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21.
Ahmet Gokceoglu Yaning Zou Mikko Valkama Paschalis C. Sofotasios 《Mobile Networks and Applications》2014,19(4):473-486
For the development of highly integrated, flexible and low-cost cognitive radio (CR) devices, simple transceiver architectures, like direct-conversion receiver, are expected to be deployed and provide viable radio frequency (RF) spectrum sensing solutions for practical implementation. Yet, this can be very challenging task especially if spectrum sensing and down-conversion are conducted over multiple RF channels simultaneously for improved efficiency in channel scans. Then, the so-called dirty RF problem that degrades link performance of traditional transmission systems starts to be influential from spectrum sensing perspective as well. The unavoidable RF impairments, e.g., oscillator phase noise in direct-conversion receiver, could generate crosstalk between multiple channels that are down-converted simultaneously, and thus considerably limit the spectrum sensing capabilities. Most of the existing spectrum sensing studies in literature assume an ideal RF receiver and have not considered such practical RF hardware problem. In this article, we study the impact of oscillator phase noise on energy detection (ED) based spectrum sensing in multi-channel direct-conversion receiver scenario. With complex Gaussian primary user (PU) signal models, we first derive the detection and false alarm probabilities in closed-form expression. The analytical results, verified through extensive simulations, show that the wideband multi-channel sensing receiver is very sensitive to the neighboring channel crosstalk induced by oscillator phase noise. More specifically, it is shown that the false alarm probability of multi-channel energy detection increases significantly, compared to the ideal RF receiver case. The exact performance degradation depends on the power of neighboring channels as well as statistical characteristics of the phase noise in the deployed receiver. In order to prevent such performance degradation in spectrum identification, an enhanced energy detection technique is proposed. The proposed technique calculates the leakage power from neighboring channels for each channel and improves the sample energy statistics by subtracting this leakage power from the raw values. An analytical expression is derived for the leakage power which is shown to be a function of power spectral levels of neighboring channels and 3-dB bandwidth of phase noise process. Practical schemes for estimating these two quantities are discussed. Extensive computer simulations show that the proposed enhanced detection yields false alarm rates that are very close to those of an ideal RF receiver and hence clearly outperforms classical energy detection. 相似文献
22.
Bioavailability Studies and in vitro Profiling of the Selective Excitatory Amino Acid Transporter Subtype 1 (EAAT1) Inhibitor UCPH‐102
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Dr. Isabell Haym Dr. Tri H. V. Huynh Dr. Stinne W. Hansen Dr. Martin H. F. Pedersen Dr. Josep A. Ruiz Dr. Mette N. Erichsen Dr. Mikko Gynther Walden E. Bjørn‐Yoshimoto Dr. Bjarke Abrahamsen Dr. Jesper F. Bastlund Dr. Christoffer Bundgaard Anette L. Eriksen Prof. Anders A. Jensen Prof. Lennart Bunch 《ChemMedChem》2016,11(4):403-419
Although the selective excitatory amino acid transporter subtype 1 (EAAT1) inhibitor UCPH‐101 has become a standard pharmacological tool compound for in vitro and ex vivo studies in the EAAT research field, its inability to penetrate the blood–brain barrier makes it unsuitable for in vivo studies. In the present study, per os (p.o.) administration (40 mg kg?1) of the closely related analogue UCPH‐102 in rats yielded respective plasma and brain concentrations of 10.5 and 6.67 μm after 1 h. Three analogue series were designed and synthesized to improve the bioavailability profile of UCPH‐102, but none displayed substantially improved properties in this respect. In vitro profiling of UCPH‐102 (10 μm ) at 51 central nervous system targets in radioligand binding assays strongly suggests that the compound is completely selective for EAAT1. Finally, in a rodent locomotor model, p.o. administration of UCPH‐102 (20 mg kg?1) did not induce acute effects or any visible changes in behavior. 相似文献
23.
