Grundrechtsschutz im Europa des Lissaboner Vertrags

Nachdem als letzter Mitgliedstaat der Europ?ischen Union auch Tschechien im November 2009 den Lissaboner Vertrag ratifiziert hatte, konnte das Vertragswerk¹ zum 01. Dezember 2009 in Kraft treten. Seither sind allerdings die mit der neuen Rechtsgrundlage der Europ?ischen Union verbundenen vielf?ltigen Wirkungen kaum ins Bewusstsein der europ?ischen ?ffentlichkeit gelangt. Sie werden von den globalen Banken- und Wirtschaftsproblemen sowie von der aktuellen Krise der europ?ischen W?hrungsunion überlagert, die die nationalen Politiken der EU-Mitgliedstaaten und die gemeinschaftliche europ:aische Politik vor gro?e Herausforderungen stellen und deren Aufmerksamkeit in hohem Ma?e in Anspruch nehmen. Es mag also noch dauern, bis Europa in absehbarer Zeit und hoffentlich ohne an seinen politischkonstitutiven Fundamenten Schaden zu nehmen die aktuellen Krisen überwunden haben wird. Erst dann dürfte den Bürgerinnen und Bürgern Europas deutlicher werden, dass mit dem Inkrafttreten des Vertrages von Lissabon eine unter mehreren Gesichtspunkten neue Epoche des Europ?ischen Integrationsprozesses begonnen hat. Das gilt nicht nur, aber vor allem für die Innen- und Rechtspolitik — für jene Bereiche europ?ischer Politik also, die die Herstellung des seit 1999 im Amsterdamer Vertrag avisierten „Raumes der Freiheit, der Sicherheit und des Rechts“ zum Ziel haben. Innerhalb dieser im hohen Ma?e grundrechtssensiblen Politikfelder wird die neue Epoche vor allem von erheblichen Ver?nderungen sowohl im materiellen, rechtlichen als auch im institutionellen, gerichtlichen Schutz der Grund- und Freiheitsrechte der europ?ischen Bürgerinnen und Bürger gepr?gt sein.     

Influence of geometry and solids concentration on the hydrodynamics and mass transfer of a rectangular airlift reactor for marine sediment and soil bioremediation

Hydrodynamics and mass transfer characteristics of a three-phase airlift reactor were studied in a rectangular split-vessel reactor and using an air-seawater-marine sediment system. Experiments were conducted over a range of downcomer to riser cross-sectional area ratios (A_D/A_R = 0.65 to 1.0) for two-phase systems and for five sediment concentrations (5 to 25% w/v) using marine sediments. The influence of higher sediment concentrations (30 to 50% w/v) was examined for A_D/A_R = 1. The presence of fine sediment particles in the system had little effect on hydrodynamic and mass transfer parameters compared to the two-phase systems up to 25% loading, decreasing at higher loadings. The airlift reactor was found to meet the dissolved oxygen demand needed for a contaminated sediment treatment process. Axial distribution of the particles was uniform along the riser and the downcomer. Correlations were developed that described the hydrodynamic and mass transfer behaviour for all experimental conditions examined.     

Atomic Friction Investigations on Ordered Superstructures

We review recent friction measurements on ordered superstructures performed by atomic force microscopy. In particular, we consider ultrathin KBr films on NaCl(001) and Cu(001) surfaces, single and bilayer graphene on SiC(0001), and the herringbone reconstruction of Au(111). Atomically resolved friction images of these systems show periodic features spanning across several unit cells. Although the physical mechanisms responsible for the formation of these superstructures are quite different, the experimental results can be interpreted within the same phenomenological framework. A comparison between experiments and modeling shows that, in the cases of KBr films on NaCl(001) and of graphene films, the tip-surface interaction is well described by a potential with the periodicity of the substrate which is modulated or, respectively, superimposed with a potential with the symmetry of the superstructure.     

Sensory profiles and preference analysis in ornamental horticulture: The case of the rosebush

The context of ornamental horticulture is considered in order to extend the techniques of sensory and preference evaluation by taking the rosebush as a plant model. In a preliminary study (Boumaza, Demotes-Mainard, Huché-Thélier, & Guérin, 2009), a sensory evaluation was conducted in order to set up a list of attributes. Subsequently, this list was adapted to assess 10 rosebushes. After the control of the panel performance using a multivariate strategy of analysis, the average scores were used in product mapping. The evaluation of the preferences with regard to these rosebushes was undertaken: 253 subjects were asked to rank the products by decreasing order of liking. Thereafter, the preference data were subjected to an internal preference mapping and a cluster analysis. Six homogeneous segments of consumers were eventually retained. By way of performing an external preference mapping, the average ranks were regressed upon the sensory attributes using principal component regression: the preferences of 67% of the consumers were satisfactorily explained by the attributes.     

