Photochemistry of α,α′-Disubstituted Azoalkanes. I. Photosolvolytic Inversion and Substitution of α,α′-Dichloro- and α,α′-Dialkoyloxyazoalkanes

A series of α,α′-dichloro (α DClA), α,α′-dialkoyloxy- (αDAlA) and α,α′-dibenzoxy-azoalkanes (αDBeA) without α-aryl substituents was found to undergo meso ? dl photointerconversion upon direct irradiation through Pyrex in the presence of oxygen in a number of solvents. Furthermore, irradiation of α,α′-dipropionoxy-azoalkanes in benzene in the presence of excess acetic acid leads to substitution of the propionoxy groups by acetoxy groups in addition to meso ? dl photointerconversion. Similar irradiation in the presence of CH₃CO₂D does not lead to deuterium substitution of the β-hydrogens. The presence of benzenethiol radical scavenger does not affect the course of these photoreactions. Photosolvolysis schemes involving heterolysis (in the case of αDAlA and αDBeA) or an unstable intermediate (in the case of αDClA) are proposed.     

Efficient Set Intersection with Simulation-Based Security

We consider the problem of computing the intersection of private datasets of two parties, where the datasets contain lists of elements taken from a large domain. This problem has many applications for online collaboration. In this work, we present protocols based on the use of homomorphic encryption and different hashing schemes for both the semi-honest and malicious environments. The protocol for the semi-honest environment is secure in the standard model, while the protocol for the malicious environment is secure in the random oracle model. Our protocols obtain linear communication and computation overhead. We further implement different variants of our semi-honest protocol. Our experiments show that the asymptotic overhead of the protocol is affected by different constants. (In particular, the degree of the polynomials evaluated by the protocol matters less than the number of polynomials that are evaluated.) As a result, the protocol variant with the best asymptotic overhead is not necessarily preferable for inputs of reasonable size.     

A ‘Natural Logic’ inference system using the Lambek calculus

This paper develops an inference system for natural language within the ‘Natural Logic’ paradigm as advocated by van Benthem (1997), Sánchez (1991) and others. The system that we propose is based on the Lambek calculus and works directly on the Curry-Howard counterparts for syntactic representations of natural language, with no intermediate translation to logical formulae. The Lambek-based system we propose extends the system by Fyodorov et~al. (2003), which is based on the Ajdukiewicz/Bar-Hillel (AB) calculus Bar Hillel, (1964). This enables the system to deal with new kinds of inferences, involving relative clauses, non-constituent coordination, and meaning postulates that involve complex expressions. Basing the system on the Lambek calculus leads to problems with non-normalized proof terms, which are treated by using normalization axioms.     

Physics of perpendicular recording with a patterned soft underlayer

In this paper, it is argued that perpendicular recording in the most popular current form--with the use of a continuous soft underlayer (SUL)--may not be the most optimal way to maximize the achievable areal density. As a possible solution, patterning of SUL is discussed. The purpose of patterning of a SUL is to effectively move the image head closer to the recording media, as compared to the real recording head, and thus increase the net recording field and the field gradient across the thickness of the media. Various patterning configurations and combinations with recording layers are comparatively studied. It is illustrated that with a patterned SUL, the recording and sensitivity fields, responsible for writing and reading information, respectively, could be not only increased by several factors but also localized across the entire thickness of the recording media.     

Aetiology of intramammary infection and its effect on milk composition in goat flocks

Although there has been little study of the origin of intramammary infection (IMI) in goats, a common view is that most bacterial infection in goats occurs during milking. In the present study, the dynamics of occurrence of udder infection during and between lactations in three Anglo-Nubian goat farms in Israel was monitored. Coagulase-negative staphylococci were the predominant bacteria in the IMIs. We found that about 15% of the yearling does were already infected with bacteria when they joined the flock, whereas about 8% of the goats that dried-off returned with new IMIs. Moreover, virtually none of the goats acquired infection during lactation. Thus, our study showed that the aetiology of IMI in goats is very similar to that in dairy cows. A preventive treatment during the dry period should, therefore, be considered as an effective means of reducing the current rate of bacterial infections in goats.     

