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101.
Optimizing the production, maintenance and extension of lexical resources is one the crucial aspects impacting natural language processing (NLP). A second aspect involves optimizing the process leading to their integration in applications. With this respect, we believe that a consensual specification on monolingual, bilingual and multilingual lexicons can be a useful aid for the various NLP actors. Within ISO, one purpose of Lexical Markup Framework (LMF, ISO-24613) is to define a standard for lexicons that covers multilingual lexical data.
Claudia SoriaEmail:
  相似文献   
102.
This paper describes an algorithm to enforce hyper-arc consistency of polynomial constraints defined over finite domains. First, the paper describes the language of so called polynomial constraints over finite domains, and it introduces a canonical form for such constraints. Then, the canonical form is used to transform the problem of testing the satisfiability of a constraint in a box into the problem of studying the sign of a related polynomial function in the same box, a problem which is effectively solved by using the modified Bernstein form of polynomials. The modified Bernstein form of polynomials is briefly discussed, and the proposed hyper-arc consistency algorithm is finally detailed. The proposed algorithm is a subdivision procedure which, starting from an initial approximation of the domains of variables, removes values from domains to enforce hyper-arc consistency.  相似文献   
103.
We have investigated the adsorption and reaction of methanol with Au/TiO2 catalysts using a pulsed flow reactor, DRIFTS and TPD. The TiO2 (P25) surface adsorbed a full monolayer of methanol, much of it in a dissociative manner, forming methoxy groups associated with the cationic sites, and hydroxyl groups at the anions. The methoxy is relatively stable until 250 °C, at which point decomposition occurs, producing mainly dimethyl ether by a bimolecular surface reaction. As the concentration of methoxy on the surface diminishes, so the mechanism reverts to a de-oxygenation pathway, producing mainly methane and water (at ~330 °C in TPD), but also with some coincident CO and hydrogen. Au catalysts were prepared by the deposition-precipitation method to give Au loadings between 0.5–3 wt %. The effect of low levels of Au on the reactivity is marked. The pathway which gives methane, which is characteristic of titania, remains, but a new feature of the reaction is the evolution of CO2 and H2 at lower temperature (a peak is seen in TPD at 220 °C), and the elimination of the DME-producing state. Clearly this is associated with the presence of Au and appears to be due to the production of a formate species on the surface of the Au component. This formate species is mainly involved in the reaction of methanol with the Au/TiO2 catalysts which results in a combustion pathway being followed, with complete conversion occurring by ~130 °C.  相似文献   
104.
A leading cause of death in western countries is sudden cardiac death, and can be associated with genetic disease. Next-generation sequencing has allowed thorough analysis of genes associated with this entity, including, most recently, titin. We aimed to identify potentially pathogenic genetic variants in titin. A total of 1126 samples were analyzed using a custom sequencing panel including major genes related to sudden cardiac death. Our cohort was divided into three groups: 432 cases from patients with cardiomyopathies, 130 cases from patients with channelopathies, and 564 post-mortem samples from individuals showing anatomical healthy hearts and non-conclusive causes of death after comprehensive autopsy. None of the patients included had definite pathogenic variants in the genes analyzed by our custom cardio-panel. Retrospective analysis comparing the in-house database and available public databases also was performed. We identified 554 rare variants in titin, 282 of which were novel. Seven were previously reported as pathogenic. Of these 554 variants, 493 were missense variants, 233 of which were novel. Of all variants identified, 399 were unique and 155 were identified at least twice. No definite pathogenic variants were identified in any of genes analyzed. We identified rare, mostly novel, titin variants that seem to play a potentially pathogenic role in sudden cardiac death. Additional studies should be performed to clarify the role of these variants in sudden cardiac death.  相似文献   
105.
Recent natural disasters have led crisis management organizations to revise their protocols so as to rely on the contribution of a wider range of actors, including simple citizens as well as expert operators, to support decision making activities. Reliable and timely information sharing among members of distributed teams of disaster responders has become paramount for the success of the overall crisis management process. In this paper we propose a crisis management system based on spreadsheet-mediated collaboration among on-site responders and decision makers. To share data a common spreadsheet artifact has been developed by using a participatory design approach which is accessed through mobile user interfaces. The evaluation results showed that the use of the spreadsheet artifact has resulted in more effective decision making relating to set of earthquake management scenarios in high-risk areas located in Italy.  相似文献   
106.