Stefanie Kasurinen Pasi I. Jalava Oskari Uski Mikko S. Happo Thomas Brunner Jorma Mäki-Paakkanen 《Aerosol science and technology》2016,50(1):41-51
Wood pellets have been used in domestic heating appliances for three decades. However, because the share of renewable energy for heating will likely rise over the next several years, alternative biomass fuels, such as short-rotation coppice or energy crops, will be utilized. We tested particulate emissions from the combustion of standard softwood pellets and three alternative pellets (poplar, Miscanthus sp., and wheat straw) for their ability to induce inflammatory, cytotoxic, and genotoxic responses in a mouse macrophage cell line. Our results showed clear differences in the chemical composition of the emissions, which was reflected in the toxicological effects. Standard softwood and straw pellet combustion resulted in the lowest PM1 mass emissions. Miscanthus sp. and poplar combustion emissions were approximately three times higher. Emissions from the herbaceous biomass pellets contained higher amounts of chloride and organic carbon than the emissions from standard softwood pellet combustion. Additionally, the emissions of the poplar pellet combustion contained the highest concentration of metals. The emissions from the biomass alternatives caused significantly higher genotoxicity than the emissions from the standard softwood pellets. Moreover, straw pellet emissions caused higher inflammation than the other samples. Regarding cytotoxicity, the differences between the samples were smaller. Relative toxicity was generally highest for the poplar and Miscanthus sp. samples, as their emission factors were much higher. Thus, in addition to possible technical problems, alternative pellet materials may cause higher emissions and toxicity. The long-term use of alternative fuels in residential-scale appliances will require technological developments in both burners and filtration.
Copyright © 2016 American Association for Aerosol Research 相似文献
24.
The present study investigates the early stages in the oxidation process of Sanicro 28 (Fe31Cr27Ni) stainless steel when exposed to an alkali salt (KCl, NaCl or K2CO3) for 2 h at 450 and 535 °C. After the exposure, the oxidized samples were analyzed with a combinatory method (CA, XPS and SEM–EDX). It was found that all three salts were corrosive, and the overall oxidation reaction rate was much higher at 535 °C than at 450 °C. There were clear differences in terms of the impact of cations (Na+, K+) and anions (Cl?, CO3 2?) on the initial corrosion process at both temperatures. When focusing on the cations, the presence of potassium ions resulted in a higher rate of chromate formation than in the presence of sodium ions. When studying the effect of anions, the oxidation of iron and chromium occurred at higher rates in the presence of both chloride salts than in the presence of the carbonate salt, and chloride salts seemed to possess higher diffusion rate in the gas phase and along the surface than carbonate salts. Moreover, at the higher temperature of 535 °C, the formed chromate reacted further to chromium oxide, and an ongoing oxidation process of iron and chromium was identified with a significantly higher reaction rate than at 450 °C. 相似文献
25.
26.
Maarit J. Rein Velimatti Ollilainen Mikko Vahermo Jari Yli-Kauhaluoma Marina Heinonen 《European Food Research and Technology》2005,220(3-4):239-244
In most fruit and berry products the attractive red color is unstable and easily susceptible to degradation. The colors of strawberry and raspberry juices can be enhanced and stabilized by the addition of cinnamic acids. The aim of this study was to identify the novel anthocyanin products responsible for the improved juice color. The pyranoanthocyanins formed were detected using high-performance liquid chromatography, and the fractions from this were analyzed using a nano-ESI tandem MS technique. The pyranoanthocyanins identified were formed from reactions of the main anthocyanins of strawberry and raspberry juices with ferulic acid or sinapic acid. The new anthocyanin derivatives were the 4-vinylguaiacol and 4-vinylsyringol adducts of pelargonidin and cyanidin. This is the first time that pelargonidin 3-glucoside-based vinylphenol pyranoanthocyanins and pyranoanthocyanins with more complex sugar residues have been found. This is also the first time pyranoanthocyanins have been detected in strawberry and raspberry juices. 相似文献
27.
Helmi Keskinen Jyrki M. Mäkelä Mikko Aromaa Jorma Keskinen Sami Areva Cilâine V. Teixeira Jarl B. Rosenholm Viljami Pore Mikko Ritala Markku Leskelä Mari Raulio Mirja S. Salkinoja-Salonen Erkki Levänen Tapio Mäntylä 《Catalysis Letters》2006,111(3-4):127-132
Titania and titania-silver nanoparticle deposits were made by Liquid Flame Spray technique, in which the liquid precursor
is injected into a high temperature flame, where it will evaporate and nucleate to nanosize particles. One-step and two-step
methods were used for preparation of titania-silver deposits. The amount of silver added was 1 wt%. The deposits were collected
in the flame zone on steel and glass surfaces and were analyzed by TEM, EDS, XPS and SAXS. The titania deposits consisted
of porous nanosized titania agglomerates of primary particles (~10 nm). With silver addition, small spherical silver metal
particles (~2 nm) were detected on the agglomerates. An increase in the photocatalytic activity was verified by stearic acid
decomposition and biofilm removal using Deinococcus geothermalis as the model organism. 相似文献
28.
