In this study, the polymer/MWCNT nanocomposites were synthesized from the pristine MWCNT and polymer binders using functionalization with solution processing methods. The synthesized polymer/MWCNT nanocomposites exhibited high specific surface areas than the pristine MWCNT. The MWCNT/Nafion nanocomposite attributed to the maximum peak current at 5.795 × 10?5 (A) while the peak current of MWCNT/PBI was obtained at 3.662 × 10?5 (A). Moreover, polymer/MWCNT based electrocatalysts performed better electrochemical activity because of polymers binders can assist electrochemical interaction using the high surface areas of the catalyst supporting material. Also, the MEAs fabricated using the hot pressing method, while the acid doped PBI membrane sandwiched between the electrodes. The fabricated MEAs were successfully demonstrated in a single cell and found capable of measuring a maximum power density of 112.10 mW/cm2 under 150 °C temperature. In conclusion, the synthesized catalyst-supporting materials enhanced the electrochemical activity and catalyst stability which fulfilling the main objective of this study. 相似文献
The genetic expression of chimeric antigen receptors (CARs) on the surfaces of T cells enables the redirection of T cell specificity. To enhance the versatility of T cells as tumor-specific killers, we developed a nongenetic approach by which azide-containing sialic acids were metabolically incorporated into T cells to modify cellular sialyl glycans. After successful display of these moieties on the T cells, small-molecule ligands such as RGD and folate (as proof-of-concept, rather than supersized antibodies) were clicked orthogonally, leading to highly selective time- and dose-dependent cytotoxicity to integrin αvβ3- and folate-receptor-positive cells, respectively. This chemical approach provides a facile platform for rational design of tumor-specific cytotoxic T cells for targeted immunotherapy. 相似文献
Composite biomaterials are in high demand in the medical field of today. The combination of bioactive wollastonite (WA) glass ceramic with the biocompatibility of alloy titanium (Ti6Al4V) could be a good candidate for implant applications. The rheological properties of Ti6Al4V/WA feedstock show a pseudoplastic behaviour with low activation energy. The feedstock was successfully injected as a green part with no defects. The green part was solvent debound for 6?h in heptane and thermal debound in an argon environment for 1?h. The brown part was successfully sintered at 1300?°C for 3?h with 5?°C/min heating and cooling rates. The average sintered density was 4.12?g/cm3; which is 97.5% from the theoretical density. The highest Young's modulus obtained was 18.10?GPa; which is in the range of human bone strength. EDX analysis shows that by increasing sintering temperature, the level of oxygen decreased. Cell viability test shown an absorbance increased with days increasing indicated that the cellular were proliferated on the composite Ti6Al4V/WA composite which also proved that the composite was non-toxic. This indicates that the Ti6Al4V/WA composite is suitable for bone implant applications. 相似文献
Since powerful editing software is easily accessible, manipulation on images is expedient and easy without leaving any noticeable evidences. Hence, it turns out to be a challenging chore to authenticate the genuineness of images as it is impossible for human’s naked eye to distinguish between the tampered image and actual image. Among the most common methods extensively used to copy and paste regions within the same image in tampering image is the copy-move method. Discrete Cosine Transform (DCT) has the ability to detect tampered regions accurately. Nevertheless, in terms of precision (FP) and recall (FN), the block size of overlapping block influenced the performance. In this paper, the researchers implemented the copy-move image forgery detection using DCT coefficient. Firstly, by using the standard image conversion technique, RGB image is transformed into grayscale image. Consequently, grayscale image is segregated into overlying blocks of m × m pixels, m = 4.8. 2D DCT coefficients are calculated and reposition into a feature vector using zig-zag scanning in every block. Eventually, lexicographic sort is used to sort the feature vectors. Finally, the duplicated block is located by the Euclidean Distance. In order to gauge the performance of the copy-move detection techniques with various block sizes with respect to accuracy and storage, threshold D_similar = 0.1 and distance threshold (N)_d = 100 are used to implement the 10 input images in order. Consequently, 4 × 4 overlying block size had high false positive thus decreased the accuracy of forged detection in terms of accuracy. However, 8 × 8 overlying block accomplished more accurately for forged detection in terms of precision and recall as compared to 4 × 4 overlying block. In a nutshell, the result of the accuracy performance of different overlying block size are influenced by the diverse size of forged area, distance between two forged areas and threshold value used for the research.