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排序方式: 共有153条查询结果,搜索用时 15 毫秒
21.
Mizuki Ono Tsunehiro Ino Masato Koyama Akira Takashima Akira Nishiyama 《Solid-state electronics》2004,48(12):2191-2198
It is shown that propagation delay time in CMIS (complementary metal insulator semiconductor field effect transistor) inverters is strongly affected by dielectric constant nonuniformity in gate dielectrics caused by the phase separation in silicate films. Influences of such nonuniformity on load capacitance are studied by analytical calculations based on a physical model which takes polarization into account. It is newly found that load capacitances are affected by the phase separation in qualitatively different ways, depending on the average metal concentration of their dielectric films. An experimental result is compared with those calculations. Influences of such nonuniformity on current drivability are studied by 3-dimensional device simulations. It is also newly found that such nonuniformity affects load capacitance and current drivability in different ways, resulting in an increase in propagation delay time of CMIS inverters for all metal concentrations studied. An explanation of this phenomenon is given with physical considerations. 相似文献
22.
Rapid Reconstitution of Biosynthetic Machinery for Fungal Metabolites in Aspergillus oryzae: Total Biosynthesis of Aflatrem
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Koichi Tagami Dr. Atsushi Minami Ryuya Fujii Dr. Chengwei Liu Dr. Mizuki Tanaka Prof. Dr. Katsuya Gomi Prof. Dr. Tohru Dairi Prof. Dr. Hideaki Oikawa 《Chembiochem : a European journal of chemical biology》2014,15(14):2076-2080
Reconstitution of the biosynthetic machinery for fungal secondary metabolites in Aspergillus oryzae provides an opportunity both for stepwise determination of the biosynthetic pathways and the total biosynthesis of fungal natural products. However, to maximize the utility of the reconstitution system, a simple and rapid strategy for the introduction of heterologous genes into A. oryzae is required. In this study, we demonstrated an effective method for introducing multiple genes involved in the biosynthesis of fungal metabolites by using the expression vectors pUARA2 and pUSA2, each of which contains two cloning sites. The successful introduction of all the aflatrem biosynthetic genes (seven genes in total) after two rounds of transformation enabled the total biosynthesis of aflatrem. This rapid reconstitution strategy will facilitate the functional analysis of the biosynthetic machinery of fungal metabolites. 相似文献
23.
Masaaki Hirayama Noriyuki Sonoyama Takeshi Abe Machiko Minoura Masumi Ito Daisuke Mori Atsuo Yamada Ryoji Kanno Takahito Terashima Mikio Takano Kazuhisa Tamura Jun’ichiro Mizuki 《Journal of power sources》2007
A new experimental technique was developed for detecting structure changes at electrode/electrolyte interface of lithium cell using X-ray reflectometry and two-dimensional model electrodes with a restricted lattice-plane. The electrodes were constructed with an epitaxial film of LiCoO2 synthesized by pulsed laser deposition method. The orientation of the epitaxial film depends on the substrate plane; the 2D layer of LiCoO2 is parallel to the SrTiO3 (1 1 1) substrate ((0 0 3)LiCoO2//(1 1 1)SrTiO3), while the 2D layer is perpendicular to the SrTiO3 (1 1 0) substrate ((1 1 0)LiCoO2//(1 1 0)SrTiO3). The anisotropic properties were confirmed by electrochemical measurements. Ex situ X-ray reflectivity measurements indicated that the impurity layer existed on the as-grown LiCoO2 was dissolved and a new SEI layer with lower density was formed after soaking into the electrolyte. In situ X-ray reflectivity measurements indicated that the surface roughness of the intercalation (1 1 0) plane increased with applying voltages, while no significant changes in surface morphology were observed for the intercalation non-active (0 0 3) plane during the pristine stage of the charge–discharge process. 相似文献
24.
INTRODUCTI0NUnsteadyphenomenaappearedinacentrifugalcompressorsystematlowflowratearecharacterizedbysurgeandrotatingstall.Thesurgeisknowntocauseoscillationswithlargeamplitudeofthefiowrateandthepressurerisethrough0utacompressorsys-tem.Ontheotherhand,ther0tatingstallcauseslocalflowoscillationsandappearsinsomepartsofacompressor,suchastheinducer,theimpellerandthediffuser-Sincetheydeterioratethecompressorperfor-manceands0metimesleadtothesystembreakd0wn,itisimportanttoknowthephysicalmechanismsofth… 相似文献
25.