Substantial research suggests that the t10,c12–18:2, but not the c9,t11–18:2, isomer of conjugated linoleic acid (CLA) reduces milk fat synthesis in lactating bovine and rodent species. Because
fat is the major energy-yielding component in human milk, we were interested in whether this is true for women as well. Thus,
the effects of c9,t11–18:2 and t10,c12–18:2 on milk fat were examined in breast-feeding women (n = 12) in a double-blind, placebo-controlled, crossover study with latin-square design. The study was divided into six periods:
baseline (3 days), three intervention periods (5 days each), and two washout periods (9 days each). During each intervention
period, women consumed 750 mg/day of a supplement containing predominantly c9,t11–18:2, t10,c12–18:2, or 18:1 (olive oil placebo). Milk was collected by complete breast expression on the final day of each period. Infant
milk consumption was estimated by 24 h weighing on the penultimate day of each intervention and washout period, and maternal
adiposity (% body fat) was determined at baseline using dual energy X-ray absorptiometry. Milk c9,t11–18:2 and t10,c12–18:2 concentrations were greater (P < 0.05) during the corresponding CLA treatment periods as compared to the placebo period, providing strong evidence of subject
compliance. Both CLA isomers were transferred into milk fat at relatively high efficiency; average transfer efficiency was
estimated to be 23.3%. Compared to the placebo treatment, milk fat content was not reduced during either CLA treatment. Data
indicate that body fatness did not modify any putative effect of isomeric CLA consumption on milk fat concentration. The evidence
from this study suggests that the sensitivity of lactating women’s mammary tissue to an anti-lipogenic effect of the t10,c12–18:2 isoform of CLA may be less than previously hypothesized. 相似文献
29.
建筑通常被认为是老年人的艺术范畴,或者,年轻建筑师和女建筑师做的概念和模型。年龄是影响这一判断的标准。对于20岁的年轻人而言.40岁的人就已经是老朽了。或者从另一个角度来看,建筑师Kristian Gullichsen和Juhani Pallasmaa在20世纪70年代被《赫尔辛基消息报》报导的时候被称为青年建筑师,尽管那时他们已经40多岁了。 相似文献
30.
Vincenzo Di Marzo Mikko Griinari Gianfranca Carta Elisabetta Murru Alessia Ligresti Lina Cordeddu Elena Giordano Tiziana Bisogno Maria Collu Barbara Batetta Sabrina Uda Kjetil Berge Sebastiano Banni 《International Dairy Journal》2010,20(4):231-235
Evidence suggests that dietary long chain polyunsaturated fatty acids (LCPUFAs), and particularly those belonging to the n-3 family, may influence the brain fatty acid profile and, thereby, the biosynthesis of endocannabinoids in rodents. However, the doses used are usually quite high and not comparable with human intake. Recently, we have shown that relatively low doses of dietary n-3 LCPUFAs (4 weeks), in the form of either fish or krill oil, balanced for EPA and DHA content, and against a control diet with no EPA and DHA and similar contents of oleic, linoleic and α-linolenic acids, lower the concentrations of the endocannabinoids, anandamide (AEA) and 2-arachidonoylglycerol (2-AG), in the visceral adipose tissue, and of AEA in the liver and heart, of obese Zucker rats. This, in turn, is associated with lower levels of arachidonic acid in membrane phospholipids and with amelioration of some metabolic syndrome parameters. We investigated here whether in Zucker rats, under the same conditions, fish and krill oil are also able to influence LCPUFA and endocannabinoid profiles in brain. Only krill oil was able to increase significantly DHA levels in brain phospholipids, with no changes in arachidonic acid. DHA increase was associated with lower levels of 2-AG in the brain, whereas AEA and its congeners, N-palmitoylethanolamine and N-oleoylethanolamine, were unchanged. We conclude that, despite the strong impact of dietary n-3 fatty acid on endocannabinoid levels previously observed in peripheral tissues, in the brain only 2-AG is affected by dietary krill oil, suggesting that the beneficial effect of the latter on the metabolic syndrome is mostly exerted by modifying peripheral endocannabinoids. Nevertheless, possible effects of dietary krill oil in the brain through modification of 2-AG levels deserve further investigation. 相似文献