一种实用的磷化铟MMIC背面工艺技术

采用湿法技术发展了磷化铟 MMIC的背面通孔刻蚀工艺 ,PMMA用作粘片剂 ,In P衬底粘附于玻璃版上 ,溅射钽膜用作湿法刻蚀掩膜 ,HCl+H3PO4 腐蚀液实现 10 0 μm的通孔腐蚀 .已证实这种湿法通孔工艺宽容度大 ,精确可控     

一种实用的磷化铟MMIC背面工艺技术

采用湿法技术发展了磷化铟MMIC的背面通孔刻蚀工艺,PMMA用作粘片剂,InP衬底粘附于玻璃版上,溅射钽膜用作湿法刻蚀掩膜,HCl+H3PO4腐蚀液实现100μm的通孔腐蚀.已证实这种湿法通孔工艺宽容度大,精确可控.     

A triple channel HEMT on InP (Camel HEMT) for large-signalhigh-speed applications

A triple channel HEMT structure grown on InP has been developed (the “Camel” HEMT). Starting from a dual channel (InGaAs/InP) HEMT that utilizes both the high electron mobility of InGaAs and the low impact ionization coefficient of InP, a third InGaAs channel as well as a quaternary carrier supply layer have been introduced to improve the electron transfer and thus the transistor performance. The design of the new transistor structure and its fabrication technology are described. Static and dynamic performances for an 0.8 μm gate length Camel HEMT are presented and compared to standard double channel HEMT transistors that are fabricated with the same geometry and process conditions. The results show that this new structure offers a very good tradeoff between high breakdown voltage and current gain cutoff frequency     

Characterization of a branched-chain amino-acid aminotransferase from Schizosaccharomyces pombe

The Saccharomyces cerevisiae genes for the cytosolic and mitochondrial branched-chain amino-acid aminotransferases (BCAT) were isolated recently. These genes show significant homology to mammalian ECA39, originally isolated as a gene regulated by the c-myc oncogene. We now report the isolation of the Schizosaccharomyces pombe eca39/BCAT gene. The S. pombe protein shows 47–52% identity to other eukaryotic BCAT proteins isolated from S. cerevisiae, nematode, mouse and man. A genetic growth assay for BCAT activity was established using an S. cerevisiae strain disrupted in both BCAT isoenzymes. Consequently, the activity of the S. pombe BCAT was demonstrated by genetic and biochemical means. Possible applications of BCAT-encoding genes as selection markers in yeast transformation are proposed. The sequence has been deposited in the GenBank data library under Accession Number U88029. © 1998 John Wiley & Sons, Ltd.     

Enhanced percutaneous permeability of diclofenac using a new U-type dilutable microemulsion

Enhanced systemic absorption in vivo and percutaneous penetration in vitro was demonstrated after transdermal administration of diclofenac sodium formulated in U-type microemulsion. Diclofenac sodium was solubilized in a typical four-component system consisting of an oil, polyoxyethylene-10EO-oleyl alcohol (Brij 96V) as the surfactant, and 1-hexanol along water dilution line W46 (40 wt % surfactant and 60 wt % oil phase before water titration).Viscosity and small angle X-ray scattering measurements have evidenced bicontinuous structures within water fractions of 0.25 and 0.5 along the dilution line. Self-diffusion NMR studies showed that drug molecules accumulated in the interfacial film and, to some extent, dissolved in the oil. Relative to a commercial macro-emulsion cream (Voltaren® Emulgel®), microemulsions containing paraffin oil or isopropyl myristate increased the in vivo transdermal penetration rate of diclofenac by two order of magnitude, whereas the rat plasma levels were increased by one order of magnitude. The in vitro data obtained from excised rat skin were comparable to the in vivo results, but suffered from discrepancies from the ideal in vivo-in vitro correlation, which might be explained by optimal in vitro conditions of perfusion and hydration. It has also been found that when jojoba oil is formulated as the oil phase in the microemulsion, the penetration rate of the drug decreases significantly. Based on the three-dimensional structure of jojoba oil, the wax is presumed to prevent the drug from being freely diffused into the skin while migrating from the interfacial film into the continuous oil phase.