Evaluation of the effect of a paver’s trolley on productivity, task demands, workload and local discomfort

The objective of this study was to determine the differences in the number of paving stones laid (productivity), task demands, energetic workload, body region discomfort and preference when laying paving stones with or without use of a paver’s trolley (n = 8) in a within-subject controlled study of pavers. The number of paving stones laid and the task demands were measured by means of systematic observations at the workplace. The energetic workload was determined using the percentage of heart rate reserve (%HRR). Body region discomfort was measured using visual analog scales, and the workers’ preference was ascertained via interview. The use of a paver’s trolley had no effect on productivity, %HRR or body region discomfort compared to working without a paver’s trolley. The duration of knee-straining activities did not differ between working with (141 min) and without (146 min) the paver’s trolley. However, six of the eight pavers indicated that, given suitable circumstances, they wanted to use the paver’s trolley.

Relevance to industry

To reduce the chance of work-related low back and knee complaints among pavers, the duration, frequency and intensity of lower back and knee-straining activities should be limited by means of technical measures such as mechanical paving. The paver’s trolley does not appear to reduce knee-straining activities and therefore does not appear useful in reducing the risk of knee complaints and disorders.     

Integrating working and enrichment approach learning: a document

Integrating working and learning is seen as a desirable alternative to traditional training regimes. An integrated approach to working and learning is more gradual, contextual, problem oriented and cost effective. Knowledge technology aims to catalyze workplace learning, but requires the right organisational culture and brings additional costs regarding the articulation, representation and transmission of knowledge. Our approach reduces these costs by making articulation a natural part of collaborative working, designing for both informal and formal knowledge, and facilitating the transition of socially situated knowledge through enriched documents. To be successful, our approach has certain prequesites concerning organisational culture, and the nature of shared documents, organisational knowledge and work activities.     

A quantum chemical study of the mechanism of action of Vitamin K epoxide reductase (VKOR) II. Transition states

A reaction path including transition states is generated for the Silverman mechanism [R.B. Silverman, Chemical model studies for the mechanism of Vitamin K epoxide reductase, J. Am. Chem. Soc. 103 (1981) 5939-5941] of action for Vitamin K epoxide reductase (VKOR) using quantum mechanical methods (B3LYP/6-311G**). VKOR, an essential enzyme in mammalian systems, acts to convert Vitamin K epoxide, formed by Vitamin K carboxylase, to its (initial) quinone form for cellular reuse. This study elaborates on a prior work that focused on the thermodynamics of VKOR [D.W. Deerfield II, C.H. Davis, T. Wymore, D.W. Stafford, L.G. Pedersen, Int. J. Quant. Chem. 106 (2006) 2944-2952]. The geometries of proposed model intermediates and transition states in the mechanism are energy optimized. We find that once a key disulfide bond is broken, the reaction proceeds largely downhill. An important step in the conversion of the epoxide back to the quinone form involves initial protonation of the epoxide oxygen. We find that the source of this proton is likely a free mercapto group rather than a water molecule. The results are consistent with the current view that the widely used drug Warfarin likely acts by blocking binding of Vitamin K at the VKOR active site and thereby effectively blocking the initiating step. These results will be useful for designing more complete QM/MM studies of the enzymatic pathway once three-dimensional structural data is determined and available for VKOR.     

Effect of interface on the mechanical behaviour of glass bead-filled PVC

The surface of glass beads of average particle size 100m was modified (a) by incorporating extra hydroxyl groups by chemcial treatment, and (b) by applying a thin coating of polymethacrylic acid (PMA) on the glass surface. The corresponding chemical changes were investigated using infrared spectroscopy. The tensile behaviour of a glass bead-filled PVC composite prepared with surface-modified glass beads, showed the following effects: (a) hydroxyl groups incorporated on to the glass surface did not affect the glass-PVC interface and hence did not change the tensile behaviour of the composite; (b) PMA coating on the glass surface caused improvement in the tensile behaviour in the low strain region and deterioration in the high region. An SEM study of the fractured surface suggested debonding at the glass-PVC interface in the first case, and failure of the PVC-PMA interface in the second case.     

Phytoplankton Productivity and Standing Crop in the Vicinity of the Lake Huron-Saginaw Bay Front

Continuous underway sampling was used in four research cruises near the mouth of Saginaw Bay in order to locate the bay-lake front, where eutrophic bay water mixes with oligotrophic Lake Huron water. Although mixing between these water masses normally occurs in outer Saginaw Bay, the distribution was variable, depending on wind force and direction as well as water temperature. Large algal crops in inner Saginaw Bay had reduced soluble nutrients, particularly silicate and nitrate-nitrogen, in the outer bay to levels lower than the adjacent lake water. Nonetheless, outer bay water supported high algal biomass (up to 14 μg/L chlorophyll a) and ¹⁴C uptake (up to 73 μg /L/h). The phytoplankton community at the nutrient front between bay and lake waters was characterized by high chlorophyll a biomass ($\overline{x}$ = 4.47 μg/L), low ¹⁴C uptake ($\overline{x}$ = 7.12 μg/L/h), and high bacterial activity (V_max$\overline{x}$ = 1.33) indicating the presence of a senescent assemblage. Decomposition and settling of phytoplankton in the vicinity of the front apparently served to remove much of the bay plankton from the water column before mixing into the open lake. But, during mid-summer, occasional large inputs of nutrients and/or phytoplankton from the bay into the open lake were observed.     

The use of NDVI and its Derivatives for Monitoring Lake Victoria’s Water Level and Drought Conditions

Normalized Difference Vegetation Index (NDVI), which is a measure of vegetation vigour, and lake water levels respond variably to precipitation and its deficiency. For a given lake catchment, NDVI may have the ability to depict localized natural variability in water levels in response to weather patterns. This information may be used to decipher natural from unnatural variations of a given lake’s surface. This study evaluates the potential of using NDVI and its associated derivatives (VCI (vegetation condition index), SVI (standardised vegetation index), AINDVI (annually integrated NDVI), green vegetation function (F _g ), and NDVIA (NDVI anomaly)) to depict Lake Victoria’s water levels. Thirty years of monthly mean water levels and a portion of the Global Inventory Modelling and Mapping Studies (GIMMS) AVHRR (Advanced Very High Resolution Radiometer) NDVI datasets were used. Their aggregate data structures and temporal co-variabilities were analysed using GIS/spatial analysis tools. Locally, NDVI was found to be more sensitive to drought (i.e., responded more strongly to reduced precipitation) than to water levels. It showed a good ability to depict water levels one-month in advance, especially in moderate to low precipitation years. SVI and SWL (standardized water levels) used in association with AINDVI and AMWLA (annual mean water levels anomaly) readily identified high precipitation years, which are also when NDVI has a low ability to depict water levels. NDVI also appears to be able to highlight unnatural variations in water levels. We propose an iterative approach for the better use of NDVI, which may be useful in developing an early warning mechanisms for the management of lake Victoria and other Lakes with similar characteristics.