关于中国放射源管理的建议

1　放射性废物管理方面( 1 )应当建立一个国家级的废放射源管理战略。此战略应包括过去、现在和将来产生的所有放射性废物。此废物管理战略可以由国家指定的委员会来制订。该委员会可以包括来自主要废物的产生单位、废物管理机构和相应的审管部门的代表。此战略应当涵盖技术选择 (处理和处置 )和基础架构 (废物管理机构和基金 )。( 2 )放射性废物管理 ,包括废密封源管理。要求有专门的技术设施和特别训练的人员。为避免基础结构和人力资源重复设置 ,可以考虑单一的废物管理机构。该机构可设有区域性的分支机构 ,也可以设有专门的部门管理来…     

Ausbau des Stichkanals nach Salzgitter von SKS‐km 3,550 bis 14,918

Expansion of the branch channel to Salzgitter from SKS‐km 3,550 to 14,918 The branch channel to Salzgitter will be extended to the waterway category Vb in the next years. This will enable inland waterway vessels with a width of 11,45 m and a loaded draft of 2,80 m to run it without limitations. The reaches Wedtlenstedt and Üfingen will be extended in most areas to a trapezoidal cross section with a width at water level of 36,90 m and a water depth of 4,00 m. The exit basins of the locks will be extended on one side. Overall about 1 000 000 m² of soil will be moved. About 300 000 m² of clay sealing and 460 000 m² of rip‐rap will be installed. Three culverts have to be replaced by new constructions to adapt to the new cross section of the channel. In addition two bridges will be modified to allow for a clearance of 5,25 m. At present the plan approval procedure is carried out. It is expected to achieve the plan approval order in 2017. The construction is planned to start in 2018. Completion is scheduled for 2024.     

Protective coatings on extensible biofibres

Formulating effective coatings for use in nano- and biotechnology poses considerable technical challenges. If they are to provide abrasion resistance, coatings must be hard and adhere well to the underlying substrate. High hardness, however, comes at the expense of extensibility. This property trade-off makes the design of coatings for even moderately compliant substrates problematic, because substrate deformation easily exceeds the strain limit of the coating. Although the highest strain capacity of synthetic fibre coatings is less than 10%, deformable coatings are ubiquitous in biological systems. With an eye to heeding the lessons of nature, the cuticular coatings of byssal threads from two species of marine mussels, Mytilus galloprovincialis and Perna canaliculus, have been investigated. Consistent with their function to protect collagenous fibres in the byssal-thread core, these coatings show hardness and stiffness comparable to those of engineering plastics and yet are surprisingly extensible; the tensile failure strain of P. canaliculus cuticle is about 30% and that of M. galloprovincialis is a remarkable 70%. The difference in extensibility is attributable to the presence of deformable microphase-separated granules within the cuticle of M. galloprovincialis. The results have important implications in the design of bio-inspired extensible coatings.     

Thermal and elastic properties of poly(vinyl chloride) (PVC) + chlorinated polyethylene (CPE) blends

Eight types of PVC + CPE blends with different weight ratios (PVC/CPE = 100/0, 90/10, 80/20, 60/40, 40/60, 20/80, 10/90, and 0/100) are tested. Data on the heat conductivity, thermal diffusivity, and heat capacity of the blends investigated are reported. Primary attention is paid to the structural approach for effective elastic constants: bulk, shear, and Young's modulae. The blends are considered as random mixtures of two isotropic constituents. It is found that the elastic moduli may be well represented by the Kerner and Budiansky equations.     

Release of liposome-encapsulated calcein from liposome entrapping gelatin-carboxymethylcellulose films: a presentation of different possibilities

Liposome entrapment in films consisting of gelatin (GEL) or GEL/sodium carboxymethylcellulose (NaCMC) mixtures, as a method to alter drug release kinetics from polymeric films and/or incorporate sensitive bioactive molecules in solid films, was investigated. Bulk or thin complex (liposome trapping) films were formed by crosslinking (with glutaraldehyde) solutions of GEL or GEL/NaCMC in presence of calcein-encapsulating or rhodamine-labeled liposomes (Rho-Lip). Rho-Lip were observed by confocal microscopy to be homogenously distributed in the films. Calcein release from films was evaluated for periods up to 25 d, and it was found that several possibilities, concerning the release of the liposome-encapsulated molecule from the films, are offered; (i) Release can be sustained, if large liposomes are entrapped in the films. In this case the liposome-encapsulated molecules are released from the films only after they have been released from the vesicles, and the release can be controlled by modifying the film composition, the network density and/or the film geometry. (ii) Intact small unilamellar liposomes (SUV) can be released from the polymeric films depending on their swelling degree. The later can be controlled by modulating the film composition and amount of crosslinker. Film composition also affects the integrity of the film-entrapped liposomes during the crosslinking process, possibly due its effect on the density of the polymeric network of the film.     

