ODTLES: A multi-scale model for 3D turbulent flow based on one-dimensional turbulence modeling

A novel multi-scale approach for extending the one-dimensional turbulence (ODT) model of [A.R. Kerstein. One-dimensional turbulence: model formulation and application to homogeneous turbulence, shear flows, and buoyant stratified flows, J. Fluid Mech. 392 (1999) 277] to treat turbulent flow in three-dimensional (3D) domains is described. In this model, here called ODTLES, 3D aspects of the flow are captured by embedding three, mutually orthogonal, one-dimensional ODT domain arrays within a coarser 3D mesh. The ODTLES model is obtained by developing a consistent approach for dynamically coupling the different ODT line sets to each other and to the large scale processes that are resolved on the 3D mesh. The model is implemented computationally and its performance is tested by performing simulations of decaying isotropic turbulence at two different Reynolds numbers and comparing to the experimental data of [H. Kang, S. Chester, C. Meneveau. Decaying turbulence in an active-grid-generated flow and comparisons with large-eddy simulations, J. Fluid Mech. 480 (2003) 129; G. Comte-Bellot, S. Corrsin, Simple Eulerian correlation of full-and narrow band velocity signals in grid-generated ’isotropic’ turbulence, J. Fluid Mech. 48 (1971) 273].     

Morphing active contours

A method for deforming curves in a given image to a desired position in a second image is introduced. The algorithm is based on deforming the first image toward the second one via a partial differential equation (PDE), while tracking the deformation of the curves of interest in the first image with an additional, coupled PDE; both the images and the curves on the frame/slices of interest are used for tracking. The technique can be applied to object tracking and sequential segmentation. The topology of the deforming curve can change without any special topology handling procedures added to the scheme. This permits, for example, the automatic tracking of scenes where, due to occlusions, the topology of the objects of interest changes from frame to frame. In addition, this work introduces the concept of projecting velocities to obtain systems of coupled PDEs for image analysis applications. We show examples for object tracking and segmentation of electronic microscopy     

Connection and coordination: the interplay between architecture and dynamics in evolved model pattern generators

We undertake a systematic study of the role of neural architecture in shaping the dynamics of evolved model pattern generators for a walking task. First, we consider the minimum number of connections necessary to achieve high performance on this task. Next, we identify architectural motifs associated with high fitness. We then examine how high-fitness architectures differ in their ability to evolve. Finally, we demonstrate the existence of distinct parameter subgroups in some architectures and show that these subgroups are characterized by differences in neuron excitabilities and connection signs.     

Making working memory work: a computational model of learning in the prefrontal cortex and basal ganglia

The prefrontal cortex has long been thought to subserve both working memory (the holding of information online for processing) and executive functions (deciding how to manipulate working memory and perform processing). Although many computational models of working memory have been developed, the mechanistic basis of executive function remains elusive, often amounting to a homunculus. This article presents an attempt to deconstruct this homunculus through powerful learning mechanisms that allow a computational model of the prefrontal cortex to control both itself and other brain areas in a strategic, task-appropriate manner. These learning mechanisms are based on subcortical structures in the midbrain, basal ganglia, and amygdala, which together form an actor-critic architecture. The critic system learns which prefrontal representations are task relevant and trains the actor, which in turn provides a dynamic gating mechanism for controlling working memory updating. Computationally, the learning mechanism is designed to simultaneously solve the temporal and structural credit assignment problems. The model's performance compares favorably with standard backpropagation-based temporal learning mechanisms on the challenging 1-2-AX working memory task and other benchmark working memory tasks.     

A new device for performing reference point indentation without a reference probe

Here we describe a novel, hand-held reference point indentation (RPI), instrument that is designed for clinical measurements of bone material properties in living patients. This instrument differs from previous RPI instruments in that it requires neither a reference probe nor removal of the periosteum that covers the bone, thus significantly simplifying its use in patient testing. After describing the instrument, we discuss five guidelines for optimal and reproducible results. These are: (1) the angle between the normal to the surface and the axis of the instrument should be less than 10°, (2) the compression of the main spring to trigger the device must be performed slowly (>1 s), (3) the probe tip should be sharper than 10 μm; however, a normalized parameter with a calibration phantom can correct for dull tips up to a 100 μm radius, (4) the ambient room temperature should be between 4?°C and 37 °C, and (5) the effective mass of the bone or material under test must exceed 1 kg, or if under 1 kg, the specimen should be securely anchored in a fixation device with sufficient mass (which is not a requirement of previous RPI instruments). Our experience is that a person can be trained with these guidelines in about 5 min and thereafter obtain accurate and reproducible results. The portability, ease of use, and minimal training make this instrument suitable to measure bone material properties in a clinical setting.     

