Inclusion of fatigue effects in human reliability analysis

The effect of fatigue on human performance has been observed to be an important factor in many industrial accidents. However, defining and measuring fatigue is not easily accomplished. This creates difficulties in including fatigue effects in probabilistic risk assessments (PRA) of complex engineering systems that seek to include human reliability analysis (HRA). Thus the objectives of this paper are to discuss (1) the importance of the effects of fatigue on performance, (2) the difficulties associated with defining and measuring fatigue, (3) the current status of inclusion of fatigue in HRA methods, and (4) the future directions and challenges for the inclusion of fatigue, specifically sleep deprivation, in HRA.     

Secondary population implementation in multi-objective evolutionary algorithm for scheduling of FMS

Any practical implementation of any multi-objective evolutionary algorithm (MOEA) must include a secondary population composed of all Pareto-optimal solutions found during its search process. Such an implementation with an active participation of solutions from the secondary population into the generational population of the genetic cycle is expected to improve the effectiveness of the MOEA. In this work, two kinds of secondary population, one with set of non-dominated solutions and another with a set of inferior solutions, accrued out of the generation cycles are constructed, and with different combinations of feeding of solutions from these two secondary populations, seven different implementation schemes are designed with an aim of intensifying the convergence and diversification capabilities of the genetic process of MOEA. All the schemes were implemented in a genetic algorithm-based MOEA designed to solve the scheduling problem with dual objectives for a flexible manufacturing system and tested with common experimental data. The performances of the schemes are compared, and the most appropriate implementation scheme is proposed.     

Rotational abrasive flow finishing (R-AFF) process and its effects on finished surface topography

The present study focus on abrasive flow finishing (AFF), a process that finishes complex internal and external geometries with the help of viscoelastic abrasive medium, while keeping in mind its low finish and material removal rates (MRR). Researchers have often strived to improve finishing rate and MRR. As an attempt to overcome the said limitations, this paper discusses rotational abrasive flow finishing (R-AFF) process wherein complete tooling is externally rotated and the medium reciprocates with the help of hydraulic actuators. In this study, preliminary experiments are conducted on Al alloy and Al alloy/SiC metal matrix composites (MMCs) at different extrusion pressures, and medium compositions are employed for finding optimum conditions of the same for higher change in roughness (ΔR_a). The same optimum conditions are used to study the effect of workpiece rotational speed on (ΔR_a), material removal (MR), change in workpiece hardness and surface topology. It is noted that as the workpiece rotational speed increases from 2 to 10 RPM, the experimental helix angle decreases from 22° to 9° and the helical path length increases from 67 to 160 mm. Based on these findings the mechanism of material removal of matrix and reinforcement in MMC using R-AFF have been proposed. Here the matrix material is removed by micro-cutting and three methods of material removal mechanisms for reinforcement are also explained. The scientific logic behind finishing mechanism of matrix and reinforcement, cross hatch patterns, helical path directions, micro-scratch (μ-scratch) width and depth variation with size, orientation and support that active abrasive grain obtains from neighboring abrasives is derived from scanning electron microscopy micrographs. Finally this study establishes that R-AFF can produce 44% better ΔR_a and 81.8% more MR compared to the AFF process. Accordingly, R-AFF generates micro cross hatch pattern on the finished surface that can improve lubricant holding capabilities.     

Hygromorphs: from pine cones to biomimetic bilayers

We consider natural and artificial hygromorphs, objects that respond to environmental humidity by changing their shape. Using the pine cone as an example that opens when dried and closes when wet, we quantify the geometry, mechanics and dynamics of closure and opening at the cell, tissue and organ levels, building on our prior structural knowledge. A simple scaling theory allows us to quantify the hysteretic dynamics of opening and closing. We also show how simple bilayer hygromorphs of paper and polymer show similar behaviour that can be quantified via a theory which couples fluid transport in a porous medium and evaporative flux to mechanics and geometry. Our work unifies varied observations of natural hygromorphs and suggests interesting biomimetic analogues, which we illustrate using an artificial flower with a controllable blooming and closing response.     

Effects of the synthetic condition on the stability,particle size and redox chemistry of nanoporous CoAlPO-34

This study focuses on the effect of the synthetic conditions on the stability, particle size, redox chemistry of cobalt into the framework of CoAlPO-34. It seems that the most sufficient pH for the substitution of Co into the framework of CoAlPO-34 was pH around 7.5 when the as-synthesized bifunctional catalyst has the best redox property. The pH of the initial gel has strong effect on the particle size of CoAlPO-34. The substitution of cobalt and redox chemistry were determined by: EXAFS combined with XRD, XANES, IR. Stability of the nanoporous catalyst studied by in situ XRD were also reported.     

Forthcoming Contributions

Table of Contents

Forthcoming Contributions     

Behavior of decomposition of rifampicin in the presence of isoniazid in the pH range 1-3

The extent of decomposition of rifampicin in the presence of isoniazid was determined in the pH range 1-3 at 37°C in 50 min, the mean stomach residence time. With increase in pH, the degradation initially increased from pH 1 to 2 and then decreased, resulting in a bell-shaped pH-decomposition profile. This showed that rifampicin degraded in the presence of isoniazid to a higher extent at pH 2, the maximum pH in the fasting condition, under which antituberculosis fixed-dose combination (FDC) products are administered. At this pH and in 50 min, rifampicin decomposed by ~ 34%, while the fall of isoniazid was 10%. The extent of decomposition for the two drugs was also determined in marketed formulations, and the values ranged between 13-35% and 4-11%, respectively. The extents of decomposition at stomach residence times of 15 min and 3 h were 11.94% and 62.57%, respectively, for rifampicin and 4.78% and 11.12%, respectively, for isoniazid. The results show that quite an extensive loss of rifampicin and isoniazid can occur as a result of interaction between them in fasting pH conditions. This emphasizes that antituberculosis FDC formulations, which contain both drugs, should be designed in a manner that the interaction of the two drugs is prevented when the formulations are administered on an empty stomach.     

Industry case studies in the use of immersive virtual assembly

In this paper, we report on two engineering case studies that have been conducted as part of a Virtual Assembly Technology Consortium. The objectives of the case studies were to determine if immersive virtual assembly capabilities allow industry assembly situations to be modelled and studied realistically, and to demonstrate the downstream value of the virtual assembly capabilities in areas such as ergonomics, assembly installation, process planning, installation, and serviceability. What is of special significance is that instead of modelling simplified problems or perceived representative situations, the case studies were constructed from actual assembly floor projects and situations encountered at industry member sites and with considerable participation from industry engineers and manufacturing shop floor personnel. Based on the success of the case studies, the consortium members inferred that virtual assembly methods are poised to move out of the realm of special projects and test scenarios to deployment in the actual design and manufacturing cycle. However, in order to be truly accepted in industry, there are still issues to be addressed in terms of ease of use, portability of the applications, and preparation of the models for the evaluations. Thus, the case studies added a new dimension to the exploration and understanding of how this new technology could be of practical value in industry.