Protein binding study of isoflavone, perillyl alcohol and S-ibuprofen by high-performance frontal analysis

High-performance frontal analysis (HPFA) was used for a protein binding study of isoflavones (daidzein, genistin, and genistein), enantiomers of perillyl alcohol and S-ibuprofen to human serum albumin (HSA). The analyses were performed on a Develosil and Inertsil 100-Diol-5 column (10 cm×4.6mm). Sodium phosphate solution (pH 7.4, ionic strength 0.17) was used as the mobile phase at a flow rate of 1 ml/min. To ensure the drug to be eluted as a trapezoidal peak with a plateau, injection volumes were each fixed up the zonal profile with an evident plateau appears. The unbound drug concentration was determined from a plateau height of the plateau region after that experimental data were fitted by Scatchard equation. The binding constants (K) and total binding affinities (nK) of drugs to HSA were calculated, respectively.     

制度管理与自我平衡——浅谈高职学生的心理素质教育

心理健康不仅是时代发展对教育的必然要求,而且是实施素质教育的目标之一。为了培养高职学生良好的心理素质,针对高职学生心理素质存在的问题,就如何加强学生心理素质教育进行了探讨。     

Structural study of cubic pyrochlores based on quantum mechanical simulation

In the ideal A₂B₂O₆O′ pyrochlore structure, the x-value of O atom position is a variable parameter. In Bi_1.5ZnNb_1.5−xTa_xO₇ (BZNT) cubic pyrochlores, the x-values alter with the different compositions of Nb/Ta. In this work, a series of initial models for BZNT were established by analyzing X-ray diffraction data. Then three structure modifying methods, including Rietveld refinement, Rietveld refinement with energy and geometry optimization based on quantum mechanics, were employed to obtain the precise models using Materials Studio. Moreover, the reflectivities of BZNT were computed by quantum mechanical simulation based on the refined models. Comparing the simulation results from different modifying models with the experimental results, it is found that Rietveld refinement with energy optimization is the most accurate method for BZNT pyrochlores. According to the simulation results, the different reflectivities correspond well with various x-values of O atom positions in BZNT pyrochlores.     

建筑工程中渗漏质量通病的原因及防治措施

对浴厕这一容易引发渗漏质量通病的环节作了原因分析，从严格精确预留管道洞口，严把材料关等方面，提出了相应的预防措施，并指出治理渗漏应采取全面分析综合治理的原则。     

Ionothermal synthesis of a three-dimensional zinc phosphate with DFT topology using unstable deep-eutectic solvent as template-delivery agent

A three-dimensional zinc phosphate compound with DFT topology, designated as ZnPO₄-EU1, has been synthesized by an ionothermal approach from the system HF-ZnO–P₂O₅-choline chloride-imidazolidone. Ethylenediamine, derived from decomposition of the imidazolidone component of the deep-eutectic solvent (DES) itself, is delivered to the synthesis and serves as an appropriate template for ZnPO₄-EU1. Experiments in which the synthesis conditions were varied showed that ZnPO₄-EU1 may be prepared over a wide molar ratio of P/Zn = 0.55–13.0. Powder X-ray diffraction patterns have been obtained at intervals to track the crystallization process of this material. The experimental data show that Zn₃(PO₄)₂ · 4H₂O (a dense phase) was first isolated from the DES after reaction for 1 h. Subsequently, the pure phase of ZnPO₄-EU1 was obtained with increasing crystallization time from 12 h to 72 h. The experimental results show that the nucleation and crystallization take place with relatively low levels of solvent degradation, demonstrating that zinc phosphate with a three-dimensional framework can be synthesized by in situ generation of an appropriate template using an unstable DES at high temperatures (150–200 °C).     

Polyetherimide substrates for future high density optical data storage

Polyetherimide (PEI) substrate for next‐generation high density optical data storage is fabricated and characterized. Cover‐layer incident or first‐surface recording configurations do not require optical properties of the substrate, which are the prerequisite conditions for the conventional material of polycarbonate (PC). Instead of the optical properties, good mechanical properties with a sufficient transcribability are required. Even though PEI has higher glass transition temperature than that of PC, a microscopic transcribability of PEI is comparable with PC by laminating a thermal insulation layer on the backside of a stamper to retard the heat flow. A macroscopic warpage of PEI substrate is smaller than that of PC substrates, which reduces tilt and servo burden. The lowest critical speed coupled with the flutter of PEI substrate is larger than that of PC substrate because of the mechanical properties of PEI. POLYM. ENG. SCI., 48:97–101, 2008. © 2007 Society of Plastics Engineers     

装配式基坑支护结构在广州地区的应用

装配式基坑支护结构是将基坑支护的围护结构部分在工厂预制成型,再在现场与撑或锚装配组成的支护结构。工程实践表明,此项技术可有效节省工程投资、缩短工期。     

百年夫妻树 专业安全移新居——120年广玉兰搬迁实录

“深情厚意含笑花，尽在嫣然一笑中。”“一点瓜香破醉眠，误他诗客枉流涎。”这是诗人对含笑的赞美。她生长在南方，有淡黄、白、紫等色，花以紫色为大，香以白色为最，形似小白莲，春秋两度开花，花香四溢。宋朝诗人杨万里特别喜爱含笑，于杭州宅内庭院中栽种多株，闲来赏花赋诗多首，其中如《含笑花》七律云：“菖蒲节序芰荷时，翠羽衣裳白玉肌；暗折花房须日暮，遥将香气报人知。半开微吐长怀宝，欲说还休竟俯眉；树脆枝柔惟叶健，不消更画只消诗。”     

一种基于新型寄存器结构的逐次逼近A/D转换器

介绍了一种10位CMOS逐次逼近型A/D转换器。在25 kSPS采样频率以下,根据模拟输入端输入的0~10 V模拟信号,通过逐次逼近逻辑,将其转化为10位无极性数字码。转换器的SAR寄存器结构采用了一种新的结构来实现D触发器。该转换器采用3μm CMOS工艺制作,信噪比为49 dB,积分非线性为±0.5 LSB。