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31.
Fiber-reinforced composite conical shells with given geometry and material properties are optimized for maximum fundamental frequency. The shells are assumed to be built using an advanced tow-placement machine, which allows in-plane steering of the fibers, resulting in a variable-stiffness structure. In this paper, different path definitions for variable-stiffness shells are provided and used to optimize conical shells for maximum fundamental frequency, while manufacturing constraints that apply for tow placement are taken into account in the process. The influence of manufacturing constraints on the performance is shown; and improvements of variable-stiffness conical shells over conventional, constant-stiffness shells are demonstrated.  相似文献   
32.
Objective: The objective of this study was to fabricate double-walled poly(lactide-co-glycolide) (PLGA) microspheres to increase encapsulation efficiency and avoid rapid release of hydrophilic drugs such as meglumine antimoniate.

Methods: In this study, double-walled and one-layered microspheres of PLGA were prepared using the emulsion solvent evaporation technique to better control the release of a hydrophilic drug, meglumine antimoniate (Glucantime®), which is the first choice treatment of cutaneous leishmaniasis. The effect of hydrophobic coating on microspheres' size, morphology, encapsulation efficiency and drug release characteristics was evaluated. Furthermore, the presence of antimony in meglumine antimoniate made it possible to observe the drug distribution within the microspheres' cross section by means of energy dispersive X-ray spectroscopy.

Results: Drug distribution images confirmed accumulation of the drug within the inner core of double-walled microspheres. In addition, these microspheres encapsulated the drug more efficiently up to 87% and demonstrated reduced initial burst and prolonged release compared to one-layered microspheres. These superiorities make double-walled microspheres an optimum candidate for sustained delivery of hydrophilic drugs.

Conclusion: Double-walled microspheres provide some advantages over traditional microspheres overcoming most of their limitations. Double-walled microspheres were found to be more efficient than their corresponding one-layered microspheres in terms of encapsulation efficiencies and release characteristics.  相似文献   

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This work describes a simulation package for detailed studies of biasing networks for bipolar transistors. A sophisticated transistor model is introduced which captures many second-order effects, but which causes convergence difficulties for many existing methods used for computing an operating point. Artificial parameter numerical continuation techniques are introduced, then, as a robust and efficient means of solving bias networks employing our model. Sensitivity studies and natural parameter continuation studies based on the computed operating point (or points) are also discussed.  相似文献   
35.
Mobile communications has seen an explosive growth in the past five years with the integration of communications devices and multimedia applications. Transport connections set up over wireless links are frequently plagued by such problems as a high bit error rate (BER), frequent disconnections of the mobile users, and low wireless bandwidth that may change dynamically. Proposed developments in B3G and 4G wireless services will further challenge researchers to come up with efficient devices that can handle the huge data transmission. Fast and low-power compression algorithms are greatly needed to accommodate the specification. This paper highlights and analyzes various next-generation image-compression algorithms developed on the basis of image transmission via a wireless channel. In addition, the performance comparisons between the proposed hardware implementations are shown. Two important findings are discovered: First, the high-speed reconfigurable devices called FPSoC are the best hardware implementation. Second, a vector-quantization-based VSPIHT algorithm offers the best solution of parallel processing in efficient hardware architecture. This article serves as a reference point for researchers developing image-compression algorithms for next-generation mobile-communications devices. Published in Russian in Radiotekhnika i Elektronika, 2008, Vol. 53, No. 8, pp. 950–963. The text was submitted by the authors in English.  相似文献   
36.
The notion of a ‘uniformly balanced’ realization for time-variable systems has been previously introduced. This representation is characterized by the fact that its controllability and observability grammians are equal and diagonal. Such a framework has many remarkable properties and leads to a setting where the subsystems can be taken as reduced model for time-variable systems. It turns out that once the stability of a subsystem is guaranteed, then the subsystem preserves many of the properties of the original system. In this paper, the stability of subsystems is fully explored.  相似文献   
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Cobalt molybdenum disulfide, (CoMoS2) catalysts are evaluated as active electrocatalysts for the production of hydrogen gas in acidic aqueous media. These highly-active hydrogen evolution reaction (HER) catalysts are obtained from pretreatment of ammonium tetrathiomolybdate (ATM) with different amines precursors, and characterized by x-ray diffraction (XRD), scanning electron microscopy (SEM) and their surface areas are determined by Brunauer–Emmett–Teller (BET) surface area analyses. Electrochemical studies indicate that these CoMoS2 materials exhibit enhanced catalytic performance for hydrogen gas production with overpotentials ranging from 0.127 to 0.144 V, which are significant less than CoMoS2 synthesized directly from ATM under the same synthetic techniques (0.173 V). These CoMoS2 catalysts are also stable in the presence of strong acidic media after a considerably long period of time (10 h) for maintaining their efficiencies for hydrogen gas evolution.  相似文献   
39.
Solar Home System (SHS) based rural electrification has experienced a considerable growth in Bangladesh since the start of the Rural Electrification and Renewable Energy Development Project (REREDP) in 2003. The initial target of 50,000 SHS installations in off-grid areas was achieved within 2.5 years, 3 years ahead of schedule. After achieving a revised target of 200,000 SHSs, ahead of schedule in early 2009, a new target of 1 million SHS installations by 2012 was set. The installation of about 0.5 million systems by March 2010 indicates that the current target may well be achieved before the deadline. The size of the SHS market and its impact on the regeneration of the rural economy make it necessary to investigate the quality and reliability of the installed SHSs, if the continued success of the initiative is to be maintained. This paper reports on the findings from a field-based technical appraisal of SHS installations in Bangladesh. Sixty geographically dispersed installation sites were visited. Physical characteristics of the SHSs and their system components were tested to ascertain compliance with and deviations from the approved specifications. Despite the overwhelming success of the REREDP project, the study revealed various shortcomings. Notable among these are: incompatible and sub-optimal component configurations, faulty installations and a lack of effective quality assurance mechanism. The findings are contextualized and the ways to address the identified shortcomings are discussed.  相似文献   
40.
Dietary fibre components, hydration properties and antioxidant activities such as 1,1‐diphenyl‐2‐picrylhydrazyl (DPPH) radical scavenging, reducing power, metal chelating and 2,2′‐azino‐bis,3‐ethyl‐benzo‐thiazoline‐6‐sulphonic acid (ABTS) radical scavenging activities of persimmon peel powders using different washing treatments (tap water at 20 °C and hot water) were investigated. Peel powder obtained from hot water‐washed peels (74.95 g per 100 g) had higher dietary fibre content than tap water‐washed (65.50 g per 100 g) and unwashed (60.99 g per 100 g) peels. The higher content of total phenolic and ascorbic acid were found in peel powder obtained from unwashed peels, whereas washed peels had more β‐carotene content. The EC50 values of scavenging DPPH and ABTS radical for peel powders obtained from unwashed, tap water‐washed and hot water‐washed peels were 75.44, 142.18 and 110.17 μg mL?1 respectively and 5.31, 5.34 and 5.39 μg mL?1 respectively. Therefore, hot water washing is recommended to obtain better quality products from persimmon peel for use as a fibre supplement.  相似文献   
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