Prediction of Bending Fatigue Life of Cracked Out-of-Plane Gusset Joint Repaired by CFRP Plates

Carbon fiber reinforced polymer (CFRP), plates bonding repair method is one of the simple repair methods for cracked steel structures. In this study, the influence of width of CFRP plates on bending fatigue life of out-of-plane gusset joint strengthened with CFRP plates was investigated from the experimental and numerical point of view. In the bending fatigue test of cracked out-of-plane gusset joint strengthened with CFRP plates, the effect of width of CFRP plates on crack growth life was clarified experimentally. Namely, it was revealed that the crack growth life becomes larger with increasing the width of CFRP plates. In the numerical approach, the stress intensity factor (SIF) at the surface point of a semi-elliptical surface crack was estimated based on the linear fracture mechanics. Furthermore, the extended fatigue life of cracked out-of-plane gusset joint strengthened with CFRP plates was evaluated by using the estimated SIF at the surface point and the empirical formula of the aspect ratio of semi-elliptical crack. As the results of numerical analysis, the estimated fatigue life of the specimen strengthened with CFRP plates showed the good agreement with the test results.     

A human-machine cooperative system for generating sign language animation using thermal image

We propose a new approach aimed at sign language animation by skin region detection on an infrared image. To generate several kinds of animations expressing personality and/or emotion appropriately, conventional systems require many manual operations. However, a promising way to realize a lower workload is to manually refine an animation made automatically with a dynamic image of real motion. In the proposed method, a 3D CG model corresponding to a characteristic posture in sign language is made automatically by pattern recognition on a thermal image, and then a person’s hand in the CG model is set. The hand part is made manually beforehand. If necessary, the model can be replaced manually by a more appropriate model corresponding to training key frames and/or the model can be refined manually. In our experiments, a person experienced in using sign language recognized the Japanese sign language of 71 words expressed as animation with 88.3% accuracy, and three persons experienced in using sign language also recognized the sign language animation representing three emotions (neutral, happy and angry) with 88.9% accuracy. This work was presented in part at the 13th International Symposium on Artificial Life and Robotics, Oita, Japan, January 31–February 2, 2008     

基于眼前节相干光断层扫描成像的核性白内障分类算法

白内障是导致视觉损害和致盲的主要眼病,眼前节光学相干断层成像技术(Anterior Segment Optical Coherence Tomography,AS-OCT)具有非接触、高分辨率、检查快速、客观定量化测量等特点,在临床上已经被广泛应用于眼病的诊断.目前缺乏基于眼前节OCT图像的核性白内障分类研究工作,为此...     

Cardiovascular Characteristics of Zucker Fatty Diabetes Mellitus Rats,an Animal Model for Obesity and Type 2 Diabetes

Zucker fatty diabetes mellitus (ZFDM) rats harboring the missense mutation (fa) in a leptin receptor gene have been recently established as a novel animal model of obesity and type 2 diabetes (T2D). Here, we explored changes in cardiovascular dynamics including blood pressure and heart rate (HR) associated with the progression of obesity and T2D, as well as pathological changes in adipose tissue and kidney. There was no significant difference in systolic blood pressure (SBP) in ZFDM-Lepr^fa/fa (Homo) compared with ZFDM-Lepr^fa/+ (Hetero) rats, while HR and plasma adrenaline in Homo were significantly lower than Hetero. The mRNA expression of monocyte chemotactic protein-1 in perirenal white adipose tissue (WAT) from Homo was significantly higher than Hetero. Interscapular brown adipose tissue (BAT) in Homo was degenerated and whitened. The plasma blood urea nitrogen in Homo was significantly higher than Hetero. In summary, we demonstrated for the first time that HR and plasma adrenaline concentration but not SBP in Homo decrease with obesity and T2D. In addition, inflammation occurs in WAT from Homo, while whitening occurs in BAT. Further, renal function is impaired in Homo. In the future, ZFDM rats will be useful for investigating metabolic changes associated with the progression of obesity and T2D.     

