Work hours, workload, sleep and fatigue in Australian Rail Industry employees

Research suggests that less than 5 h sleep in the 24 h prior to work and/or more than 16 h of wakefulness can significantly increase the likelihood of fatigue-related impairment and error at work. Studies have also shown exponential safety declines with time on shift, with roughly double the likelihood of accident or injury after 10 h relative to the first 8 h. While it is acknowledged that reduced sleep, increased wakefulness and longer work hours produce work-related fatigue, few studies have examined the impact of workload on this relationship. Studies in the rail industry have focused on drivers. This study investigated fatigue in a large sample of Australian Rail Industry Employees. Participants were from four companies (n = 90: 85m, 5f; mean age 40.2 ± 8.6 y). Data was analysed for a total of 713 shifts. Subjects wore wrist actigraphs and completed sleep and work diaries for 14-days. They also completed the Samn–Perelli Fatigue Scale at the beginning and end of shifts, and the NASA-TLX workload scale at least twice during each shift. Average (±SD) sleep length (7.2 ± 2.6 h), prior wake at shift end (12.0 ± 4.7 h), shift duration (8.0 ± 1.3) and fatigue (4.1 ± 1.3, “a little tired, less than fresh”) were within limits generally considered acceptable from a fatigue perspective. However, participants received 5 h or less sleep in the prior 24 h on 13%, were awake for at least 16 h at the end of 16% and worked at least 10 h on 7% of shifts. Subjects reported that they felt “extremely tired, very difficult to concentrate,” or “completely exhausted, unable to function effectively” on 13% of shifts. Sleep length (OR = 0.88, p < 0.01), shift duration (OR = 1.18, p < 0.05), night shift (REF = morning shift, OR = 2.12, p < 0.05) and workload ratings (OR = 1.2, p < 0.05) were significant predictors of ratings of extreme tiredness/exhaustion (yes/no). While on average, sleep loss, extended wakefulness, longer work hours and work-related fatigue do not appear problematic in this sample, there is still a notable percentage of shifts that are likely to be associated with high levels of work-related fatigue. Given the size of the Australian Rail Industry, with thousands of shifts occurring each day, this is potentially of operational concern. Further, results indicate that, in addition to sleep length, wakefulness and work hours, workload significantly influences fatigue. This has possible implications for bio-mathematical predictions of fatigue and for fatigue management more generally.     

The minimum positional error incurred by any connectivity-based positioning algorithm for mobile wireless systems

A very important problem in many wireless ad-hoc networks, including wireless sensor networks, is positioning or the determination of geographical locations of the wireless nodes. Positioning is used both in infrastructural aspects of sensor networks, like geographic routing and topology maintenance, and in applications like wildlife tracking. Connectivity-based positioning algorithms in mobile wireless systems are studied in this work. These algorithms compute node positions based only on the connectivity, i.e. the neighborhood information of each node. Many algorithms have been proposed for positioning in stationary node systems and bounds on positional error of algorithms have been derived. The design and analysis of positioning algorithms for mobile node systems is a more challenging problem. Node mobility increases the amount of positional information available to a positioning algorithm. The work in this paper establishes a bound on the positional error for connectivity-based algorithms in mobile systems. The formulation from the analysis is used to investigate the benefit of this additional positional information on reducing positional error. There is a limit to the usefulness of positional information from previous node positions due to movement. This captures an important performance tradeoff: historical positional information can yield reduced positional error but requires more connectivity information from the network which requires greater computational resources.     

Mitochondria: A mirror into cellular dysfunction in heart disease

Cardiovascular (CV) disease is the single most significant cause of morbidity and mortality worldwide. The emerging global impact of CV disease means that the goals of early diagnosis and a wider range of treatment options are now increasingly pertinent. As such, there is a greater need to understand the molecular mechanisms involved and potential targets for intervention. Mitochondrial function is important for physiological maintenance of the cell, and when this function is altered, the cell can begin to suffer. Given the broad range and significant impacts of the cellular processes regulated by the mitochondria, it becomes important to understand the roles of the proteins associated with this organelle. Proteomic investigations of the mitochondria are hampered by the intrinsic properties of the organelle, including hydrophobic mitochondrial membranes; high proportion of basic proteins (pI greater than 8.0); and the relative dynamic range issues of the mitochondria. For these reasons, many proteomic studies investigate the mitochondria as a discrete subproteome. Once this has been achieved, the alterations that result in functional changes with CV disease can be observed. Those alterations that lead to changes in mitochondrial function, signaling and morphology, which have significant implications for the cardiomyocyte in the development of CV disease, are discussed.     