Intra-muscular and inter-muscular variation in carbon turnover of ovine muscles as recorded by stable isotope ratios

In the case of muscle-based foods, the incorporation of dietary isotopic signals into muscle tissue is a dynamic process and it is not known whether all muscles, or locations within a muscle, have the same isotopic composition. Therefore, an experiment was conducted in which 28 lambs were switched from a control diet to an isotopically distinct experimental diet offered at two different energy allowances (EA). Small, albeit significant, differences were detected in tissue carbon (C) turnover within the muscle Longissimus dorsi. Inter-muscular comparison showed similar C half-lives for four of the five analysed muscles. The results also clearly demonstrated that the EA had a significant impact on intra- and inter-muscular C turnover. The findings of similar tissue C turnover of several muscles sold as meats and the comparable tissue-diet fractionation of the analysed muscles (both within the same EA) will enable scientists to analyse different meat samples according to availability without introducing large biases. However, EA must be considered a factor of uncertainty.     

Improved compressed sensing reconstruction for $$^{19}$$ F magnetic resonance imaging

Magnetic Resonance Materials in Physics, Biology and Medicine - In magnetic resonance imaging (MRI), compressed sensing (CS) enables the reconstruction of undersampled sparse data sets. Thus,...     

Bolus ingestion of white and green tea increases the concentration of several flavan‐3‐ols in plasma,but does not affect markers of oxidative stress in healthy non‐smokers

White tea (WT) is rich in flavan‐3‐ols as green tea (GT) and might provide health protective effects due to the strong antioxidant properties of flavan‐3‐ols. Since intervention studies with WT are lacking, we evaluated the effects of WT consumption on antioxidant status, antioxidant capacity and biomarkers of oxidative stress compared to water and GT. After an overnight fast, 70 healthy non‐smokers were randomized to consume 600 mL of WT, GT or water (control). Plasma (epi‐)catechin and epi(gallo)catechingallate, antioxidant capacity (Folin assay, trolox equivalent antioxidant capacity test), 8‐iso‐prostaglandin F_2α, ascorbic acid and uric acid were determined before and several times within 8 h after consumption. DNA strand breaks were measured in vivo and ex vivo (H₂O₂ stimulation) in leukocytes. Plasma flavan‐3‐ols significantly increased after WT and GT ingestion. Trolox equivalent antioxidant capacity was lower after 5 h in controls versus WT (p=0.031) and GT (p=0.005). Folin‐Ciocalteu reducing capacity, ascorbic and uric acid as well as markers of oxidative stress (8‐iso‐prostaglandin‐F_2α, DNA strand breaks) were not affected by the beverages. A short‐term increase of catechins does not change plasma antioxidant capacity in healthy subjects. Conclusions with respect to health protective effects of WT and GT on the basis of these biomarkers can, thus, not be drawn.     

Cellular Internalisation of an Inositol Phosphate Visualised by Using Fluorescent InsP5

When applied extracellularly, myo‐inositol hexakisphosphate (InsP₆) and myo‐inositol pentakisphosphate (InsP₅) can inhibit the growth and proliferation of tumour cells. There is debate about whether these effects result from interactions of InsP₆ and InsP₅ with intracellular or extracellular targets. We synthesised FAM‐InsP₅, a fluorescent conjugate of InsP₅ that allows direct visualisation of its interaction with cells. FAM‐InsP₅ was internalised by H1229 tumour cells, a finding that supports earlier reports that externally applied inositol phosphates can—perhaps surprisingly—enter into cells. Close examination of the process of FAM‐InsP₅ uptake suggests a mechanism of non‐receptor‐mediated endocytosis, which is blocked at 4 °C and probably involves interaction of the ligand with the glycocalyx. However, our results are difficult to reconcile with antiproliferative mechanisms that require direct interactions of externally applied InsP₅ or InsP₆ with cytosolic proteins, because internalised FAM‐InsP₅ appears in lysosomes and apparently does not enter the cytoplasm. Studies using FAM‐InsP₅ are less difficult and time‐consuming than experiments using InsP₅ or InsP₆, a factor that allowed us to analyse cellular uptake across a range of human cell types, identifying strong cell‐specific differences.