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21.
This paper deals with the weight minimization of planar steel trusses by adopting a differential evolution-based algorithm. Square hollow sections are considered. The design optimization refers to size, shape and topology. The design variables are represented by the geometrical dimensions of the cross sections of the different components of the truss, directly involving the size of the structure, and by some geometrical parameters affecting the outer shape of the truss. The topology is included in the optimization search in a particular way, since the designer at different runs of the algorithm can change the number of bays keeping constant the total length of the truss, to successively choose the best optimal solution. The minimum weight optimum design is posed as a single-objective optimization problem subject to constraints formulated in accordance with the current Eurocode 3. The optimal solution is obtained by a Differential Evolutionary (DE) algorithm. In the DE algorithm, a particular combination of mutation and crossover operators is adopted in order to achieve the best solutions and a specific way for dealing with constraints is introduced. The effectiveness of the proposed approach is shown with reference to two case-studies. The analysis results prove the versatility of the optimizer algorithm with regard to the three optimization categories of sizing, shape, topology as well as its high computational performances and its efficacy for practical applications. In particular useful practical indications concerning the geometrical dimensions of the various involved structural elements can be deduced by the optimal solutions: in a truss girder the cross section of the top chord should be bigger than the one of the bottom chord as well as diagonals should be characterized by smaller cross sections with respect to the top and bottom chords in order to simultaneously optimize the weight and ensure an optimal structural behaviour.  相似文献   
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Objective

Current magnetic resonance imaging (MRI) axon diameter measurements rely on the pulsed gradient spin-echo sequence, which is unable to provide diffusion times short enough to measure small axon diameters. This study combines the AxCaliber axon diameter fitting method with data generated from Monte Carlo simulations of oscillating gradient spin-echo sequences (OGSE) to infer micron-sized axon diameters, in order to determine the feasibility of using MRI to infer smaller axon diameters in brain tissue.

Materials and methods

Monte Carlo computer simulation data were synthesized from tissue geometries of cylinders of different diameters using a range of gradient frequencies in the cosine OGSE sequence . Data were fitted to the AxCaliber method modified to allow the new pulse sequence. Intra- and extra-axonal water were studied separately and together.

Results

The simulations revealed the extra-axonal model to be problematic. Rather than change the model, we found that restricting the range of gradient frequencies such that the measured apparent diffusion coefficient was constant over that range resulted in more accurate fitted diameters. Thus a careful selection of frequency ranges is needed for the AxCaliber method to correctly model extra-axonal water, or adaptations to the method are needed. This restriction helped reduce the necessary gradient strengths for measurements that could be performed with parameters feasible for a Bruker BG6 gradient set. For these experiments, the simulations inferred diameters as small as 0.5 μm on square-packed and randomly packed cylinders. The accuracy of the inferred diameters was found to be dependent on the signal-to-noise ratio (SNR), with smaller diameters more affected by noise, although all diameter distributions were distinguishable from one another for all SNRs tested.

Conclusion

The results of this study indicate the feasibility of using MRI with OGSE on preclinical scanners to infer small axon diameters.
  相似文献   
24.

Objective

Simultaneous modeling of true 2-D spectroscopy data, or more generally, interrelated spectral datasets has been described previously and is useful for quantitative magnetic resonance spectroscopy applications. In this study, a combined method of reference-lineshape enhanced model fitting and two-dimensional prior-knowledge fitting for the case of diffusion weighted MR spectroscopy is presented.

Materials and methods

Time-dependent field distortions determined from a water reference are applied to the spectral bases used in linear-combination modeling of interrelated spectra. This was implemented together with a simultaneous spectral and diffusion model fitting in the previously described Fitting Tool for Arrays of Interrelated Datasets (FiTAID), where prior knowledge conditions and restraints can be enforced in two dimensions.

Results

The benefit in terms of increased accuracy and precision of parameters is illustrated with examples from Monte Carlo simulations, in vitro and in vivo human brain scans for one- and two-dimensional datasets from 2-D separation, inversion recovery and diffusion-weighted spectroscopy (DWS). For DWS, it was found that acquisitions could be substantially shortened.

Conclusion

It is shown that inclusion of a measured lineshape into modeling of interrelated MR spectra is beneficial and can be combined also with simultaneous spectral and diffusion modeling.
  相似文献   
25.
A kind of magnetic field sensor (MFS) using a two-dimensional (2D) magnetic photonic crystal (MPC) slab waveguide as the sensing structure is proposed and investigated numerically. The slab structure is based on bismuth iron garnet (BIG), a well-known magnetic material with effective magnetooptical (MO) properties, sandwiched with gadolinium gallium garnet (GGG) as substrate. The complete photonic bandgap (PBG) of the 2D MPC is simulated and optimized for realization of polarization-independent waveguides. The simulation results show that the width and position of the complete PBG depend on the thickness of the BIG slab and the radius of the air holes used in the design. By reducing the lightwave propagation losses and enhancing the mode conversion ratio, increased sensitivity is obtained. Based on the Faraday effect, a good linear relationship is observed between the normalized output light intensity and the magnetic field strength as the gyrotropy parameter g is varied from 0.13 to 0.19, a g-range used as the sensor dynamic range. The remarkable enhancement in sensing performance due to the MO effect makes the designed device suitable for magnetic field sensing. The results are discussed to provide a basis for investigation of 2D MPC slab waveguides based on the same structure, which are of particular interest for development of highly sensitive MFSs.  相似文献   
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Hendrick Berlage is known to architectural history mainly for his Amsterdam Stock Exchange of 1903. This is often celebrated as a proto-modernist work in a rationalist spirit, an oversimplified view, for the building had a conventionally eclectic start and was the fruit of long struggle and many revisions. The development of Berlage's architectural ideas during the period of its gestation is chronicled in a fascinating way by a series of private villas built for friends who were artists and intellectuals. Completed year by year, they run right through the 1890s, showing Berlage's changing concerns with the articulation of content, the expression of construction, the application of controlling geometry, and the development of architectural space.  相似文献   
30.
Abstract

PLAN FOR REZONING THE CITY OF NEW YORK. A Report by Harrison, Ballard &; Allen. City Planning Commission. New York. 1950. 290 pp. maps, illustrations. $2.00.

CONTROLLED ACCESS EXPRESSWAYS IN URBAN AREAS—A symposium. Highway Research Board Bulletin No. 25. Washington, D. C., 1950. 45 pages, illustrated. 60 cents.

SOCIAL PRESSURES IN INFORMAL GROUPS. By Leon Festinger, Stanley Schachter and Kurt Back. Harper Bros., New York, 1950. x-930 pp. $3.00.

PRODUCTION OF NEW HOUSING. A Research Monograph on Efficiency in Production. By Leo Grebler. Social Science Research Council. New York 1950. ix+ 186 pp. $1.75.  相似文献   
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