用基于对象的Java中间件实现校园网网格计算

本文通过对校园网网格计算环境、计算的特殊性等的讨论,提出了通过Java中间件以构建“计算池”的方法来实现“校园网网格”,从而为我国高校构建自身的校园网网格提供了一个可供选择的实际方案。     

构建时延基因调控网络的多数据源融合算法

为了进一步提高基因调控网络构建的精确度,提出一种基于多数据源融合的时延基因调控网络构建算法.该算法基于递归模糊神经网络模型,使用时序互信息估计基因间的转录时延,并限制每个基因的潜在调控基因,从而有效提高建网的效率.在网络结构学习阶段,使用离散多目标粒子群优化(discrete multi-objective particle swarm optimization,dMOPSO)算法实现从时序基因表达数据和CHIP-chip数据共同构建基因调控网络.人工模拟数据和酵母菌细胞周期表达数据的实验结果表明该算法能正确选出潜在的调控基因,从而更加精确地构建基因调控网络.     

ULC：一种用户层通信协议的实现技术

ＵＬＣ是专为计算机群机计算而实现的用户层通信库。它在用户层提供了一个多用户,多线路的通信库,在用户层完成消息多路复用。多协议处理,硬件及关键区互销机制。     

隔震结构非线性随机地震响应分析的复模态法

本对多自由度双线性滞变隔震结构在过滤白噪声地震激励下的随机响应问题进行了系统研究。首先建立了结构非线性运动方程；然后根据非线性随机振动理论对运动方程进行等效线性化；最后用复模态法获得了等效线性方程的解析解，将复杂的非线性随机响应问题简化为求解一元非线性代数方程问题，并给出了算例。从而建立了多自由度隔震结构非线性随机响应复模态分析的一整套计算方法。     

HTRA1 Regulates Subclinical Inflammation and Activates Proangiogenic Response in the Retina and Choroid

High-temperature requirement A1 (HtrA1) has been identified as a disease-susceptibility gene for age-related macular degeneration (AMD) including polypoidal choroidal neovasculopathy (PCV). We characterized the underlying phenotypic changes of transgenic (Tg) mice expressing ubiquitous CAG promoter (CAG-HtrA1 Tg). In vivo imaging modalities and histopathology were performed to investigate the possible neovascularization, drusen formation, and infiltration of macrophages. Subretinal white material deposition and scattered white-yellowish retinal foci were detected on CFP [(Tg—33% (20/60) and wild-type (WT)—7% (1/15), p < 0.05]. In 40% (4/10) of the CAG-HtrA1 Tg retina, ICGA showed punctate hyperfluorescent spots. There was no leakage on FFA and OCTA failed to confirm vascular flow signals from the subretinal materials. Increased macrophages and RPE cell migrations were noted from histopathological sections. Monocyte subpopulations were increased in peripheral blood in the CAG-HtrA1 Tg mice (p < 0.05). Laser induced CNV in the CAG-HtrA1 Tg mice and showed increased leakage from CNV compared to WT mice (p < 0.05). Finally, choroidal explants of the old CAG-HtrA1 Tg mice demonstrated an increased area of sprouting (p < 0.05). Signs of subclinical inflammation was observed in CAG-HtrA1 Tg mice. Such subclinical inflammation may have resulted in increased RPE cell activation and angiogenic potential.     

TD-SCDMA 直放站无线通信控制方案开发与实现

在TD—SCDMA系统中,直放站实现低成本的室内覆盖和减少信号盲区,是不可或缺的一部分。直放站系统要通过无线通信模块进行控制信息的交互,无线通信控制方案的实现是直放站系统开发中极为重要的一环。基于成熟的TD—SCDMA终端基带芯片的直放站无线通信控制方案,需要对硬软件配置做出相应的调整。通信控制方案中一个重要环节就是协定无线通信模块与直放站监控系统的串口通信接口,设计串口通信软件模块,串口通信协议的设定后,就可以经济、并快速地完成无线通信控制方案的实现。     

CAN通信机理剖析及MCF52235FlexCAN底层驱动构件的开发

基于CAN(Control Area Network)硬件原理模型,深入剖析了CAN总线的仲裁、应答及报文过滤机制等通信机理,提出了CAN总线简化硬件电路设计。以此为基础,对Freescale MCF52235的FlexCAN模块底层驱动的封装方法进行了分析研究,根据嵌入式软件工程原则,给出了满足移植与复用要求的FlexCAN构件设计,为同类应用提高开发效率、增强系统稳定性提供了技术支持。通过应用实例给出了使用FlexCAN构件建立CAN通信网络的实现方法。     

实时协同中的一致性维护关键技术

实时协同广泛采用数据复制技术来隐藏网络延迟、提高响应速度和改善交互体验。在复制式结构中,用户可以无约束地在不同数据副本上进行操作,这必然会引发一致性维护问题。针对上述问题,根据实时协同应用的特点和需求,总结一致性维护研究面临的技术挑战,通过研究实时协同中操作转换、地址空间转换和WOOT一致性维护的关键技术,讨论Undo和String转换等难点问题,分析这些关键技术在单用户软件向多用户协同软件透明转换、Web2.0环境和移动协同环境中的应用情况。     

高层建筑TMD风振控制分析的复模态法

本文对带TMD的高层建筑风振响应问题进行了系统研究。首先建立了运动方程，然后用第一振型将主体结构展开，针对所得方程为非经典阻尼和非对称结构以及脉动风谱为非有理分式风谱的情况，用线性滤波过程生成脉动风谱，用复模态理论和扩阶法进行解耦，获得了等效风谱对应的以第一振型表示的结构风振响应的解析解。本文方法可用于带TMD结构的风振与抗风可靠度分析以及基于可靠度约束的抗风优化设计。     

In vitro metabolic N- and C-oxidation of phenanthridine

In order to compare an acceleromyograph (TOF-Guard) with a mechanomyograph (Grass FT03), the dose-response relationship of rocuronium was simultaneously determined in both arms of 15 children aged 3-11 years during anaesthesia with thiopentone, alfentanil and nitrous oxide. Three subgroups of five children received rocuronium 120, 180 or 240 micrograms.kg-1 randomly. The effective doses to produce 50% and 95% depression of the first twitch of the train-of-four determined by acceleromyography were 206 and 337 micrograms.kg-1, respectively, while these values determined by mechanomyography were 151 and 331 micrograms.kg-1, respectively. The dose-response curve obtained by acceleromyography was steeper and shifted to the right compared with that obtained by mechanomyography (p < 0.0001). The difference between the effective dose producing 50% twitch depression determined by the two devices was highly significant (p < 0.0001). In 13 out of 15 children, the acceleromyograph control train-of-four ratio was significantly greater than unity. Although there was a good correlation (r = 0.85) between simultaneous pairs of measurements of neuromuscular block, the acceleromyograph exhibited a bias of -25% relative to the mechanomyograph with wide limits of agreement (-62 to +12%). We conclude that acceleromyographic and mechanomyographic measurements should not be used interchangeably when determining the potency of muscle relaxants.