Cytobiological studies on hemocyanin metabolism in the branchial heart complex of the common cuttlefish Sepia officinalis (Cephalopoda, Dibranchiata)

The present study confirms previous investigations that demonstrated a high copper content in the branchial heart and its appendage, and that gave the first indication that this organ complex might be involved in hemocyanin metabolism in Sepia officinalis L. Immunocytochemical localization of hemocyanin molecules within the endocytotic lysosomal system of the ovoid cells and tracer experiments with 125I-labeled Sepia hemocyanin suggest its endocytotic uptake. Energy-dispersive X-ray microanalysis and histochemical methods reveal a high copper content within the ovoid cells of the branchial heart. In view of the turnover of the respiratory pigment in the branchial heart of Sepia officinalis L., we believe that the ovoid cells are a site of hemocyanin catabolism.     

Multi-window spectrum estimation — A linear algebraic approach

The purpose of this paper is to elucidate the multi-window method for spectral estimation and sinusoid detection. The multi-window method, devised by D. J. Thomson, has many features that distinguish it from other spectrum estimation techniques. It has an elegant derivation, starting from first principles and using optimality arguments. It lends itself to performance analysis and provides a built-in measure of its reliability. In contrast to Thomson's integral equation derivation, we use linear algebraic methods both to treat the problem and to develop the solution. In addition to the tutorial, we present an overview of published generalizations and analyses of the method.     

Freud's views and the changing perspective on femaleness and femininity: What my female analysands taught me.

Examines Freud's views on female psychosexual development and femininity. The effect of Freud's patriarchal bias on the manner in which his followers analyzed women and the goals they set for the analysis of women are shown via vignettes. The feminist reexamination of previously accepted Freudian postulates yielded an examination of countertransference so that women began to be listened to during their analyses rather than told how it is and should be. Analysis of the pathological conformity to gender stereotypes and to gender mythologies is considered, as these determine not only the external realities in which women and men live but also the content and shape of the psychic world of each gender. Vignettes illustrate technical suggestions applicable to the analysis of women. New findings are discussed. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Social phobia: A comparison of specific and generalized subtypes and avoidant personality disorder.

The validity of the social phobia subtype distinction was examined in a large sample of carefully diagnosed social phobics (N?=?89). Generalized and specific subtypes were diagnosed reliably, and the generalized subtype showed a consistent pattern of greater symptom severity than did the specific subtype. In addition, generalized social phobics with and without avoidant personality disorder were compared, and a difference was found for only 1 of 4 parameters. The results are discussed in terms of the validity of subtyping in social phobia and the diagnostic boundary between social phobia and avoidant personality disorder. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Sexuality after spinal cord injury: A conceptual model based on women's narratives.

Objective: To investigate how women experience and conceptualize their sexuality after traumatic spinal cord injury (SCI). Research Method: Semistructured interviews and member checks with 24 women with SCI (ages 18-67) were conducted and content analyzed. Results: A conceptual model of sexual domains is proposed. Proposed domains are self- versus other focus, genital versus whole-body focus, physical versus holistic intimacy, sexuality as bodily versus mental phenomenon, exuberance versus negativity, and past versus present focus. Domains are defined and illustrated with narrative excerpts. They are conceptualized as fluid and nonexclusive. Conclusion: Endorsement of domains can change through ongoing adjustment to injury and life events. Clinical implications and suggestions for future research are provided. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Privacy in the private sphere

This article examines the issue of privacy within the home as a way of exploring the contradiction between feminist views that women and men experience the home differently ‐ and indeed that women may find the home oppressive ‐ and Saunders’ recent (1990) evidence that men and women express similar and equally strong positive sentiments about their home. We conclude that privacy within the home is negotiated within the wider framework of familial ideology and the ideals of ‘home’ and the companionate marriage’, so that within the home there is typically differential access to privacy for adults and children, and men and women.     

Quantitative HIV-1 RNA as a marker of clinical stability and survival in a cohort of 302 patients with a mean CD4 cell count of 300 x 10(6)/l

OBJECTIVE: To analyse plasma HIV-1 RNA levels as a marker of clinical stability and survival in a cohort of HIV-infected patients whose time of seroconversion is unknown. DESIGN: Retrospective cohort study. SETTING: Retrovirology laboratory and AIDS Unit in a teaching hospital. PATIENTS: A total of 916 samples from 302 patients, most on antiretroviral therapy, were analysed. Mean initial CD4 cell counts and HIV-1 RNA were 299 x 10(6)/l (range: 0-1600) and 134,261 copies/ml (range: < 200-4,300,000), respectively. Sixty-six cases had been diagnosed previously with AIDS. METHODS: Analysis of progression to AIDS and survival, according to initial and longitudinal viral load (VL) and CD4 cell count measurements was performed by Kaplan-Meier test. Relative risks were calculated by Cox's proportional hazards model. RESULTS: During a mean follow-up of 444 +/- 309 days, 29 patients developed AIDS and 21 died. Relative risk (RR) of progression related to the group with VL < 35,000 was: 10.4 when CD4 > or = 250 x 10(6)/l and VL > or = 35,000 (P = 0.001); and 45.3 when CD4 < 250 x 10(6)/l and VL > or = 35,000 (P < 0.0001). Cumulative probability of progression was: 0%, 0% and 12.3%, at the first, second and third year respectively, for patients with all their sequential VL determinations < 60,000; and 13.3%, 34.7% and 79.3% for patients who did not maintain VL values always < 60,000 (RR = 23; P < 0.0001). The minimum value of VL that reached statistical significance for the survival analysis was 100,000 copies/ml (P < 0.0001). CONCLUSIONS: VL > or = or < 35,000 is a better discriminant for progression than a CD4 cell count > or = or < 250 x 10(6)/l. Sequential VL determinations < 60,000 are associated with a better prognosis.     

Increased interhemispheric interaction is associated with earlier offset of childhood amnesia.

Experiment 1 found that mixed-handedness, which is associated with increased interaction between the left and right cerebral hemispheres relative to strong right-handedness, was associated with an earlier offset of childhood amnesia. In Experiment 2, bilateral saccadic eye movements, which have been shown to enhance interhemispheric interaction, were also associated with an earlier offset of childhood amnesia. These results build upon a growing body of research indicating an interhemispheric basis for the retrieval of episodic memories. Moreover, the results of Experiment 2 suggest that interhemispheric interaction has its effect on the retrieval, not encoding, of episodic memories. (PsycINFO Database Record (c) 2010 APA, all rights reserved)