Expert judgement on the long term possibilities of conventional emission abatement technologies for passenger cars

Topics in Catalysis - This paper presents the results of a quantitatively substantiated “expert judgement” concerning the potential for further reduction of the exhaust emissions of...     

The effect of trans-isomers on the physical properties of hydrogenated oils

Data have been presented which indicate a positive relationship between thetrans-isomer content of a hydrogenated oil and the congeal point, Wiley melting-point, and solids index. It has also been shown that cottonseed oil and soybean oil undergo substantially the same type of reaction under identical hydrogenating conditions. This conclusion is based on the relationship oftrans-isomer formation to total reduction in unsaturation up to the point that equilibrium is reached and saturation of thetrans-isomers occurs. This equilibrium was noted at between 60–70 iodine value. The relationship oftrans-isomer formation to the total reduction in double bonds can be expressed as the hydrogenation index. This is a reliable indication of the type of reaction taking place up to the point where appreciable hydrogenation of thetrans-isomers occur.     

Triangulation in practice

Triangulation is the means by which an alternate perspective is used to validate, challenge or extend existing findings. It is frequently used when the field of study is difficult, demanding or contentious and presence research meets all of these criteria. We distinguish between the use of hard and soft triangulation—the former emphasising the challenging of findings, the latter being more confirmatory in character. Having reviewed a substantial number of presence papers, we conclude that strong triangulation is not widely used while soft triangulation is routinely employed. We demonstrate the usefulness of hard triangulation by contrasting an ontological analysis of in-ness with an empirical study of (computer) game playing. We conclude that presence research would be well served by the wider use of hard triangulation and for the reporting of anomalous and ill-fitting results.

Discriminating constant from variable angular velocities in structure from motion

We investigated accuracy in discriminating between constant and variable angular velocities for orthographic projections of three-dimensional rotating objects. The reported judgments of "constant" or "variable" angular velocity were only slightly influenced by the projected angular velocities, but they were greatly affected by the variations of the deformation, a first-order component of the optic flow. When viewing either a rotating ellipsoidal volume or a planar surface that accelerated and decelerated over the course of rotation, observers' tendencies to report a variable angular velocity were increased when the temporal phase of the acceleration pattern increased the range of variation of the median deformation; the tendencies were decreased when the same acceleration pattern was used to decrease the range of variation of the median deformation. These results provide evidence contrary to the hypothesis that the visual system performs a mathematically correct analysis of the optic flow.     

Shape optimization for tumor location

In non-invasive thermal diagnostics, accurate correlations between the thermal image at skin surface and interior human physiology are desired. In this work, an estimation methodology to determine unknown geometrical parameters of an embedded tumor is proposed. We define a functional that represents the mismatch between a measured experimental temperature profile, which may be obtained by infrared thermography on the skin surface, and the solution of an appropriate boundary problem. This functional is related to the geometrical parameters through the solution of the boundary problem, in such a way that finding the minimum of this functional form also means finding the unknown geometrical parameters of the embedded tumor. Sensitivity analysis techniques coupled with the adjoint method were considered to compute the shape derivative of the functional. Then, a nonmonotone spectral projected gradient method was implemented to solve the optimization problem of finding the optimal geometric parameters.     

Progression and Dissemination of Pulmonary Mycobacterium Avium Infection in a Susceptible Immunocompetent Mouse Model

Pulmonary infections caused by the group of nontuberculosis mycobacteria (NTM), Mycobacterium avium complex (MAC), are a growing public health concern with incidence and mortality steadily increasing globally. Granulomatous inflammation is the hallmark of MAC lung infection, yet reliable correlates of disease progression, susceptibility, and resolution are poorly defined. Unlike widely used inbred mouse strains, mice that carry the mutant allele at the genetic locus sst1 develop human-like pulmonary tuberculosis featuring well-organized caseating granulomas. We characterized pulmonary temporospatial outcomes of intranasal and left intrabronchial M. avium spp. hominissuis (M.av) induced pneumonia in B6.Sst1S mice, which carries the sst1 mutant allele. We utilized traditional semi-quantitative histomorphological evaluation, in combination with fluorescent multiplex immunohistochemistry (fmIHC), whole slide imaging, and quantitative digital image analysis. Followingintrabronchiolar infection with the laboratory M.av strain 101, the B6.Sst1S pulmonary lesions progressed 12–16 weeks post infection (wpi), with plateauing and/or resolving disease by 21 wpi. Caseating granulomas were not observed during the study. Disease progression from 12–16 wpi was associated with increased acid-fast bacilli, area of secondary granulomatous pneumonia lesions, and Arg1+ and double positive iNOS+/Arg1+ macrophages. Compared to B6 WT, at 16 wpi, B6.Sst1S lungs exhibited an increased area of acid-fast bacilli, larger secondary lesions with greater Arg1+ and double positive iNOS+/Arg1+ macrophages, and reduced T cell density. This morphomolecular analysis of histologic correlates of disease progression in B6.Sst1S could serve as a platform for assessment of medical countermeasures against NTM infection.