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排序方式: 共有8233条查询结果,搜索用时 15 毫秒
31.
Raquel Alves dos Santos Teresinha Rosa Cabral Isabel Rosa Cabral Lusania Maria Greggi Antunes Cristiane Pontes Andrade Plínio Cerqueira dos Santos Cardoso Marcelo de Oliveira Bahia Claudia Pessoa José Luis Martins do Nascimento Rommel Rodríguez Burbano Catarina Satie Takahashi 《Biocell》2008,32(2):195-200
Physalis angulata L (Solanaceae) is a medicinal plant from North of Brazil, whose different extracts and infusions are commonly used in the popular medicine for the treatment of malaria, asthma, hepatitis, dermatitis and rheumatism. However, the genotoxic effects of P. angulata on human cells is not well known. The main purpose of the present study was to evaluate the in vitro genotoxic effects of aqueous extract of P. angulata using the comet assay and the micronucleus assay in human lymphocytes provided from 6 healthy donors. Treatments with P. angulata extracts were performed in vitro in order to access the extent of DNA damage. The comet assay has shown that treatments with P. angulata at 0.5, 1.0, 2.0, 3.0 and 6.0 microg/mL in culture medium were genotoxic. Lymphocytes treated with P. angulata at the concentrations of 3.0 and 6.0 microg/mL in culture medium showed a statistically significant increase in the frequency of micronucleus (p<0.05), however, the cytokinesis blocked proliferation index (CBPI) was not decreased after P. angulata treatment. In conclusion, the present work demonstrated the genotoxic effects of P. angulata extract on human lymphocytes in vitro. 相似文献
32.
Didier Perrin Céline Guillermain Anne Bergeret José-Marie Lopez-Cuesta Gilles Tersac 《Journal of Materials Science》2006,41(12):3593-3602
A new process of management of waste of composite materials from Sheet Moulding Compounds (SMC), as reinforcing fillers for
thermoplastic materials, including both mechanical and chemical processes is proposed in this paper. Communited SMC being
composed of coated glass fibres intimately mixed with calcium carbonate powder, their reinforcing power is low. First, the
fibrous part was increased by partial dissolution of calcium carbonate present in the crushed products SMC. Second, a process
of partial solvolysis was developed aiming at strong increasing the interfacial mechanical properties by functionalising of
SMC load incorporated into polypropylene/grafted maleic anhydride polypropylene (PP/PPgma). At this effect, we investigated a treatment with a hot triamine (diethylenetriamine, DETA) in order to create a functionalisation,
after scission of the bond ester of unsaturated polyester, as bridging amino-succinimide.The effect of this recycling way
by partial solvolysis was checked from the mechanical properties of the resulting reinforced PP/PPgma material: Although a lower of Young modulus, better yield stress and especially resilience were observed. 相似文献
33.
Montserrat Bóo Francisco Argüello Javier D. Bruguera Emilio L. Zapata 《The Journal of VLSI Signal Processing》1997,17(1):57-73
A rate 1/n binary generic convolutional encoder is a shift-register circuit where the inputs are information bits and the outputs are blocks of n bits generated as linear combinations on the appropriate shift register contents. The decoding of the outputs of a convolutional encoder can be carried out by the well-known Viterbi algorithm. The communication pattern of the Viterbi Algorithm is given as a graph, called trellis, associated to the state diagram of the corresponding encoder. In this paper we present a methodology that permits the efficient mapping of the Viterbi algorithm onto a column of an arbitrary number of processors. This is done through the representation of the data flow by using mathematical operators which present an inmediate hardware projection. A single operator string has been obtained to represent a generic encoder through the study of the data flow of free-forward encoders and feed-back encoders. The formal model developed is employed for the partitioning of the computations among an arbitrary number of processors in such a way that the data are recirculated opimizing the use of the processors and the communications. As a result, we obtain a highly regular and modular architecture suitable for VLSI implementation. 相似文献
34.
Gerardo Gabriel Acosta Miguel Angel Mayosky José Maria Catalfo 《Applied Intelligence》1994,4(1):53-66
This article proposes a scheme for the on-line adjustment of three mode controller settings based on experimental measurements of closed-loop performance. It uses a recently developed heuristic tuning procedure to identify estimated process parameters. This method may give rise to conflicting estimates. Fuzzy Set theory is applied to manage the situation in terms of a fuzzy conjunction to combine the various estimates. PID control was chosen because of its wide use in the industrial environment due to driving simplicity and robustness. The article shows design, development, and computer simulation aspects. 相似文献
35.
The purpose of this study was to examine whether anxiety-related cognitive bias for threat is stronger for threatening pictures than for threatening words. Spider-phobic participants (n?=?31 ) and control participants (n?=?33) performed a pictorial and linguistic spider Stroop task. Spider-phobic participants showed a marked bias for threat. However, this bias was similar for pictures and for words, although the spider-phobic group evaluated the pictures as being more aversive. The results suggest that automatic processing of threatening information in people with phobias is triggered in an on-off fashion, independent of subjective threat of the stimuli. This lack of distinction in automatic processing of weak and strong predictors of danger may be fundamental to the irrational nature of anxiety disorders. (PsycINFO Database Record (c) 2010 APA, all rights reserved) 相似文献
36.
