Sorption and Desorption of Water Vapour on Starch

Adsorption-desorption isotherms for water vapour on starch have been obtained by the use of quartz fibre spring technique. The specific surface area of starch has been calculated by the BET and HJ methods and the values are in close agreement with each other.     

A space-time channel estimator and single-user receiver for code-reuse DS-CDMA systems

A blind asynchronous single-user code-reuse direct sequence code division multiple access (CDMA) array receiver is proposed for the uplink. By assigning each short PN-code more than once, code reuse allows the number of active users to be increased beyond the spreading gain. The proposed receiver is based on a blind single-code multipath joint space-time channel estimation technique that utilizes the concept of the spatio-temporal array manifold, in conjunction with a novel preprocessor, to deal with the multipath problem. From the estimated space-time channel parameters of a particular active code, the subset of parameters of a specific co-code user is then identified, and a single-user receiving weight vector is finally formed. The proposed approach is a subspace type method, and therefore, it is "near-far" resistant. Furthermore, in contrast to existing receivers such as the space-time decorrelating detector, the proposed receiver weight vector is tolerant to partial channel estimation errors and the incomplete estimation of channel parameters. The theoretical framework is supported by computer simulation studies.     

Circular expressions: elimination of static environments

Consider the connection between denotational semantics for a language with goto statements and flow diagrams for programs in such a language. The main point of interest is that the denotational semantics uses a recursively defined environment to give the meaning of labels, while a flow diagram merely has a jump to the appropriate program point. A simple reduction called “indirection elimination” strips away the environment from the denotational semantics and extracts an expression with cycles that is very close to the flow diagram of a program. The same idea applies to associating bodies with recursive procedures, or to any construct whose semantics is not wedded to the syntax. In addition to being a useful data structure and conceptual device, expressions with cycles are well defined mathematical objects—their semantics can be given by unfolding them into infinite structures that have been well studied. The practicality of the elimination of environments has been tested by constructing a trial implementation, which serves as the front end of a semantics directed compiler generator. The implementation takes a denotational semantics of a language and constructs a “black box” that maps programs in the language into an intermediate representation. The intermediate representation is a circular expression.     

Data Fusion of Fixed Detector and Probe Vehicle Data for Incident Detection

An important feature of many advanced traveler information systems (ATIS) is real-time information about incidents on the street network. This paper describes a system for automatically detecting incidents for such an ATIS developed using artificial neural networks and statistical prediction methods. The system monitors traffic conditions using two types of data: inductive loop detectors (ILDs) and vehicle probes. For both neural network and statistical methods, incident detection is accomplished using two approaches: by processing traffic input data directly and by processing the output of specialized algorithms that detect incidents using information from each data source. Analysis data generated from a simulation of a typical suburban signalized major arterial street are used. Different model configurations are examined and tested to identify the input variables and methods that are the best predictors of incident occurrence. The neural network approaches consistently perform at least as well as the discriminant analysis models, especially when results are adjusted to avoid false alarms.     

Characterization of reactive graphene oxide synthesized from ball – milled graphite: its enhanced reinforcing effects on cement nanocomposites

In this study, commercial graphite powder (GP) of particle size 100 micron was subjected to high energy ball-milling (HEBM) to produce ball-milled graphite powder (BMGP) of particle size 780 nm. Both GP and BMGP were converted to respective graphene oxides (GOs) (labeled as GO1 and GO2) using Hummer’s method, which were then characterized using techniques such as scanning electron microscopy (SEM), transmission electron microscopy (TEM), and X- ray diffraction (XRD). GO1 and GO2 were then investigated for their effects on compressive strength of cement mortar matrix at different curing times of 7, 14, and 28 days. Effect of variation of concentration (ranging between 0.125 and 1.00 wt% of cement) of GO1 and GO2 on the strength of matrix was examined. Microstructures of GO1-cement mortar nanocomposite and GO2-cement mortar nanocomposite were studied after 28 days of curing using SEM. Obtained results show that addition of 1.00 wt% GO1 and GO2 showed best performance by increasing the strength to 63 and 78%, respectively, in comparison to the unreinforced control sample. Improved performance of GO2 was attributed to more number of reactive sites of GO nanosheets induced by ball-milling treatment of graphite precursor.     

