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21.
Satbir Singh Peter J. Adams Ashwin Misquitta Kyung J. Lee Eric M. Lipsky Allen L. Robinson 《Aerosol science and technology》2014,48(6):638-648
Measurement of fine particle emission from combustion sources is important to understand their health effects, and to develop emissions regulations. Dilution sampling is the most commonly used technique to measure particle number distribution because it simulates the mixing and cooling of combustion exhaust with atmospheric air, which drives nucleation and condensation of semi volatile material. Experiments suggest that the measured size distribution is dependent on the dilution ratio used and the tunnel design. In the present work, computational analysis using a large-eddy-simulation (LES) based model is performed to investigate the effect of tunnel flow and geometric parameters on H2SO4-H2O binary nucleation inside dilution tunnels. Model predictions suggest that the experimental trends are likely due to differences in the intensity of turbulent mixing inside the tunnels. It is found that the interaction of dilution air and combustion exhaust in the mixing layer greatly impacts the extent of nucleation. In general, a cross-flow interaction with enhanced turbulent mixing leads to greater number of nucleation-mode particles than an axial-flow interaction of combustion sample and dilution air.
Copyright 2014 American Association for Aerosol Research 相似文献
22.
The design and fabrication of complex nanostructures with specific geometry and composition is one of the main challenges of nanotechnology. Here we demonstrate the devise of metal-insulator-metal, trilayered, coaxial nanocables. Such coaxial geometry may give rise to useful and unique electromagnetic properties. We have fabricated these nanostructures using a scaffold of self-assembled peptide nanotubes. Gold nanoparticles were bound to the surface of peptide nanotubes via a common molecular recognition element that was included in various linker peptides. This enabled us to promote site-specific metal reduction and to create the coaxial nanostructure. Using electron microscopy, 1H NMR spectra, and energy-dispersive X-ray analysis, we monitored the different steps within the process, gaining further understanding of its mechanism. 相似文献
23.
Shrivastava MK Lipsky EM Stanier CO Robinson AL 《Environmental science & technology》2006,40(8):2671-2677
Experimental measurements of gas-particle partitioning and organic aerosol mass in diluted diesel and wood combustion exhaust are interpreted using a two-component absorptive-partitioning model. The model parameters are determined by fitting the experimental data. The changes in partitioning with dilution of both wood smoke and diesel exhaust can be described by two lumped compounds in roughly equal abundance with effective saturation concentrations of approximately 1600 microg m(-3) and approximately 20 microg m(-3). The model is used to investigate gas-particle partitioning of emissions across a wide range of atmospheric conditions. Under the highly dilute conditions found in the atmosphere, the partitioning of the emissions is strongly influenced by the ambient temperature and the background organic aerosol concentration. The model predicts large changes in primary organic aerosol mass with varying atmospheric conditions, indicating that it is not possible to specify a single value for the organic aerosol emissions. Since atmospheric conditions vary in both space and time, air quality models need to treat primary organic aerosol emissions as semivolatile. Dilution samplers provide useful information about organic aerosol emissions; however, the measurements can be biased relative to atmospheric conditions and constraining predictions of absorptive-partitioning models requires emissions data across the entire range of atmospherically relevant concentrations. 相似文献
24.
EC Van Os JA McKinney BJ Zins DC Mays ZH Schriver WJ Sandborn JJ Lipsky 《Canadian Metallurgical Quarterly》1996,679(1-2):147-154
We investigated whether linear whole-body acceleration along the interaural y-axis influenced the concurrent perception of visual motion direction as has been shown for angular accelerations. A sled running on air bearings along a 7.5-m track was used to accelerate 18 subjects at two different linear accelerations. These young, healthy volunteers, aged 25.50 +/- 7.38 years, used a joystick to indicate whether or not they perceived visual motion to the left within a random-dot kinematogram continuously presented on a monitor moving with them. The percentage of coherently leftward moving pixels presented for a 640-ms period during acceleration was adjusted according to a Modified Binary Search (MOBS) procedure. Six conditions were tested, two acceleration levels of 1 and 2 m/s2 to both left and right with, at the higher acceleration, two different times of visual motion presentation. Conditions were sequenced by means of a 6 x 6 Latin square balanced for order and carry over. A MANOVA did not show any statistically significant effects either for the independent variables acceleration, velocity, and direction of motion of the sled or for their interactions. The results obtained are in clear contrast to those obtained under rotatory stimulation. We conclude that the otolithic contribution to vestibular-visual motion processing is negligible. 相似文献
25.
Daniel Geist Mark Ginzburg Yoad Lustig Ishai Rabinovitz Ohad Shacham Rachel Tzoref 《Electronic Notes in Theoretical Computer Science》2006,144(1):67
The standard translation of a Bounded Model Checking (BMC) instance into a satisfiability problem, (a.k.a SAT), might produce misleading results in the case when the model under verification contains finite paths. Models with finite paths might be produced unknowingly when using modern verification languages such as PSL-Sugar [Property Specification Language: Reference Manual. Version 1.1, Accellera, June 2004]. Specifically, the use of language constructs such as restrict, assume etc. might lead to such models. Thus the user may receive misleading results from SAT based tools.In this paper we describe in what circumstances the finite path problem occurs and present an improved translation of the BMC problem into a SAT instance. The new translation does not suffer from the discussed shortcoming. Our translation is only slightly longer then the usual one introducing one extra Boolean variable in the model.We also show that this translation may improve the SAT solver runtime even for models without finite paths. 相似文献
26.
