Design of observers with delayed sampled data

A design procedure for continuous-time full-order observers driven by delayed sampled data is presented. The observer feedback matrix is assumed to be of nonunity rank. In a previous paper the use of a unity rank observer feedback matrix was described. A numerical example is given to illustrate the advantage of this design procedure.     

A UMOS power field effect transistor

A power MOST switch fabricated using a U-shaped groove anisotropically etched in silicon is described. The structure provides a short channel while maintaining a reasonable breakdown voltage. Devices with a channel length of 2–3 μm and an active area of 0.23 mm² exhibit breakdown voltages ranging from 35 to 45V with a current handling capability of 1A and a switching time of less than 5 nsec.     

V-groove power junction field-effect transistor for v.h.f. applications

A new high-power, high-frequency junction field-effect transistor with a nonplanar V-shaped channel fabricated by preferential etching of ?100? silicon is described. The structure of this transistor is very simple, requires only three photolithographic masking steps and results in a very high packing density. A device having an effective channel length of 2 ?m was fabricated. This transistor exhibits a low-frequency transconductance of 9.6 mS/mm, a cutoff frequency of 0.9 GHz and an output power density of 25 W/mm2 of chip area.     

V groove m.o.s. transistor technology

An m.o.s. transistor structure in which the channel is defined by preferential etching of the silicon is described. The fabrication technology involves either a 3- or 4-mask process, and results in very-short-channel devices, using noncritical alignment tolerances. Experimental results obtained on the fabricated devices are presented, and possible uses of the technology are described.     

On the Rheology of Polyoxyethylene Sorbitol Lanolin Derivatives

Three members of polyoxyethylene sorbitol lanolin derivatives were investigated for their rheological characteristics. The investigation included the study of phenomena of consistency, breakdown and regeneration of the gel structure.     

On the Influence of Liquid Derivatives of Lanolin on the Rheology of Hydrocarbon Ointment Bases

Three members of liquid derivatives of lanolin representing three basically different types of these derivatives were studied for their rheological characteristics. The rheological investigation was performed through the determination of flow curve, structural viscosity, yield value, plastic viscosity, coefficients M and B of thixotropic breakdown and quotient R of structural recovery.     

Realization of Fully Controllable Negative Inductance with Single Operational Transresistance Amplifier

A grounded negative inductance emulator is proposed with full independent control on both the inductance value and the condition. It uses a single operational transresistance amplifier (OTRA), a capacitor, and five resistors, two of which are for independent control. Experimental results, which confirm the theoretical analysis, are presented.     

Crystallization and Ability of Hydroxyapatite Formation in Some Trivalent Oxides Containing Na-Ca-Silicate Glass-Ceramics

The formation of glass-ceramics based on Na₂O–CaO-silicates containing P₂O₅ with minor additives of some trivalent oxides (e.g. La, In, Ga, and Al), has been investigated. Different crystalline phases including sodium-orthosilicate containing lanthanum, or aluminum were formed together with Na₂Ca₂Si₃O₉, NaInSi₂O₆, and Na₃Ga₂Si₃O₁₀. The nature and mechanism of HA formed in the glass-ceramics are considered. In general, the presence of trivalent oxides in the glass-ceramics progressively reduced the ability to form a calcium phosphate layer on the surfaces of the materials. The addition of In₂O₃ decreased the crystallization of the hydroxyapatite layer. However, in the presence of either Ga₂O₃ or Al₂O₃ only the amorphous calcium phosphate layer was formed after the immersion of the crystallized specimens in the SBF solution.     

PRKAR1B-AS2 Long Noncoding RNA Promotes Tumorigenesis,Survival, and Chemoresistance via the PI3K/AKT/mTOR Pathway

Many long noncoding RNAs have been implicated in tumorigenesis and chemoresistance; however, the underlying mechanisms are not well understood. We investigated the role of PRKAR1B-AS2 long noncoding RNA in ovarian cancer (OC) and chemoresistance and identified potential downstream molecular circuitry underlying its action. Analysis of The Cancer Genome Atlas OC dataset, in vitro experiments, proteomic analysis, and a xenograft OC mouse model were implemented. Our findings indicated that overexpression of PRKAR1B-AS2 is negatively correlated with overall survival in OC patients. Furthermore, PRKAR1B-AS2 knockdown-attenuated proliferation, migration, and invasion of OC cells and ameliorated cisplatin and alpelisib resistance in vitro. In proteomic analysis, silencing PRKAR1B-AS2 markedly inhibited protein expression of PI3K-110α and abrogated the phosphorylation of PDK1, AKT, and mTOR, with no significant effect on PTEN. The RNA immunoprecipitation detected a physical interaction between PRKAR1B-AS2 and PI3K-110α. Moreover, PRKAR1B-AS2 knockdown by systemic administration of 1,2-dioleoyl-sn-glycero-3-phosphatidylcholine nanoparticles loaded with PRKAR1B-AS2–specific small interfering RNA enhanced cisplatin sensitivity in a xenograft OC mouse model. In conclusion, PRKAR1B-AS2 promotes tumor growth and confers chemoresistance by modulating the PI3K/AKT/mTOR pathway. Thus, targeting PRKAR1B-AS2 may represent a novel therapeutic approach for the treatment of OC patients.     

Antibacterial and anti-adhesive efficiency of Pediococcus acidilactici against foodborne biofilm producer Bacillus cereus attached on different food processing surfaces

Food Science and Biotechnology - This study aimed to assess the biofilm formation by Bacillus cereus on two novel surfaces namely: aluminum and cold steel in comparison study with stainless steel...