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51.
    
The International Organization for Standardization evacuation alarm (ISO 8201: 2017) is ineffective in initiating evacuation, particularly when people are engaged in pre-evacuation activities, and it is not easy to conduct experiments for evaluating evacuation behavior due to ethical and cost issues. A virtual building emergency where alarms went off while participants were performing activities was created to study the effect of redundancy on evacuation effectiveness. Three alarms were studied: (i) a regular nonverbal ISO alarm, (ii) a speech-inserted ISO alarm, and (iii) a technology-based ISO alarm concept (sound, visual, and haptic information). Evacuation behavior, perceived urgency, and delay time were measured. Results confirmed the effect of redundancy on measurements, and participants complied better with the speech-inserted and technology-based alarms, but there were no differences in evacuation effectiveness between them. Participants perceived higher urgency from the technology-based solution, which can be more adaptive in complicated environments where background noise and language/education barriers are problems. Otherwise, the speech-inserted alarm is more cost-effective.  相似文献   
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Recently, much attention has been paid to the COVID-19 pandemic. Yet bacterial resistance to antibiotics remains a serious and unresolved public health problem that kills hundreds of thousands of people annually, being an insidious and silent pandemic. To contain the spreading of the SARS-CoV-2 virus, populations confined and tightened hygiene measures. We performed this study with computer simulations and by using mobility data of mobile phones from Google in the region of Lisbon, Portugal, comprising 3.7 million people during two different lockdown periods, scenarios of 40 and 60% mobility reduction. In the simulations, we assumed that the network of physical contact between people is that of a small world and computed the antibiotic resistance in human microbiomes after 180 days in the simulation. Our simulations show that reducing human contacts drives a reduction in the diversity of antibiotic resistance genes in human microbiomes. Kruskal–Wallis and Dunn’s pairwise tests show very strong evidence (p < 0.000, adjusted using the Bonferroni correction) of a difference between the four confinement regimes. The proportion of variability in the ranked dependent variable accounted for by the confinement variable was η2 = 0.148, indicating a large effect of confinement on the diversity of antibiotic resistance. We have shown that confinement and hygienic measures, in addition to reducing the spread of pathogenic bacteria in a human network, also reduce resistance and the need to use antibiotics.  相似文献   
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研究了Fe-15Nb和Fe-30Nb(Wt%)合金在600~800℃低氧压气氛中的氧化行为,实验所用的氧压处于煤的气化气氛下的氧分压范围。氧化后合金仅发生了Nb的内氧化,生成Nb2与Nb2O5,有些情况下还生成FeNb2O6。在600℃时氧化速度很低,但在700~800℃时则颇高。这些合金内氧化的重要特征之一,是其内氧化物的分布几乎完全与合金中的高含Nb相一致。此外,合金氧化后均不出现外氧化层。这些可能都是由于Nb在Fe中溶解度很低且合金呈两相组织所致。  相似文献   
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The constant increase in the wind power production leads to the need of higher wind towers, which brings up some questions regarding the effectiveness of tubular towers and respective foundations. This work focuses on the comparative structural design, life cycle behaviour and costs of onshore concrete shallow foundations for tubular wind towers (WT) when steel micropiles are used to improve resistance of the soil–structure interface (hybrid foundation). Typical wind loading for Turbine Class II and moderate seismicity (.25 g peak ground acceleration) is used to design and analyse 18 WT foundation case studies. This allows the comparison between shallow and hybrid foundations designed for three different hub heights and respective turbine rated power (80 m/2 MW, 100 m/3.6 MW and 150 m/5 MW) and for three different tubular tower solutions (steel, concrete and hybrid steel–concrete). The possible benefits of the solution using steel grouted micropiles are discussed in terms of potential environmental and economic impacts using life cycle analysis. The use of micropiles reveals to be an interesting solution to improve common shallow WT foundations since it allows the reduction of the dimensions of the foundation leading to significant environmental and cost benefits.  相似文献   
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The aim of this study was to assess the influence of detraining and training on the autonomic control of heart rate (HR), using time and frequency (spectral analysis) domain components of heart rate variability. Sixteen professional football players (26.7 +/- 3.8 years; 74.9 +/- 4.1 kg; 177 +/- 6.3 cm) were analysed at the end of a 1 month holiday (detraining) and after a 6 week training period (training). HR was recorded over 15 minutes with Holter equipment. The athletes rested in a supine position, in a quiet place and all test were performed between 8 and 10 AM. The subjects were requested to refrain from meals or caffeine for 12 hours before testing. In spite of the high intensity of the training period, there was no significant change in results from detraining condition to training condition. These results can have two possible explanations: (i) the high level of cardiovascular capacity in the detraining trial originated by the recreative physical activity that the players underwent during their holidays, and/or (ii) the training period was not long enough to promote any relevant effect on the autonomic control of HR.  相似文献   
57.
Data Mining and Knowledge Discovery - Through the quantification of physical activity energy expenditure (PAEE), health care monitoring has the potential to stimulate vital and healthy ageing,...  相似文献   
58.
Polyphenolic compounds present in wine have a high antioxidant capacity providing a protective effect on human health. There is a worldwide agreement on this assertion. However, there is no agreement on the method of assessing the antioxidant capacity of wines. The purpose of this study was to emphasize the ability of the laccase-based biosensor developed by our group to evaluate the antioxidant capacity of several types of wine in relation to their polyphenolic content. The values of total antioxidant activity of the investigated wine samples were well correlated with the corresponding bioelectrochemical polyphenol-estimated values, the correlation coefficient obtained being r = 0.9795 (p < 0.05). The linear relationship between total antioxidant activity and bioelectrochemical polyphenol index determined by laccase-based biosensor enabled the calculation of the TEAC (Trolox Equivalent Antioxidant Capacity) of a wine from its bioelectrochemical polyphenol index.  相似文献   
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This study considers the relationship between the approach to urban planning in Portugal up to the eighteenth century, and the effective process of urbanisation, from both a theoretical and practical perspective. Portuguese urban layout does not develop as a set of random shapes but rather arises from structured thinking by “urban makers” who are firmly grounded in the subject of geometry. Being able to measure the universe and codify it in drawings was one of the major scientific accomplishments of the age of Portuguese discoveries in the sixteenth century and the acquisition of such knowledge demanded a unique ability for abstraction which could not have simply emerged out of nothing. Portugal’s investment in the training of skilled professionals is made evident in treatises, manuals, dissertations, and cartography and iconography works. The interpretation of the ideas of Order and Space in urban design evolved through history in parallel with the evolution of philosophical and scientific thought. In fact, urban space is associated the search of the laws of the nature and the intelligibility of the cosmos.  相似文献   
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