Algorithm for tissue ischemia estimation based on electrical impedance spectroscopy

The purpose of this paper is to present an algorithm developed for real-time estimation of skeletal muscle ischemia, based on parameters extracted from in vivo obtained electrical impedance spectra. A custom impedance spectrometer was used to acquire data sets: complex impedance spectra measured at 27 frequencies in the range of 100 Hz-1 MHz, and tissue pH. Twenty-nine in vivo animal studies on rabbit anterior tibialis muscle were performed to gather data on the behavior of tissue impedance during ischemia. An artificial neural network (ANN) was used to quantitatively describe the relationship between the parameters of complex tissue impedance spectra and tissue ischemia via pH. The ANN was trained on 1249, and tested on 946 ischemic tissue impedance data sets. A correlation of 94.5% and a standard deviation of 0.15 pH units was achieved between the ANN estimated pH and measured tissue pH values.     

可装入很小空间的简单电源

随着便携设备应用的普及,对负极性电压电源的需求逐渐增加.用一个正电压输入源来产生一个负电压电源这一做法,成本既高,又比较复杂,特别是当设计需要正电压和负电压两种输出时更是如此.图1示出了一个经济实惠的简单解决方案,它将一个电压逆变器和一个倍压器组合成一个电荷泵电路.该电路能利用一个5～6V的输入电压来产生一个-5V稳压输出电压和一个10V非稳压输出电压.它除了需要一个SOT-23封装的电荷泵集成电路之外,只需5只很小的表面安装陶瓷电容器和两只二极管.     

Statistical discriminant analysis of arrhythmias using intracardialelectrograms

The problem of classifying ventricular arrhythmias from intracardial electrograms is considered. Standard statistical discrimination procedures are applied using a simple parametric model for the shape of the pulse near its peak. This approach makes simultaneous use of the model parameters, has well known statistical properties, and involves computations that can be carried out efficiently. Preliminary analyses of real data sets, using both linear and quadratic discrimination functions, yield promising results     

Nonblocking multirate distribution networks

Results for nonblocking distribution networks are generalized for the multirate environment in which different user connections share a switch's internal data paths for arbitrary fractions of the total capacity. Conditions under which network proposed by Y.P. Ofman (1965), C.D. Thompson (1978), and N. Pippenger (1973) lead to multirate distribution networks are derived. The results include both rearrangement and wide-sense nonblocking networks. The complexity of the rearrangement multirate network exceeds that of the corresponding space-division network by a log log factor, while the complexity of the wide-sense nonblocking network is within a factor of two of the corresponding space-division network     

A Catalytic and Positively Thermosensitive Molecularly Imprinted Polymer

A catalytic and positively thermosensitive molecularly imprinted polymer is reported. This unique imprinted polymer was composed of 4‐nitrophenyl phosphate‐imprinted networks that exhibited a thermosensitive interpolymer interaction between poly(2‐trifluoromethylacrylic acid) (PTFMA) and poly(1‐vinylimidazole) (PVI), which contains catalytically active sites. At a relatively low temperature (such as 20 °C), this imprinted polymer did not demonstrate significant catalytic activity for the hydrolysis of 4‐nitrophenyl acetate due to the interpolymer complexation between PVI and PTFMA, which blocked access to the active sites of PVI and caused shrinking of the polymer. Conversely, at higher temperatures (such as 40 °C), this polymer showed significant catalytic activity resulting from the dissociation of the interpolymer complexes between PVI and PTFMA, which facilitated access to the active sites of PVI and inflated the polymer. Unlike previously reported poly(N‐isopropylacrylamide)‐based molecularly imprinted polymers, which demonstrated decreased molecular recognition and catalytic activity with increased temperatures, i.e., negatively thermosensitive molecular recognition and catalysis abilities, this imprinted polymer exploits the unique interpolymer interaction between PVI and PTFMA, enabling the reversed thermal responsiveness.     

A Zipper‐Like On/Off‐Switchable Molecularly Imprinted Polymer

A zipper‐like on/off‐switchable molecularly imprinted polymer is reported. This unique imprinted polymer was composed of template‐imprinted polymeric networks that incorporate zipper‐like interactions between poly(acrylamide) (PAAm) and poly(2‐acrylamide‐2‐methyl propanesulfonic acid) (PAMPS). This polymer showed marginal recognition ability towards the imprint species under low temperature conditions, due to the interpolymer interaction between PAAm and PAMPS, which inhibited access to the imprinted networks. In contrast, at relatively high temperatures (such as 40 °C), the polymer demonstrated significant molecular recognition ability towards the imprint species resulting from the dissociation of the interpolymer complexes of PAAm and PAMPS, which enabled access to the imprint networks. Unlike previously reported PNIPAm‐based imprinted polymers, which demonstrate alterable molecular recognition simply because of the thermosensitive hydrophilicity/hydrophobicity of PNIPAm, this polymer employed a zipper‐like supramolecular architecture between PAAm and PAMPS, thereby enabling switchable molecular recognition.     

High-power high-efficiency quasi-CW Sb-based mid-IR lasers using1.9-μm laser diode pumping

Power efficiency is a critical issue for mid-infrared (mid-IR) semiconductor lasers. Previously, the highest power and efficiency 4-μm laser was pumped with 0.98-μm laser diode. This letter used 1.9-μm diode pumping for better quantum defect ratio and heat flow geometry. A 3.7-μm InAsSb-AlAsSb laser yielded a pump-power-limited 1.25-W single-ended output in 1-ms-long pulse with 6.5% net optical-to-optical efficiency, in contrast with a 0.67-W thermally limited output and 2.7% efficiency with 0.98-μm diode pumping, at 70 K. The results are believed to represent the highest quasi-continuous-wave power from a single device, highest efficiency, and, scaled to the emitting aperture, highest power density for any 3-4-μm semiconductor laser for 1-ms pulse and ⩾70 K     

GaInAsSb-AlGaAsSb tapered lasers emitting at 2.05 μm with 0.6-Wdiffraction-limited power

Tapered lasers fabricated from a GaInAsSb-AlGaAsSb single-quantum-well structure are reported. The laser structure, grown by molecular beam epitaxy, has broad-stripe pulsed threshold current densities as low as 50 A/cm² at room temperature. Tapered lasers have exhibited diffraction-limited continuous-wave output power up to 600 mW     

Hydrogeochemistry and groundwater circulation in the Xi’an geothermal field, China

Geothermal waters from the Tertiary aquifers located at 1000–3000 m beneath Xi’an city, Shaanxi Province, China, show unique isotopic composition as compared to local groundwaters from shallower Quaternary aquifers. Positive oxygen shifts of as much as 8‰ VSMOW are observed, while the corresponding δ²H values remain essentially constant at about −80‰ VSMOW, which is significantly different from those of waters in the Quaternary aquifers with a mean δ²H value of −60‰ VSMOW. The strong ¹⁸O shift is a result of isotope exchange between geothermal water and carbonate minerals such as calcite over a residence time of several thousand years up to 30,000 years, based on ¹⁴C dating. A comparison of the isotopic composition of geothermal waters with neighbouring groundwater units on both sides of the Guanzhong Basin indicates that the geothermal reservoirs are recharged by rain that falls on the northern slope of the Qinling Mountains, south of the Xi’an geothermal field, but not from the North Mountains to the north of the field. Based on chemical geothermometers the highest temperature estimated for the Tertiary aquifers of the Xi’an area is around 130 °C.