Galectin‐3‐Binding Glycomimetics that Strongly Reduce Bleomycin‐Induced Lung Fibrosis and Modulate Intracellular Glycan Recognition

Discovery of glycan‐competitive galectin‐3‐binding compounds that attenuate lung fibrosis in a murine model and that block intracellular galectin‐3 accumulation at damaged vesicles, hence revealing galectin‐3–glycan interactions involved in fibrosis progression and in intracellular galectin‐3 activities, is reported. 3,3′‐Bis‐(4‐aryltriazol‐1‐yl)thiodigalactosides were synthesized and evaluated as antagonists of galectin‐1, ‐2, ‐3, and ‐4 N‐terminal, ‐4 C‐terminal, ‐7 and ‐8 N‐terminal, ‐9 N‐terminal, and ‐9 C‐terminal domains. Compounds displaying low‐nanomolar affinities for galectins‐1 and ‐3 were identified in a competitive fluorescence anisotropy assay. X‐ray structural analysis of selected compounds in complex with galectin‐3, together with galectin‐3 mutant binding experiments, revealed that both the aryltriazolyl moieties and fluoro substituents on the compounds are involved in key interactions responsible for exceptional affinities towards galectin‐3. The most potent galectin‐3 antagonist was demonstrated to act in an assay monitoring galectin‐3 accumulation upon amitriptyline‐induced vesicle damage, visualizing a biochemically/medically relevant intracellular lectin–carbohydrate binding event and that it can be blocked by a small molecule. The same antagonist administered intratracheally attenuated bleomycin‐induced pulmonary fibrosis in a mouse model with a dose/response profile comparing favorably with that of oral administration of the marketed antifibrotic compound pirfenidone.     

Improvement in greenhouse solar drying using inclined north wall reflection

A conventional greenhouse solar dryer of 6 m² × 4 m² floor area (east-west orientation) was improved for faster drying using inclined north wall reflection (INWR) under natural as well as forced convection mode. To increase the solar radiation availability onto the product (to be dried) during extreme summer months, a temporary inclined wall covered with aluminized reflector sheet (of 50 μm thickness and reflectance 0.93) was raised inside the greenhouse just in front of the vertical transparent north wall. By doing so, product fully received the reflected beam radiation (which otherwise leaves through the north wall) in addition to the direct total solar radiation available on the horizontal surface during different hours of drying. The increment in total solar radiation input enhanced the drying rate of the product by increasing the inside air and crop temperature of the dryer. Inclination angle of the reflective north wall with vertical (β) was optimized for various selective widths of the tray W (1.5, 2, 2.5 and 3 m) and for different realistic heights of existing vertical north wall (h) at 25°N, 30°N and 35°N latitudes (hot climatic zones). Experimental performance of the improved dryer was tested during the month of May 2008 at Ludhiana (30.56°N) climatic conditions, India by drying bitter gourd (Momordica charantia Linn) slices. Results showed that by using INWR under natural convection mode of drying, greenhouse air and crop temperature increased by 1-6.7 °C and 1-4 °C, respectively, during different drying hours as compared to, when INWR was not used and saved 13.13% of the total drying time. By using INWR under forced convection mode of drying, greenhouse air and crop temperature increased by 1-4.5 °C and 1-3 °C, respectively, during different drying hours as compared to, when INWR was not used and saved 16.67% of the total drying time.     

Using temporal correlation for fault localization in dynamically changing networks

A mobile ad hoc network creates a dynamic environment where node mobility can cause periodic changes in routes. Most existing fault localization algorithms assume availability of a complete and/or deterministic dependency model. Such assumptions cannot be made in the dynamically changing networks. This paper is aimed at developing a fault diagnosis architecture and algorithm to address the issue of dynamically changing dependencies in networks. We propose an architecture to capture the changes in dependencies and introduce a temporal correlation algorithm to perform fault diagnosis with the dynamically changing dependency information. We present an experimental evaluation of our work through simulation results using Qualnet. Copyright © 2007 John Wiley & Sons, Ltd.     

Clinical Advances in Molecular Biomarkers for Cancer Diagnosis and Therapy

Cancer diagnosis is currently undergoing a paradigm shift with the incorporation of molecular biomarkers as part of routine diagnostic panel. The molecular alteration ranges from those involving the DNA, RNA, microRNAs (miRNAs) and proteins. The miRNAs are recently discovered small non-coding endogenous single-stranded RNAs that critically regulates the development, invasion and metastasis of cancers. They are altered in cancers and have the potential to serve as diagnostic markers for cancer. Moreover, deregulating their activity offers novel cancer therapeutic approaches. The availability of high throughput techniques for the identification of altered cellular molecules allowed their use in cancer diagnosis. Their application to a variety of body specimens from blood to tissues has been helpful for appreciating their use in the clinical context. The development of innovative antibodies for immunohistochemical detection of proteins also assists in diagnosis and risk stratification. Overall, the novel cancer diagnostic tools have extended their application as prognostic risk factors and can be used as targets for personalized medicine.