Indications that the Cgamma2 homology region is not a regular domain

The Cgamma2 homology region of rabbit IgG does not behave like a domain. Thus, there is no trans-interaction between the two Cgamma2 regions; instead there is an unusual cis-interaction between Cgamma2 and Cgamma3 regions. The observations were made on the plasmin digestion products Facb (IgG minus the Cgamma3 region) and pFc' (Cgamma3 region), which did not dissociate under neutral conditions but dissociated in 3M guanidine solution (that is, cis-interaction between Cgamma2 and Cgamma3). The Facb fragment split into subunits with equal molecular weights under neutral conditions on partial reduction and alkylation (that is, lack of trans-interaction between the two Cgamma2 in the molecule).     

On modified Runge-Kutta trees and methods

Modified Runge-Kutta (mRK) methods can have interesting properties as their coefficients may depend on the step length. By a simple perturbation of very few coefficients we may produce various function-fitted methods and avoid the overload of evaluating all the coefficients in every step. It is known that, for Runge-Kutta methods, each order condition corresponds to a rooted tree. When we expand this theory to the case of mRK methods, some of the rooted trees produce additional trees, called mRK rooted trees, and so additional conditions of order. In this work we present the relative theory including a theorem for the generating function of these additional mRK trees and explain the procedure to determine the extra algebraic equations of condition generated for a major subcategory of these methods. Moreover, efficient symbolic codes are provided for the enumeration of the trees and the generation of the additional order conditions. Finally, phase-lag and phase-fitted properties are analyzed for this case and specific phase-fitted pairs of orders 8(6) and 6(5) are presented and tested.     

Islet amyloid polypeptide in patients with pancreatic cancer and diabetes

Population-based psychiatric admission rates vary across geographic areas, but reasons for this variation are unknown. Insofar as Community Mental Health Centers (CMHCs) provide outpatient services that may deter the need for hospitalization, the presence and structural characteristics of CMHCs may have an impact on a population's psychiatric admission rates. This study uses small area analysis to examine how general hospital psychiatric admission rates are associated with CMHC characteristics. Based on a survey of all CMHCs in Iowa and corresponding small area variation data, it was found that population admission rates were higher in areas closer to the CMHC and lower in outlying catchment areas, adjusting for age, sex, and urban/rural differences in populations. There was little evidence that differences in staffing and service variables influenced admission rates, although greater CMHC staff coverage by social workers and psychiatric residents was associated with lower admission rates. The results suggest that CMHCs do not lower an area's hospitalization rate, and in fact, the presence of CMHCs may promote a "supplier-induced demand" phenomenon of higher admissions.     

Fourier methods for testing multivariate independence

Recently a power study of some popular tests for bivariate independence based on ranks has been conducted. An alternative class of tests appropriate for testing not only bivariate, but also multivariate independence is developed, and their small-sample performance is studied. The test statistics employ the familiar equation between the joint characteristic function and the product of component characteristic functions, and may be written in a closed form convenient for computer implementation. Simulations on a distribution-free version of the new test statistic show that the proposed method compares well to standard methods of testing independence via the empirical distribution function. The methods are applied to multivariate observations incorporating data from several major stock-market indices. Issues pertaining to the theoretical properties of the new test are also addressed.     

A new approach of goodness-of-fit testing for exponentiated laws applied to the generalized Rayleigh distribution

Goodness-of-fit statistics are considered which are appropriate for generalized families of distributions, resulting from exponentiation. The tests employ a variation of the data determined by the cumulative distribution function of the corresponding non-generalized distribution. The resulting test, which makes use of the Mellin transform of the transformed data, is shown to be consistent. Simulation results for the case of the generalized Rayleigh distribution show that the proposed test compares well with standard methods based on the empirical distribution function.     

The Combination of Two Control Strategies for Series Hybrid Electric Vehicles

With most countries paying attention to the environment protection, hybrid electric vehicles have become a focus of automobile research and development due to the characteristics of energy saving and low emission. Power follower control strategy (PFCS) and DC-link voltage control strategy are two sorts of control strategies for series hybrid electric vehicles (HEVs). Combining those two control strategies is a new idea for control strategy of series hybrid electric vehicles. By tuning essential parameters which are the defined constants under DC-link voltage control and under PFCS, the points of minimum mass of equivalent fuel consumption (EFC) corresponding to a series of variables are marked for worldwide harmonized light vehicles test procedure (WLTP). The fuel economy of series HEVs with the combination control schemes performs better compared with individual control scheme. The results show the effects of the combination control schemes for series HEVs driving in an urban environment.