Arsonoliposomes: novel nanosized arsenic-containing vesicles for drug delivery

Natural and synthetic arsenolipids, have been discovered, synthesized, and evaluated for their biological activity. Arsonolipids, are analogs of phosphonolipids, in which P has been replaced by As. The synthesis of arsonolipids has been explored and a simple one-pot method with high yield is currently available for their preparation. However, although arsonolipids posses interesting biophysical and biochemical properties their anticancer or antiparasitic activity is not considered adequate for therapeutic applications. But when arsonolipids are incorporated in liposomes, the vesicles formulated have interesting possibilities, as seen in a number of studies. In cell culture studies, nanosized arsonolipid-containing liposomes or else arsonoliposomes, showed increased toxicity against cancer cells (compared to that of arsenic trioxide) but at the same time were less toxic than arsenic trioxide for normal cells. Furthermore, arsonoliposomes also demonstrate antiparasitic activity in vitro. Nevertheless, As is rapidly cleared from blood after in vivo administration of arsonoliposomes, and this will highly limit possible therapeutic applications. In addition, the fact that arsonoliposomes were observed to aggregate and subsequently fuse into larger particles in presence of cations, may also be considered as a problem. Thereby, methods to modulate the stability of arsonoliposomes and, perhaps, their in vivo distribution (as surface property modification) are currently being investigated. In very recent experiments it has been shown that arsonoliposome pegylation results in the formation of liposomes with very high membrane integrity. In addition, pegylation results in increased physical stability of arsonoliposomes and abolishment of cation-induced aggregation and fusion. Nevertheless, further in vivo studies are required in order to prove if pegylation alters arsonoliposome in vivo kinetics in a positive way, without affecting their activity. From studies performed thus far it is concluded that arsonoliposomes are nanosized-vesicles with interesting properties that justify further exploitation towards the development of therapeutic systems for cancer or parasitic diseases.     

Symptoms of professional burnout: A review of the empirical evidence.

Reviews empirical literature, 1974–1984, concerning symptoms of burnout among human service professionals. Symptoms of burnout are grouped into 5 categories: physical, emotional, behavioral, interpersonal, and attitudinal. It is concluded that burnout is associated with poor physical health; depression; job turnover and unproductive work behaviors; problematic interpersonal relations; and negative attitudes, especially with regard to job satisfaction. Problems with research include lack of operational definition, defects in instruments, and impressionistic findings. Future needs include further exploration of content, attention to interactive effects, and alternative methodologies. (French abstract) (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

DISCOVERING ROBUST EMBEDDINGS IN (DIS)SIMILARITY SPACE FOR HIGH‐DIMENSIONAL LINGUISTIC FEATURES

Recent research has shown the effectiveness of rich feature representation for tasks in natural language processing (NLP). However, exceedingly large number of features do not always improve classification performance. They may contain redundant information, lead to noisy feature presentations, and also render the learning algorithms intractable. In this paper, we propose a supervised embedding framework that modifies the relative positions between instances to increase the compatibility between the input features and the output labels and meanwhile preserves the local distribution of the original data in the embedded space. The proposed framework attempts to support flexible balance between the preservation of intrinsic geometry and the enhancement of class separability for both interclass and intraclass instances. It takes into account characteristics of linguistic features by using an inner product‐based optimization template. (Dis)similarity features, also known as empirical kernel mapping, is employed to enable computationally tractable processing of extremely high‐dimensional input, and also to handle nonlinearities in embedding generation when necessary. Evaluated on two NLP tasks with six data sets, the proposed framework provides better classification performance than the support vector machine without using any dimensionality reduction technique. It also generates embeddings with better class discriminability as compared to many existing embedding algorithms.