107.
This study evaluated newly proposed Human–Machine Interface (HMI) design concepts for improving the ergonomics of hydraulic excavators. The design concepts were based on an augmented interaction technique which involved the use of heads-up display (HUD) and coordinated control as HMI elements. Two alternative HMI designs were elaborated in order to separately evaluate the ergonomic impacts of the head-up display and the coordinated control by comparing them to the standard HMI design. The effectiveness of these three HMI designs in terms of the reduction of the operators' mental and physical workload were assessed by conducting experiments utilizing human subjects, ages 23–35 years. The National Aeronautics and Space Administration's Task Load Index (NASA TLX) method was used for collecting subjective workload scores based on a weighted average of ratings of six factors: Mental Demand, Physical Demand, Temporal Demand, Own Performance, Effort, and Frustration Level. The results showed that the type of HMI design affects different aspects of the operator's workload. Indeed, it showed how the proposed augmented interaction is an effective solution for reducing the ergonomic gaps in terms of mental workload, and to a lesser extent the physical workload, subjected by the standard HMI design.  相似文献   
108.
The main objective of this paper is to solve the bi-objective reliability redundancy allocation problem for series-parallel system where reliability of the system and the corresponding designing cost are considered as two different objectives. In their formulation, reliability of each component is considered as a triangular fuzzy number. In order to solve the problem, developed fuzzy model is converted to a crisp model by using expected values of fuzzy numbers and taking into account the preference of decision maker regarding cost and reliability goals. Finally the obtained crisp optimization problem has been solved with particle swarm optimization (PSO) and compared their results with genetic algorithm (GA). Examples are shown to illustrate the method. Finally statistical simulation has been performed for supremacy the approach.  相似文献   
109.
    
Cancer cells may acquire resistance to stress signals and reprogram metabolism to meet the energetic demands to support their high proliferation rate and avoid death. Hence, targeting nutrient dependencies of cancer cells has been suggested as a promising anti-cancer strategy. We explored the possibility of killing breast cancer (BC) cells by modifying nutrient availability. We used in vitro models of BC (MCF7 and MDA-MB-231) that were maintained with a low amount of sulfur amino acids (SAAs) and a high amount of oxidizable polyunsatured fatty acids (PUFAs). Treatment with anti-apoptotic, anti-ferroptotic and antioxidant drugs were used to determine the modality of cell death. We reproduced these conditions in vivo by feeding BC-bearing mice with a diet poor in proteins and SAAs and rich in PUFAs (LSAA/HPUFA). Western blot analysis, qPCR and histological analyses were used to assess the anti-cancer effects and the molecular pathways involved. We found that BC cells underwent oxidative damage to DNA and proteins and both apoptosis and ferroptosis were induced. Along with caspases-mediated PARP1 cleavage, we found a lowering of the GSH-GPX4 system and an increase of lipid peroxides. A LSAA/HPUFA diet reduced tumor mass and its vascularization and immune cell infiltration, and induced apoptosis and ferroptotic hallmarks. Furthermore, mitochondrial mass was found to be increased, and the buffering of mitochondrial reactive oxygen species limited GPX4 reduction and DNA damage. Our results suggest that administration of custom diets, targeting the dependency of cancer cells on certain nutrients, can represent a promising complementary option for anti-cancer therapy.  相似文献   
110.
Pristine and (SiC+Te)-added MgB2 powders, green and spark plasma sintered (SPS) compacts were investigated from the viewpoint of quasi-static and dynamic (Split-Hopkinson Pressure Bar, SHPB) compressive mechanical properties The amount of the additive (SiC+Te) was selected to be the optimum one for maximization of the superconducting functional parameters. Pristine and added MgB2 show very similar compressive parameters (tan δ, fracture strength, Vickers hardness, others) and fragment size in the SHPB test. However, for the bulk SPSed samples the ratio of intergranular to transgranular fracturing changes, the first one being stronger in the added sample. This is reflected in the quasi-static KIC that is higher for the added sample. Despite this result, sintered samples are brittle and have roughly similar fragmentation behavior as for brittle engineering ceramics. In the fragmentation process, the composite nature of our samples should be considered with a special focus on MgB2 blocks (colonies) that show the major contribution to fracturing. The Glenn-Chudnovsky model of fracturing under dynamic load provides the closest values to our experimental fragment size data.  相似文献   
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