The concept of task versus person orientation in nursing.

To clarify the concept of task versus person orientation in nursing, a factor analysis of 24 personality-and nursing-attitude variables was performed on 160 nurses from long- and short-term treatment settings in psychiatry and general medicine. 3 factors, Leadership Skills, Hostile-Self-Seeking, and Dependent-Exploited sampled behaviors in the interpersonal sphere and particularly traits related to leadership capability. The 4th factor, Impersonal-Orderly, contained many characteristics of the "Authoritarian Personality." An emphasis on the skilled technical aspects of nursing was one of the elements in this factor. In general, the derived factor scores effectively differentiated nurses from the treatment settings in this study. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

VLCC液舱晃荡仿真模型

分别采用3D模型和2D模型对VLCC液舱进行晃荡仿真,通过对两个模型的流体流动情况和对应位置压力的比较,得出短期搜索及长期分析中采用2D模型方案进行VLCC液舱晃荡仿真分析是可行的结论. 讨论两种模型的计算效率,认为2D模型方案可以大大提高仿真效率,具有工程实用性.     

Initial validation of a computer-administered Addiction Severity Index: The ASI–MV.

The Addiction Severity Index—Multimedia Version (ASI–MV) is a CD-ROM-based simulation of the interview-administered Addiction Severity Index (ASI). Clients in treatment (N ?=?202) self-administered the ASI–MV to examine the test–retest reliability, criterion validity, and convergent–discriminant validity of the ASI–MV. Excellent test–retest reliability was observed for composite scores and severity ratings. Criterion validity, tested against the interviewer-administered ASI, was good for the composite scores. For severity ratings, variable agreement was observed between the ASI–MV and each interviewer, suggesting poor interrater reliability among interviewers. This conclusion was bolstered by a finding of superior convergent–discriminant validity for both composite scores and severity ratings compared to the standard ASI. The ASI–MV is a viable alternative to the expensive and potentially unreliable interviewer-administered version. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Extending fatigue life of out-of-plane gusset joint by bonding CFRP plates under bending moment

International Journal of Steel Structures - Carbon fiber reinforced plastic, CFRP, plates bonding method is one of the new repair methods for fatigue cracks. In this method, propagation of fatigue...     

Metabolism of (+)-terpinen-4-ol by cytochrome P450 enzymes in human liver microsomes

We examined the in vitro metabolism of (+)-terpinen-4-ol by human liver microsomes and recombinant enzymes. The biotransformation of (+)-terpinen-4-ol was investigated by gas chromatography-mass spectrometry (GC-MS). (+)-Terpinen-4-ol was found to be oxidized to (+)-(1R,2S,4S)-1,2-epoxy-p-menthan-4-ol, (+)-(1S,2R,4S)-1,2-epoxy-p-menthan-4-ol, and (4S)-p-menth-1-en-4,8-diol by human liver microsomal P450 enzymes. The identities of (+)-terpinen-4-ol metabolites were determined through the relative abundance of mass fragments and retention times on GC-MS. Of 11 recombinant human P450 enzymes tested, CYP1A2, CYP2A6, and CYP3A4 were found to catalyze the oxidation of (+)-terpinen-4-ol. Based on several lines of evidence, CYP2A6 and CYP3A4 were determined to be major enzymes involved in the oxidation of (+)-terpinen-4-ol by human liver microsomes. First, of the 11 recombinant human P450 enzymes tested, CYP1A2, CYP2A6 and CYP3A4 catalyzed oxidation of (+)-terpinen-4-ol. Second, oxidation of (+)-terpinen-4-ol was inhibited by (+)-menthofuran and ketoconazole, inhibitors known to be specific for these enzymes. Finally, there was a good correlation between CYP2A6 and CYP3A4 activities and (+)-terpinen-4-ol oxidation activities in the 10 human liver microsomes.