Scattering on a ring of processors

In this note, we prove that the complexity of scattering in an oriented ring of p processors is (p - 1) (β + Lτ) where L is the length of the messages, β the communication startup, and τ the elemental propagation time.     

Efficient and Scalable Kinetic Resolution of Racemic 4‐Formyl[2.2]paracyclophane via Asymmetric Transfer Hydrogenation

Herein we wish to report a new non‐enzymatic kinetic resolution of racemic 4‐formyl[2.2]paracyclophane based on Noyori asymmetric transfer hydrogenations (KR‐ATH). Our approach, which provides an efficient access to enantiopure (R_p)‐ and (S_p)‐4‐formyl[2.2]paracyclophane (>99% ee, 39% and 41% isolated yields, respectively), is operationally simple and can be run on the gram‐scale thus confirming the practical applicability of this method.

     

Evolution of the AgCdO Contact Material Surface Microstructure with the Number of Arcs

This paper describes a study of the evolution of the AgCdO contact material surface microstructure as a function of the number of electrical arcs imposed on the switching surface. Five power switching devices were tested under different conditions. They were subjected to, respectively, 1, 2, 3, 10, and 100 electrical arcs under the same operating conditions: supply current of 400 A, circuit voltage of 28 V direct current (DC), and resistive load. For the analysis, a binocular microscope and a scanning electron microscope with an energy-dispersive x-ray spectrometer were used.     

Improvement of the in vitro digestible iron and zinc content of okra (Hibiscus esculentus L.) sauce widely consumed in Sahelian Africa

ABSTRACT:  The effects of the formulation (okra, fish, soumbala, extract of wood ash) and cooking time of okra sauce on total iron and zinc content and on their in vitro digestibility were evaluated following a Doehlert uniform shell design with 5 factors and 33 trials. Cooking time had no significant effect on in vitro digestible iron and zinc content, whereas formulation did. Each ingredient had a specific effect. Extract of wood ash, which is a source of soluble and digestible iron and zinc, is a good way of increasing the digestible mineral content of the dish. Okra, the main ingredient in this sauce, has a negative effect and should be added in moderate quantities (< 37.7% of the DM of the sauce). An optimization using the desirability function allows us to identify the optimal recipe that enabled the quantity of digestible iron to be doubled and the quantity of digestible zinc to be increased by one third. This recipe calls for a mixture of 37.7% okra, 26.3% dried fish, 18.5% soumbala, and 3.7% extract of wood ash cooked for 25 min.     

Validation of the performance of a GMO multiplex screening assay based on microarray detection

A new screening method for the detection and identification of GMO, based on the use of multiplex PCR followed by microarray, has been developed and is presented. The technology is based on the identification of quite ubiquitous GMO genetic target elements first amplified by PCR, followed by direct hybridisation of the amplicons on a predefined microarray (DualChip^® GMO, Eppendorf, Germany). The validation was performed within the framework of a European project (Co-Extra, contract no 007158) and in collaboration with 12 laboratories specialised in GMO detection. The present study reports the strategy and the results of an ISO complying validation of the method carried out through an inter-laboratory study. Sets of blind samples were provided consisting of DNA reference materials covering all the elements detectable by specific probes present on the array. The GMO concentrations varied from 1% down to 0.045%. In addition, a mixture of two GMO events (0.1% RRS diluted in 100% TOPAS19/2) was incorporated in the study to test the robustness of the assay in extreme conditions. Data were processed according to ISO 5725 standard. The method was evaluated with predefined performance criteria with respect to the EC CRL method acceptance criteria. The overall method performance met the acceptance criteria; in particular, the results showed that the method is suitable for the detection of the different target elements at 0.1% concentration of GMO with a 95% accuracy rate. This collaborative trial showed that the method can be considered as fit for the purpose of screening with respect to its intra- and inter-laboratory accuracy. The results demonstrated the validity of combining multiplex PCR with array detection as provided by the DualChip^® GMO (Eppendorf, Germany) for the screening of GMO. The results showed that the technology is robust, practical and suitable as a screening tool.     

The Active XML project: an overview

This paper provides an overview of the Active XML project developed at INRIA over the past five years. Active XML (AXML, for short), is a declarative framework that harnesses Web services for distributed data management, and is put to work in a peer-to-peer architecture. The model is based on AXML documents, which are XML documents that may contain embedded calls to Web services, and on AXML services, which are Web services capable of exchanging AXML documents. An AXML peer is a repository of AXML documents that acts both as a client by invoking the embedded service calls, and as a server by providing AXML services, which are generally defined as queries or updates over the persistent AXML documents. The approach gracefully combines stored information with data defined in an intensional manner as well as dynamic information. This simple, rather classical idea leads to a number of technically challenging problems, both theoretical and practical. In this paper, we describe and motivate the AXML model and language, overview the research results obtained in the course of the project, and show how all the pieces come together in our implementation. The first and third authors were partially funded by the European Project Edos. Work done when the second and third authors were at INRIA. Work done when the second and third authors were at INRIA.     

Mlcrolasers based on silica microspheres

Light can be confined efficiently in the high-Q, small-volume whispering-gallery-modes observed in silica microspheres. By coupling these microspheres to eroded optical fibers and fiber tips, direct mapping of the whispering-gallery modes has been achieved and the mode numbers have been assessed. The properties of these modes have allowed us to obtain laser action with very low thresholds in Nd-doped silica microspheres. Further projects in the field of non-linear optics and cavity quantum electrodynamics are described.     

Stereochemistry of the N-glycosylation sites in glycoproteins

The stereochemical features displayed by the N-glycosidic linkagein crystalline N-linked glycoproteins are analyzed. From thestatistical analysis of 44 different glycosylation sites belongingto 26 glycoproteins of the Brookhaven Protein Data Bank, a meanstandard geometry for the GlcNAc moiety, along with a rationalizationof its confornia-tional behavior, can be proposed. As for theglycopeptide linkage, the distribution of observed conformationshas been analyzed on the basis of molecular mechanics calculations.The rotamer distribution of the Asn side chains conforms tothat observed on non-glycosylated structures, and it agreeswith the pattern of flexible conformations gathered from NMRmeasurements. In characterizing the protein-glycan interactions,some hydrogen bonds occur. Stacking between the amphiphilicmoiety of the glycan and some surrounding aromatic, or at leasthydrophobic, amino acid residues is also found. When lookingat the secondary structure of the glycosylated peptide, only25% of the glycosylation sites correspond to situations whereAsn is located at the top of a ß-turn. Other typesof secondary structure exist which fulfil the spatial requirementof having the glycan exposed at the surface of the protein.These data can be compared with the most recent studies on thepeptide conformation which would be required for glycosylation.