatic, the only sign was the visible and palpable pulsating mass over the left clavicle. The aneurysms of the middle and central portion of the left subclavian artery are usually explored through the left high posterolateral thoracotomy. The authors refer their experience with the use of a modified technique of exposure--supraclavicular (or transclavicular) incision with the subperiostal resection of the medial portion of the clavicle. This approach affords excellent exposure and a safe surgical procedure. This approach has been described in 1988 by H. Machleder. The advantage of this approach is a diminished risk of surgery in comparison with the transthoracic approach. The authors suppose, however, that it can be useful in traumatic or occlusive lesions, as well. 相似文献
13.
Alessia Mauri Alessandra Duse Giacomo Palm Roberto Previtali Stefania Maria Bova Sara Olivotto Sara Benedetti Francesca Coscia Pierangelo Veggiotti Cristina Cereda 《International journal of molecular sciences》2022,23(21)
GLUT1 deficiency syndrome (GLUT1DS1; OMIM #606777) is a rare genetic metabolic disease, characterized by infantile-onset epileptic encephalopathy, global developmental delay, progressive microcephaly, and movement disorders (e.g., spasticity and dystonia). It is caused by heterozygous mutations in the SLC2A1 gene, which encodes the GLUT1 protein, a glucose transporter across the blood-brain barrier (BBB). Most commonly, these variants arise de novo resulting in sporadic cases, although several familial cases with AD inheritance pattern have been described. Twenty-seven Italian pediatric patients, clinically suspect of GLUT1DS from both sporadic and familial cases, have been enrolled. We detected by trios sequencing analysis 25 different variants causing GLUT1DS. Of these, 40% of the identified variants (10 out of 25) had never been reported before, including missense, frameshift, and splice site variants. Their structural mapping on the X-ray structure of GLUT1 strongly suggested the potential pathogenic effects of these novel disease-related mutations, broadening the genotypic spectrum heterogeneity found in the SLC2A1 gene. Moreover, 24% is located in a vulnerable region of the GLUT1 protein that involves transmembrane 4 and 5 helices encoded by exon 4, confirming a mutational hotspot in the SLC2A1 gene. Lastly, we investigated possible correlations between mutation type and clinical and biochemical data observed in our GLUT1DS cohort, revealing that splice site and frameshift variants are related to a more severe phenotype and low CSF parameters. 相似文献
14.
Tiina Komulainen Mauri Sourander Sirkka-Liisa Jms-Jounela 《Computers & Chemical Engineering》2004,28(12):2611-2619
15.
Verônica M. F. Frade Attilio Converti Saleh Al Arni Milena F. Silva Mauri S. A. Palma 《化学工程与技术》2017,40(4):663-669
Enrofloxacin is a synthetic second‐generation fluoroquinolone used as an antimicrobial agent exclusively in veterinary medicine. To simulate the treatment of wastewater contaminated by enrofloxacin, four‐day long fed‐batch runs were carried out according to the Fenton process with an enrofloxacin solution as model, to which hydrogen peroxide and ferrous ion were added twice a day. The residual enrofloxacin concentration was practically coincident to that detected at the end of the batch tests. Hydrogen peroxide was almost completely consumed after each feeding period, while the total organic carbon (TOC) concentration decreased gradually within three days, corresponding to a reduction > 58 %. From the third day on, the TOC falling rate was quite low. A yellow sludge settled due to the precipitation of both Fe(OH)3 and a complex formed by ferric ion with adsorbed enrofloxacin and/or its oxidation products. 相似文献
16.
17.
Mauri Aparecido de Oliveira 《Neural computing & applications》2011,20(5):687-701
The objective of this article is to find out the influence of the parameters of the ARIMA-GARCH models in the prediction of
artificial neural networks (ANN) of the feed forward type, trained with the Levenberg–Marquardt algorithm, through Monte Carlo
simulations. The paper presents a study of the relationship between ANN performance and ARIMA-GARCH model parameters, i.e.
the fact that depending on the stationarity and other parameters of the time series, the ANN structure should be selected
differently. Neural networks have been widely used to predict time series and their capacity for dealing with non-linearities
is a normally outstanding advantage. However, the values of the parameters of the models of generalized autoregressive conditional
heteroscedasticity have an influence on ANN prediction performance. The combination of the values of the GARCH parameters
with the ARIMA autoregressive terms also implies in ANN performance variation. Combining the parameters of the ARIMA-GARCH
models and changing the ANN’s topologies, we used the Theil inequality coefficient to measure the prediction of the feed forward
ANN. 相似文献
18.
P systems and Brane calculi are two (families of) computational models inspired by the structure and the functioning of living cells. Although they have different goals there is a recent growing of interests in results that bridge the two research areas.Here we consider an important kind of communication based on the natural budding of mobile membranes (e.g., Golgi apparatus) that is already defined for P systems and we show how to construct an analogous communication in the basic Phago/Exo/Pino Brane calculus. 相似文献
19.
Alginate and alginate/hyaluronic acid membranes generated by electrospinning in wet conditions: Relationship between solution viscosity and spinnability 下载免费PDF全文
The methodology to create alginate and alginate/hyaluronic acid membranes, which involves wet conditions electrospinning, is presented in this paper. The wet conditions allow simultaneously to work in water solutions avoiding the toxic solvents and to obtain crosslinked alginate. An accurate rheological characterization of all solutions examined is performed. By optimizing the electrospinning parameters, it is possible to obtain alginate membranes with homogeneous nanofibers and a narrow diameter distribution (i.e., around 100 nm) as well as alginate/hyaluronic acid membranes characterized by a network of bimodal distribution of the dimensions, namely nanofibers with a diameter comparable to the ones of the alginate membrane, in which are blocked microfibers with a ribbon like appearance, as observed in the SEM images. In order to facilitate the electrospinning process, poly(ethylene oxide) is added to the solutions and then removed after membranes preparation, as demonstrated by the differential scanning calorimetry results, obtaining membranes made up only biopolymers. © 2018 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2018 , 135, 46390. 相似文献
20.
Mapelli F. L. Tarsitano D. Mauri M. 《Industrial Electronics, IEEE Transactions on》2010,57(2):598-607