黑龙江省速滑馆场地照明方案设计

体育建筑照明方案设计的关键在比赛场地的照明方案设计、其成功与否是体育建筑能否满足使用要求的主要技术指标之一，本文对黑龙江省速滑馆照明方案设计的各项技术数据进行了详细的介绍。     

上海包装行业基本情况

<正>一、行业基本情况 近些年来,在国民经济持续、快速、健康发展大环境中,作为以工业产品配套为主的上海包装工业,随之趋向正常、稳定发展新阶段,每年仍能保持10％左右的增长速     

目标管理--一种最佳管理方法

“目标管理”这一方法在我公司运用已有多年,其从不成熟走向成熟,逐步被广大员工所接受。这几年,通过公司实行目标管理,公司效益连年提高,1999年、2000年利税指标连续提高7％、工业增加值连续增长5％以上。在此我愿把公司在从事目标管理运行当中积累的经验及切身体会告诉大家,与企业     

Microstructure of Si Cones Prepared by Ar^＋—Sputtering Si／Mo Target

By Ar^ sputtering onto Si wafers which were surrounded by Mo plates.uniform cones over a large area on the Si surface were formed.Scanning electron microscopic study showed that the cones were formed on the entire surface of the Si wafer.The dimensions of the uniform cones were one micrometer in diameter and 5-6 micrometers high.They were further characterized by means of cross-sectional transmission electron microscopy,with the technique of micro-diffractions,It was found that the cone contained a pure Si regime and a Mo-rich regime.In the binary Mo-Si zone,we identified three distinct areas vertically:(1)domains of Mo-induced Si ordered structures,(2)a small volume of a new Mo3Si2 structural variant,intergrown with the Si ordered structure,and(3) a small amount of pure Mo nanoparticles covering the surface of the cones.The formation of the large and uniform cones may provide a new surface configuration for potential applications in surface science and technology.     

Reciprocal changes in p27(Kip1) and p21(Cip1) in growth inhibition mediated by blockade or overstimulation of epidermal growth factor receptors

Many human epithelial tumors express high levels of epidermal growth factor (EGF) receptors. A human-mouse chimeric version of anti-EGF receptor monoclonal antibody (mAb) C225, which blocks receptor activation and produces inhibition of cell proliferation, is currently being investigated in clinical trials. When cells bear high numbers of EGF receptors, either complete blockade of receptors with mAb 225 or full activation of receptors with EGF results in inhibition of proliferation. In the present study, we have explored the molecular mechanisms explaining how a receptor inhibitor, mAb 225, and a receptor activator, EGF, can both produce growth inhibition of A431 human squamous epithelial carcinoma cells. We reported previously that inhibition of A431 cells by EGF is associated with up-regulation of p21(Cip1). We now demonstrate that mAb 255-mediated inhibition is associated with up-regulation of p27(Kip1), which binds to and inactivates cyclin-dependent kinase-2 activity and produces cell cycle arrest in G1. Furthermore, inhibition by mAb 225 can be overcome by titrating the cultures with increasing concentrations of EGF, which is accompanied by a concurrent fall in the level of p27(Kip1). At properly titrated concentrations of mAb 225 and EGF, the inhibitory activities of both mAb 225 and EGF are counterbalanced and abolished. When EGF concentrations reach levels high enough to compete with mAb to produce near-saturating levels of receptor activation, p27(Kip1) falls below basal levels; however, the concomitant marked rise in the level of p21(Cip1) results in growth inhibition. Our data suggest that although p27(Kip1) and p21(Cip1) are induced and act independently, they play reciprocal roles in mediating inhibition of A431 cell growth by blockade of EGF receptors with mAb 225 and by activation of receptors with saturating concentrations of EGF.     

注水站最优控制原理

概述了油田注水站计算机最优节能控制理论，认为注水系统能上三部分组成：（１）注水泵驱动电机损耗；（２）注水泵损耗；（３）管网系统损耗，注水站优化节能的目标就是在满足配注方案的前提下，将上述３种损耗降至最小，给出了一种以注水系统效率为目标函数的注水站最优控制的原理和设计方法，采用这种方法来设计注水站的节能控制方案可取得较大的经济效益。     

测量聚合物薄膜厚度的一种简便方法

本文介绍了用准波导耦合ｍ线技术测量聚合物薄膜厚度的方法。测量结果表明，薄膜样品厚度的误差为３．６２×１０＾－２μｍ。并对测量精度作了分析和讨论。     

轮古40C井套管开窗侧钻小井眼定向钻井技术

在老井改造措施中,采用套管开窗侧钻比较普遍,而在侧钻过程中经常会遇到不同的地层压力系数,必须增加一层套管,这样就得用更小尺寸的钻头钻进,施工难度也随之加大。轮古40C井所遇到的正是此种情况。为了预防窗口小影响下步施工,在塔里木油田深井中,套管开窗侧钻一般采用锻铣套管开窗,为减少施工工序,该井使用了斜向器开窗,并在?152.4 mm井眼顺利下入了?127 mm尾管并固井,然后用?104.8 mm钻头钻达设计井深。通过该井的成功探索,说明使用一次性斜向器开窗侧钻是可行的;钻?104.8 mm小井眼时,防止发生钻具事故是关键,如果钻具脱落,首选公锥进行打捞。     

壳程结构对换热器性能影响的数值研究

在简化模型的基础上运用CFD数值模拟方法,对比研究了螺旋折流板和弓形折流板壳程结构和流动参量的变化对换热器整体流动与传热性能的影响。结果表明,2种结构对应的壳程压力损失和换热系数均随流量的增加而增大,而螺旋折流板结构的α/Δp参数明显大于弓形折流板,体现了螺旋折流板结构的优越性。这种特点对于现有生产工艺的增容改造具有重要意义,可以在不额外增加动力设备的前提下有效满足生产需要,节省能源消耗。