37.
Lázaro Valentin Zuquette Janaina Barrios Palma Osni José Pejon 《Bulletin of Engineering Geology and the Environment》2005,64(3):257-271
There are more than 20,000 uncontrolled sanitary landfill areas in Brazil. The paper reports an integrated study undertaken
to develop an environmental assessment of the uncontrolled sanitary landfill area of the city of Po?os de Caldas, State of
Minas Gerais, Brazil. A number of remedial alternatives were evaluated. The USGS modular 3D finite difference groundwater
flow model (Modflow) and Modular 3D Finite Difference Mass Transport Model (MT3D) software were used to simulate groundwater
flow and contaminant transport modelling, as well as to predict changes due to the proposed remediation measures. The remedial
alternatives considered for normal conditions from 20 to 40 year periods were waste removal, vertical cut-off barriers, extraction
wells and top capping. The results indicated that extraction wells and waste removal are the best alternatives because they
significantly reduce both the extension and levels of the contamination plume even after 5 years. The extraction well proved
a less expensive remedial alternative than waste removal.
相似文献
38.
O Parra N García-Esclasans JM Montserrat L García Eroles J Ruíz JA López JM Guerra JJ Sope?a 《Canadian Metallurgical Quarterly》1997,10(8):1720-1724
The purpose of this study was to analyse the validity and the economic efficiency of a portable monitor of respiratory parameters (PMRP), used in a home setting for the diagnosis of sleep apnoea/hypopnoea syndrome (SAHS). Eighty nine patients with suspected SAHS were studied in two settings: in the sleep laboratory using full-polysomnography (full-PSG); and at the patient's home using a PMRP. In the home setting, 50 patients were assisted by a technician and 39 set up the equipment themselves. SAHS (apnoea/hypopnoea index (AHI) >10 events x h(-1) by means of full-PSG) was diagnosed in 75 of the 89 patients. An acceptable agreement was obtained between the AHI measured by full-PSG and PMRP, according to the Bland and Altman method of concordance (mean bias 2.56; 95% confidence interval 3.25). Sensitivity and specificity of PMRP were adequate for diagnostic purposes; however, their values rely on the prior PMRP-AHI cut-off point selected with reference to full-PSG-AHI >10. The clinical therapeutic decision taken after PMRP agreed with that taken with full-PSG in 79 patients (89%). Although 10% of the studies with an individual set-up needed repetition, both of the domiciliary modalities (with and without a technician's intervention) were, economically, about three times more efficient than full-PSG. In conclusion, we believe that patients with a suspected sleep apnoea/hypopnoea syndrome should initially be studied in a home setting with a portable monitor of respiratory parameters, since it is a reliable method with an acceptable cost-effective profile. 相似文献
39.
Comparisons of Urban Travel Forecasts Prepared with the Sequential Procedure and a Combined Model 总被引:4,自引:1,他引:3
Justin D. Siegel Joaquín De Cea José Enrique Fernández Renán E. Rodriguez David Boyce 《Networks and Spatial Economics》2006,6(2):135-148
Detailed analyses and comparisons of urban travel forecasts prepared by applying the state-of-practice sequential procedure
and the solution of a combined network equilibrium model are presented. The sequential procedure for solving the trip distribution,
mode choice and assignment problems with feedback is the current practice in most transportation planning agencies, although
its important limitations are well known. The solution of a combined model, in contrast, results from a single mathematical
formulation, which ensures a well-converged and consistent result. Using a real network, several methods for solving the sequential
procedure with feedback are compared to the solution of the combined model ESTRAUS. The results of these methods are shown
to have various levels of instability. The paper concludes with a call for a new paradigm of travel forecasting practice based
on an internally consistent model formulation that can be solved to a level of precision suitable for comparing alternative
scenarios. 相似文献
40.
Jos A. Grimbergen Koen Visscher Daniel S. Gomes De Mesquita G. J. Brakenhoff 《Yeast (Chichester, England)》1993,9(7):723-732
Individual yeast cells can be successfully isolated and recultured on plates with a new isolation method making use of optical trapping with infrared laser light. The cells can be selected on morphological criteria by high resolution microscopy. The isolation device is constructed from two coverslips separated by spacers, in which selected cells are transferred to a plastic capillary, using the optical trap. To test the procedure, selection experiments were done with a mixture of two Saccharomyces cerevisiae strains, distinguishable both in fluorescence microscopy and on agar plates. These experiments showed that only selected cells were isolated, and close to 100% of the isolated stationary-phase cells formed colonies on agar plates, indicating a high recovery. A lower recovery was obtained with exponential-phase cells, possibly because of a higher sensitivity to laser irradiation. Applications for this method may include the isolation of mutants with altered morphology and the isolation of subpopulations of yeast cultures, for their separate investigation or for the initiation of pure cultures. 相似文献