The secondary flow within a passage of turbomachinery exhibits a complex flow pattern by the effect of the centrifugal and the Coriolis forces. The passage vortex in this secondary flow generates a major part of the losses. However, the mechanism of the loss generation has not been fully clarified yet. In this point of view, the passage vortex is closely examined by the computational method using the two-dimensional curved square ducts as fundamental models. The inlet boundary layer thickness and the inlet velocity distortion are considered to be the major parameters affecting the generation of passage vortex in the present study. The computed results revealed that the passage vortex gave the predominant effects for the generation of loss not only in the breakdown process but also in the development process. 相似文献
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27.
M. Lakshmi Kantam Ujjwal Pal B. Sreedhar Suresh Bhargava Yasuhiro Iwasawa Mizuki Tada B.M. Choudary 《Advanced Synthesis \u0026amp; Catalysis》2008,350(9):1225-1229
The selective oxidation of various alcohols into their corresponding aldehydes and ketones was achieved by ruthenium species stabilized on the nanocrystalline magnesium oxide (NAP‐MgO) by the incorporation of choline hydroxide, a basic ionic liquid, in excellent yields. The procedure is simple, efficient and environmentally benign. The catalyst can be used for four cycles with almost consistent activity. 相似文献
28.
A certain amount of hexachlorobenzene (HCB), designated a persistent organic pollutant (POP) by the Stockholm Convention, is emitted from an electric arc furnace (EAF) used in the steelmaking process. To understand the formation and decomposition behaviors of HCB during the treatment of waste gases from an EAF, characterization of dust samples from EAFs in different plants was conducted. Dusts 1 and 2 were bag filter dusts collected from a common steel plant and a special steel plant, respectively. The initial concentrations of HCB in dusts 1 and 2 were 62 and < 0.1 ng/g of dust, respectively. Then a series of heating experiments was carried out with these dust samples under various conditions. The formation of HCB from both dusts was not significant under an Ar atmosphere, although the amount of formation from dust 1 slightly increased with an increase in the holding temperature. Under an Ar--20% O2 atmosphere, however, a remarkable amount of HCB formed from dust 1 above 573 K. A certain amount of HCB was also formed from dust 2, even though the initial concentration of HCB was very low. Moreover, the coexistence of metallic compounds such as CuCl2 had a significant accelerating effect on the formation of HCB. 相似文献
29.
Hiromasa Tanno Emi Kanno Suzuna Sato Yu Asao Mizuki Shimono Shiho Kurosaka Yukari Oikawa Shinyo Ishi Miki Shoji Ko Sato Jun Kasamatsu Tomomitsu Miyasaka Hideki Yamamoto Keiko Ishii Yoshimichi Imai Masahiro Tachi Kazuyoshi Kawakami 《International journal of molecular sciences》2021,22(8)
Chronic infections are considered one of the most severe problems in skin wounds, and bacteria are present in over 90% of chronic wounds. Pseudomonas aeruginosa is frequently isolated from chronic wounds and is thought to be a cause of delayed wound healing. Invariant natural killer T (iNKT) cells, unique lymphocytes with a potent regulatory ability in various inflammatory responses, accelerate the wound healing process. In the present study, we investigated the contribution of iNKT cells in the host defense against P. aeruginosa inoculation at the wound sites. We analyzed the re-epithelialization, bacterial load, accumulation of leukocytes, and production of cytokines and antimicrobial peptides. In iNKT cell–deficient (Jα18KO) mice, re-epithelialization was significantly decreased, and the number of live colonies was significantly increased, when compared with those in wild-type (WT) mice on day 7. IL-17A, and IL-22 production was significantly lower in Jα18KO mice than in WT mice on day 5. Furthermore, the administration of α-galactosylceramide (α-GalCer), a specific activator of iNKT cells, led to enhanced host protection, as shown by reduced bacterial load, and to increased production of IL-22, IL-23, and S100A9 compared that of with WT mice. These results suggest that iNKT cells promote P. aeruginosa clearance during skin wound healing. 相似文献
30.