Internet pornography exposure and risky sexual behavior among adult males in the United States

Sexually transmitted infections (STIs) continue to pose a threat to the public health in the United States. Many sexual behaviors increase an individual’s risk of STI contraction. Chief among these are having unprotected sex, having sex with multiple partners, and either paying for sex or having sex for pay. The present study used General Social Survey (GSS) data from 2000, 2002, and 2004 to explore the association between exposure to internet pornography and these STI risk behaviors among adult US males. After controlling for demographic and individual difference covariates, internet pornography consumption was positively associated with having sex with multiple partners, engaging in paid sex, and having had extramarital sex. Internet pornography consumption was unrelated to having unprotected sex. Subsequent GSSs have not asked participants about exposure to internet pornography. As the GSS is the only ongoing, full-probability, national survey assessing social beliefs and behaviors, the present report provides unique insight into the risky sexual behavior patterns of adult male internet pornography consumers in the United States.     

Exploring the impact of software requirements on system-wide goals: a method using satisfaction arguments and i* goal modelling

This paper describes the application of requirements engineering concepts to support the analysis of the impact of new software systems on system-wide goals. Requirements on a new or revised software component of a socio-technical system not only have implications on the goals of the subsystem itself, but they also impact upon the goals of the existing integrated system. In industries such as air traffic management and healthcare, impacts need to be identified and demonstrated in order to assess concerns such as risk, safety, and accuracy. A method called PiLGRIM was developed which integrates means-end relationships within goal modelling with knowledge associated with the application domain. The relationship between domain knowledge and requirements, as described in a satisfaction argument, adds traceability rationale to help determine the impacts of new requirements across a network of heterogeneous actors. We report procedures that human analysts follow to use the concepts of satisfaction arguments in a software tool for i* goal modelling. Results were demonstrated using models and arguments developed in two case studies, each featuring a distinct socio-technical system??a new controlled airspace infringement detection tool for NATS (the UK??s air navigation service provider), and a new version of the UK??s HIV/AIDS patient reporting system. Results provided evidence towards our claims that the conceptual integration of i* and satisfaction arguments is usable and useful to human analysts, and that the PiLGRIM impact analysis procedures and tool support are effective and scalable to model and analyse large and complex socio-technical systems.     

Working memory capacity and the top-down control of visual search: Exploring the boundaries of "executive attention".

The executive attention theory of working memory capacity (WMC) proposes that measures of WMC broadly predict higher order cognitive abilities because they tap important and general attention capabilities (R. W. Engle & M. J. Kane, 2004). Previous research demonstrated WMC-related differences in attention tasks that required restraint of habitual responses or constraint of conscious focus. To further specify the executive attention construct, the present experiments sought boundary conditions of the WMC-attention relation. Three experiments correlated individual differences in WMC, as measured by complex span tasks, and executive control of visual search. In feature-absence search, conjunction search, and spatial configuration search, WMC was unrelated to search slopes, although they were large and reliably measured. Even in a search task designed to require the volitional movement of attention (J. M. Wolfe, G. A. Alvarez, & T. S. Horowitz, 2000), WMC was irrelevant to performance. Thus, WMC is not associated with all demanding or controlled attention processes, which poses problems for some general theories of WMC. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Similarity-based interference during language comprehension: Evidence from eye tracking during reading.

The nature of working memory operation during complex sentence comprehension was studied by means of eye-tracking methodology. Readers had difficulty when the syntax of a sentence required them to hold 2 similar noun phrases (NPs) in working memory before syntactically and semantically integrating either of the NPs with a verb. In sentence structures that placed these NPs at the same linear distances from one another but allowed integration with a verb for 1 of the NPs, the comprehension difficulty was not seen. These results are interpreted as indicating that similarity-based interference occurs online during the comprehension of complex sentences and that the degree of memory accessibility conventionally associated with different types of NPs does not have a strong effect on sentence processing. (PsycINFO Database Record (c) 2010 APA, all rights reserved)