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31.
本文章旨在介绍配合使用NetBeans Profiler v5.0或Profiler Milestone 8的内容。如果您使用的是Milestone 5或Mile- store 6,请使用此版本。 相似文献
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Raquel Martín-Venegas M.Teresa Brufau Ana Maria Guerrero-Zamora Yves Mercier Pierre-André Geraert Ruth Ferrer 《Food chemistry》2013
dl-2-hydroxy-(4-methylthio)butanoic acid (HMTBA) is a source of dietary methionine (Met) that is widely used in poultry nutrition. We have previously shown that HMTBA is preferentially diverted to the transsulfuration pathway, which gives antioxidant metabolites such as taurine and glutathione. Therefore, here we hypothesize that this Met source can protect epithelial barrier function in an in vitro model of intestinal inflammation of Caco-2 cells. The results show that HMTBA prevents the increase in paracellular permeability induced by H2O2 or tumour necrosis factor-α. This effect can be attributed to the increased production of taurine and reduced glutathione. Similar results were obtained for dl-Met, although the protective role of the amino acid was less pronounced than that of the hydroxy analogue. In conclusion, the diversion to the transsulfuration pathway means that this Met precursor is of greater value than previously thought, due to its capacity to improve intestinal homeostasis and the quality of poultry products destined for human consumption. 相似文献
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Gabriel Rosser Ruth E. Baker Judith P. Armitage Alexander G. Fletcher 《Journal of the Royal Society Interface》2014,11(97)
Most free-swimming bacteria move in approximately straight lines, interspersed with random reorientation phases. A key open question concerns varying mechanisms by which reorientation occurs. We combine mathematical modelling with analysis of a large tracking dataset to study the poorly understood reorientation mechanism in the monoflagellate species Rhodobacter sphaeroides. The flagellum on this species rotates counterclockwise to propel the bacterium, periodically ceasing rotation to enable reorientation. When rotation restarts the cell body usually points in a new direction. It has been assumed that the new direction is simply the result of Brownian rotation. We consider three variants of a self-propelled particle model of bacterial motility. The first considers rotational diffusion only, corresponding to a non-chemotactic mutant strain. Two further models incorporate stochastic reorientations, describing ‘run-and-tumble’ motility. We derive expressions for key summary statistics and simulate each model using a stochastic computational algorithm. We also discuss the effect of cell geometry on rotational diffusion. Working with a previously published tracking dataset, we compare predictions of the models with data on individual stopping events in R. sphaeroides. This provides strong evidence that this species undergoes some form of active reorientation rather than simple reorientation by Brownian rotation. 相似文献
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As redevelopment and gentrification strategies globally continue to be aimed at attracting wealthier residents and consumers in an effort to drive economic growth, concerns for and interventions in the interests of social equity appear decreasingly relevant. Government, private sector and community organisations have of course worked together in different times and places to implement programs that are more rather than less inclusive – the variations always depending on the spatial politics of the context. This paper examines contemporary discourses and practices of place-making in Melbourne, and asks whether ways of thinking about urban redevelopment as place-making in this time and place are likely to enable the inclusion of social equity in these urban “improvements”. 相似文献
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Complementing retrofit with engagement: exploring energy consumption with social housing tenants 下载免费PDF全文
Cathrine V. Jansson‐Boyd Rosalyn A. V. Robison Ruth Cloherty Carlos Jimenez‐Bescos 《国际能源研究杂志》2017,41(8):1150-1163
Councils and social housing organisations are looking to retrofit as a way to make their housing more energy efficient. Previous studies on energy use in social housing have generally focussed on the technological aspects (such as the potential savings possible by retrofitting this class of housing across the UK) or have involved one‐off interventions or measures. During a 2‐year period, we worked with previously homeless people to reduce their energy consumption. The 32 participants lived in small blocks of flats (owned by a social housing organisation) that underwent retrofitting with air source heat pumps. We ran a three‐phase tenant engagement programme to compare a range of approaches aimed at energy reduction. It was found that education, social norms and self‐awareness are all key components when it comes to initiating environmentally responsible behaviours. The three approaches complemented each other, and these ought to be considered alongside technology provision if the aim is to reduce energy consumption. A number of reflections on the implementation of medium‐term tenant engagement programmes are also presented. Copyright © 2016 John Wiley & Sons, Ltd. 相似文献
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Teng Xiao Weipan Cui Min Cai Wai Leung James W. Anderegg Joseph Shinar Ruth Shinar 《Organic Electronics》2013,14(1):267-272
We demonstrate the utility of a low-cost cesium iodide interlayer spun from an aqueous or 2-ethoxyethanol solution on ITO in inverted polymer solar cells of the structure ITO/CsI/P3HT:PCBM/MoO3/Al, where P3HT is poly(3-hexylthiophene) and PCBM is [6,6]-phenyl-C60-butyric acid methyl ester. The power conversion efficiency (PCE) of optimized cells was ~3.4%, comparable to that we obtained for inverted cells with Cs carbonate. The thickness of the CsI film was adjusted by varying the solution concentration. The concentration affected the surface morphology of P3HT:PCBM and the density of fractal-like aggregates (possibly related to the presence of Cs and film fabrication conditions) formed near the anode, as revealed by scanning electron microscopy. Auger analysis indicated a P3HT-rich surface. Optimization of the cells was achieved also by varying the thickness of the MoO3 and the drying/annealing conditions of the active layer, as was evident from the current–voltage characteristics, external quantum efficiency spectra, and PCE. The cells with the CsI interlayer were compared additionally to cells with CsCl or CsF interlayers (with a PCE of up to ~2.7%), which were inferior to the comparable cells with Cs2CO3 or CsI. The surface concentrations of Cs and the halide on ITO were monitored using X-ray photoelectron spectroscopy. The iodine level was low with the Cs:I ratio exceeding 8:1. In contrast, the Cs:Cl ratio was ~1.4:1 and the Cs:F ratio was ~1:1; the Cs2CO3 decomposed partially, as expected. Therefore, for CsI, as is the case for Cs2CO3 but not for CsF, Cs–O bonds are formed at the surface. Such bonds on ITO are important in modifying the ITO work function, improving the cell performance. The results indicate that spin coating solutions of the high polarity CsI is a promising and easy approach to introduce Cs–O on ITO in inverted structures for increased electron extraction from PCBM and possibly hole extraction from the P3HT-rich surface at the anode. 相似文献
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