Antimicrobial materials based on poly(ethylene-co-vinyl alcohol) and silver acetate produced by reactive extrusion

The use of silver as an antimicrobial agent has exhibited great interest in recent years. In this research, poly(ethylene-co-vinyl alcohol) (EVOH)–silver acetate-based antimicrobial materials were prepared at high temperature by reactive extrusion. Silver acetates were used without pretreatment. The thermal reaction of silver acetates in the material and their effect on the thermal and mechanical properties of the polymer were investigated as a function of their concentration. The dispersed silver acetate salts within the EVOH matrix have displayed a significant thermal reaction. This reaction of metallic salts was partial when the extrusion temperature was fixed at 190 °C and completed at 230 °C. The antimicrobial agents also had significant effects on the properties of the matrix. Reductions of glass temperature and storage modulus were observed by the analyses. All the variations were dependent on both the concentration of silver acetate and the extrusion parameters. The antimicrobial activity was studied and demonstrated a promising potential to create an antimicrobial material in a one-step solvent free extrusion method. © 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019 , 136, 47799.     

Virus-Based Nanoreactors with GALT Activity for Classic Galactosemia Therapy

Enzymatic nanoreactors were obtained by galactose-1-phosphate uridylyl-transferase (GALT) encapsulation into plant virus capsids by a molecular self-assembly strategy. The aim of this work was to produce virus-like nanoparticles containing GALT for an enzyme-replacement therapy for classic galactosemia. The encapsulation efficiency and the catalytic constants of bio-nanoreactors were determined by using different GALT and virus coat protein ratios. The substrate affinity of nanoreactors was slightly lower than that of the free enzyme; the activity rate was 16 % of the GALT free enzyme. The enzymatic nanoreactors without functionalization were internalized into different cell lines including fibroblast and kidney cells, but especially into hepatocytes. The enzymatic nanoreactors are an innovative enzyme preparation with potential use for the treatment of classic galactosemia.     

Performance Evaluation of Two High‐Shear Impellers in an Unbaffled Stirred Tank

High‐shear impellers (HSIs) are mixers used in industrial stirred tanks to incorporate powders into liquids and break down particle agglomerates. A detailed numerical study of two commercial ring‐style HSIs of laboratory scale was carried out and their performance was compared with the Rushton turbine (RT). It was found that power and pumping numbers or their ratio cannot be simply connected for properly selecting an impeller in applications where highly localized viscous dissipation is desirable. The ratio of the average viscous dissipation in the impeller swept volume to the mean in the entire volume at two constant values of power input turned out to be lower for HSIs compared to that evaluated for RT. However, at higher power input, the dimensionless average viscous dissipation in the blade swept volume was found to be similar for the HSI of two rings and the RT, corroborating the high local viscous dissipation of this HSI when operated at higher speeds.     

Describing natural colors with Munsell and NCS color systems

The Munsell Color System and the Natural Color System are widely used but they have some limitations due to the manufacturing process and sampling choices. To estimate quantitatively these limitations we compared the colors of natural scenes with the colors represented by these systems under a wide range of illuminants. Spectral data from the two systems and from natural scenes were used in the analysis. It was found that a considerable portion of natural colors are not accounted by these systems, mainly colors with low lightness levels. Under D65 the Munsell Color System color volume corresponds to 72% of the Natural Color System color volume which in turn represents only 53% of the natural scenes color volume. If individual colors are considered, less than half are contained within these systems. To obtain a complete match to the natural colors contained by the color systems thresholds of 7 and 5 CIELAB units would be required for Munsell Color System and Natural Color System, respectively. Variations with the illuminant are generally modest showing that both system work similarly across different illuminations. Although these Color Systems have limitations in describing low lightness colors they perform quite well for medium to high levels of lightness.     

Implementation of periodic boundary conditions for loading of mechanical metamaterials and other complex geometric microstructures using finite element analysis

The implementation of periodic boundary conditions (PBCs) is one of the most important and difficult steps in the computational analysis of structures and materials. This is especially true in cases such as mechanical metamaterials which typically possess intricate geometries and designs which makes finding and implementing the correct PBCs a difficult challenge. In this work, we analyze one of the most common PBCs implementation technique, as well as implement and validate an alternative generic method which is suitable to simulate any possible 2D microstructural geometry with a quadrilateral unit cell regardless of symmetry and mode of deformation. A detailed schematic of how both these methods can be employed to study 3D systems is also presented.

     

Managing Water to Minimize Risk in Tailings Storage Facility Design,Construction, and Operation

Mine Water and the Environment - Reducing the amount of water in a milled tailings storage facility (TSF) is the primary way to reduce the risk of a catastrophic failure. In addition, a significant...     

DC servomechanism parameter identification: a Closed Loop Input Error approach

This paper presents a Closed Loop Input Error (CLIE) approach for on-line parametric estimation of a continuous-time model of a DC servomechanism functioning in closed loop. A standard Proportional Derivative (PD) position controller stabilizes the loop without requiring knowledge on the servomechanism parameters. The analysis of the identification algorithm takes into account the control law employed for closing the loop. The model contains four parameters that depend on the servo inertia, viscous, and Coulomb friction as well as on a constant disturbance. Lyapunov stability theory permits assessing boundedness of the signals associated to the identification algorithm. Experiments on a laboratory prototype allows evaluating the performance of the approach.