H Lipsky 《Canadian Metallurgical Quarterly》1976,15(5):207-212
Thirty women presenting with urethral syndrome were investigated. A full urologic, radiologic, gynecologic and urodynamic assessment was carried out. In most patients the cause of their troubles was found. In 19 of them an obstruction was demonstrated. Two types of obstruction were seen: The first occurred mainly in postmenopausal women. Here, a narrow distal segment of the urethra was demonstrated. The second type of obstruction was seen mainly in younger patients. The cause was an incomplete relaxation or a spasm of the external striated sphincter. Other causes of symptoms were instability and atony of the detrusor. In some women no cause for their symptoms and recurrent urinary infection was found. 相似文献
27.
Below the thresholds for production of He+ in the N = 2 and N = 3 states the doubly-excited states in isoelectronic helium (Z = 1, 2, 3, 4, 5) have been completely classified as to series and outer quantum number by means of calculations using the truncated diagonalization method with hydrogenic basis functions. The classifications, energy levels, and effective quantum numbers are tabulated here for all systems with total orbital angular momentum L = 0, 1, 2, 3. 相似文献
28.
HP Brezinschek SJ Foster T D?rner RI Brezinschek PE Lipsky 《Canadian Metallurgical Quarterly》1998,160(10):4762-4767
A functional Ig consists of two heterodimers each of which is composed of a heavy and a light chain. Although there is increasing knowledge about the events that govern the rearrangement of the genes encoding each individual chain, only very limited information is available about the mechanisms governing the pairing of variable heavy (V(H)) and variable light (V(L)) chains. Using a single cell PCR, we were able to obtain V(H) and Vkappa chains from 144 individual human CD19+/IgM+ B cells. Pairing of specific V(H) or Vkappa families was not observed, nor was the length or the amino acid composition of the CDR3s of V(H) and Vkappa chains in individual B cells similar. Comparison of V(H) and Vkappa genes in B cells in which one or both contained evidence of somatic hypermutation with those with no mutations revealed a significant decrease in the mean length of the V(H) CDR3. Moreover, there was a significant correlation between the frequencies of mutations in V(H) and Vkappa gene pairs in individual B cells. These results indicate that Ag-mediated selection as opposed to V(H)DJ(H) recombination or subsequent Ig chain pairing tended to approximate the CDR3 lengths and the frequency of mutations of V(H) and Vkappa in individual B cells. 相似文献
29.
Staphylococcal protein A (SPA), HIV gp120, and staphylococcal enterotoxins (SE) are B cell superantigens that induce VH specific B cell responses. In addition, the red blood cell antigens, i/I, have some features of a B cell superantigen. Binding of SPA, SE and HIV gp120 are VH family specific, whereas binding of i/I is VH gene specific. SPA and HIV gp120 function by stimulating VH3-expressing B cells, whereas SE appear to function by enhancing survival of the appropriate VH-expressing B cells. Moreover, HIV gp120 has been shown to delete VH3-expressing B cells. In this review, we describe evidence that shows how these superantigens may play a role in shaping the normal B cell repertoire. 相似文献
30.
Wortmannin (WT) and 17beta-hydroxywortmannin (HWT), which are inhibitors of phosphatidylinositol-3(OH)-kinase (PI3K), have been shown previously to inhibit bone resorption in vitro and in vivo, possibly by interfering with formation of the osteoclast ruffled border. Since migration of osteoclasts also plays an important role in the process of bone resorption, we investigated the effects of these inhibitors on osteoclast morphology and motility. Both HWT and WT caused a sustained decrease in the planar area of osteoclasts in vitro (half maximal effect at 25 and 165 nM, respectively), with the effect of HWT on cell area more readily reversible than WT. These agents also caused accumulation of intracellular vesicles. Time-lapse video microscopy was used to record the migration of osteoclasts in response to macrophage colony-stimulating factor (M-CSF) or vehicle, flowing passively from a micropipette positioned 200-400 microm from the cell. M-CSF caused directed migration of osteoclasts, indicating chemotaxis (over 3 h osteoclasts migrated 96 +/- 14 microm in response to M-CSF vs. 11 +/- 2 microm in control experiments). Both WT (100 or 500 nM) and LY294002 (100 microM), a specific PI3K inhibitor structurally unrelated to WT, significantly inhibited osteoclast chemotaxis in response to M-CSF. Taken together, these effects of WT, HWT, and LY294002 are consistent with an important role for PI3K in regulating cytoskeletal function in osteoclasts. The inhibitory effects of WT and HWT on bone resorption may be due, in part, to impairment of osteoclast motility. 相似文献