A biomechanical analysis of anterior load carriage

Front load carriage is a common occupational task in some industries (e.g. agriculture, construction), but, as compared to lifting tasks, relatively little research has been conducted on the biomechanical loading during these activities. The focus of this study was to explore the low back biomechanics during these activities and, specifically, to examine the effects of load height and walking speed on trunk muscle activity and trunk posture. Eleven male participants participated in two separate front load-carriage experiments. The first experiment called for carrying a barbell (with weight corresponding to 20% of elbow flexion strength) at three heights (knuckle height, elbow height and shoulder height) at a constant horizontal distance from the spine. The second experiment called for participants to carry a bucket of potatoes weighing 14 kg at the same three heights, but with no further restrictions in technique. In both experiments, the participants performed this task while either standing still or walking at a self-selected speed. As they performed these tasks, the activity levels of the right-side muscle of the rectus abdominis, external oblique, biceps brachii, anterior deltoid and three levels (T9, T12 and L3) of the erector spinae were sampled. Mid-sagittal plane trunk posture was also quantified using three magnetic field-based motion sensors at T9, T12 and L3. The results showed a significant effect of both walking speed and load height on trunk posture and trunk muscle activity levels in both the barbell and bucket experiments. In the barbell experiment, the walking trials generated 43% more trunk muscle activity than the standing trials. Trials at shoulder height produced 11% more muscle activity than trials at elbow height in the T9 erector spinae muscles and 71% more muscle activity in the anterior deltoid. In the bucket experiment, trunk muscle activity responded in a similar fashion, but the key result here was the quantification of the natural hyperextension posture of the spine used to balance the bucket of potatoes. These results provide insight into muscle activation patterns in dynamic settings, especially (load) carrying biomechanics, and have implications in industrial settings that require workers to carry loads in front of their bodies.     

A proteome analysis of the dorsolateral prefrontal cortex in human alcoholic patients

Alcoholic patients commonly experience cognitive decline. It is postulated that cognitive dysfunction is caused by an alcohol-induced region-selective brain damage, particularly to the prefrontal region, and grey and white matter may be affected differently. We used a proteomics-based approach to compare protein expression profiles of the dorsolateral prefrontal cortex (Brodmann area 9 (BA9)) from human alcoholic and healthy control brains. Changes in the relative expression of 110 protein 'spots' were identified in the BA9 grey matter, of which 54 were identified as 44 different proteins. In our recent article, 60 protein spots were differentially expressed in the BA9 white matter and 18 of these were identified (Alexander-Kaufman, K., James, G., Sheedy, D., Harper, C., Matsumoto, I., Mol. Psychiatry 2006, 11, 56-65). Additional BA9 white matter proteins are identified here and discussed in conjunction to our grey matter results. Thiamine-dependent enzymes transketolase and pyruvate dehydrogenase (E1β ubunit) were among the proteins identified. To our knowledge, this is the first time a disruption in thiamine-dependent enzymes has been demonstrated in the brains of 'neurologically uncomplicated' alcoholics. By identifying protein expression changes in prefrontal grey and white matter separately, hypotheses may draw upon more mechanistic explanations as to how alcoholism causes the structural alterations associated with alcohol-related brain damage and cognitive dysfunction.     

Impact of an organizational control policy on absenteeism, performance, and satisfaction.

Examined the impact of an organizational control policy based on the concept of "legal compliance" with established organizational norms on 2 behavioral measures--absenteeism and performance--and 2 attitudinal measures of satisfaction. The control policy was experimentally manipulated in each of 2 experimental groups totaling 297 undergraduates. In one group, a compulsory attendance policy followed by a noncompulsory policy was employed, while in the other the sequence of administering the policies was reversed. Attendance, performance, and satisfaction measures were used as criteria in analyses of variance. Results indicate that a control policy based on legal compliance significantly improved attendance and performance and did not alter satisfaction levels. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

Electrically small antenna elements using negative permittivity resonators

We show how resonators composed of negative permittivity materials can form the basis of effective small antenna elements. A quasi-static analysis of the resonant properties of a sub-wavelength negative permittivity sphere predicts that such a resonator will have a Q-factor that is only 1.5 times the Chu limit, matching the performance of other known electrically small spherical antenna designs, such as the folded spherical helix and the spherical capped dipole. Finite element simulation is used to demonstrate an impedance-matched radiating structure formed by coupling the resonator (a half-sphere above a ground plane) to a 50 ohm coaxial transmission line, where the coupling is mediated by a small conducting stub extending partially into the half-sphere. The resulting antenna has a ka<0.5, and its bandwidth and efficiency performance corresponds well to that predicted by the quasi-static analysis of the resonator.     

Multiculturalism: Questions, Not Answers.

A reply by Richard B. Stuart regarding the comment by Stolle, Hutz, and Sommers-Flanagan (see record 2005-13212-019). The American Psychological Association (APA) guidelines on multiculturalism (APA, 2002b) exhort psychologists to recognize and control their personal biases and to strive to "apply culturally appropriate skills in clinical and other applied psychological practices" (p. 3). My article (see record 2004-10365-001) offered 12 suggestions aimed at helping psychologists follow these mandates. It was motivated by the fear that some well-intended attempts to appreciate diversity could inadvertently contribute to the very insensitivity they were intended to prevent. It is my view that group influences are extremely important in shaping individual identity, but the effect of culture on a given individual cannot be verified without consulting that person directly. (PsycINFO Database Record (c) 2010 APA, all rights reserved)