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31.
Double emulsion‐encapsulated guggul exhibits improved in vivo hypocholesterolaemic action in rats
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Heena Lamba Latha Sabikhi Dipesh Aggarwal Urmila Choudhary Srinu Reddi Suman Kapila Rajeev Kapila 《International Journal of Food Science & Technology》2018,53(3):626-633
Guggul tree or Commiphora mukul is a small thorny herb having remarkable hypocholesterolaemic properties. Its therapeutic effects are because of its biocomponent guggulsterones, especially guggulsterone E and Z. In this research, double emulsion‐based spread was tried to improve the bioavailability of the herb guggul in in vivo rat model. The effect of the different diets with encapsulated and nonencapsulated guggul was evaluated and compared after 6 weeks, based on the final body weight and analysis of organs, serum and faeces of normal and hypercholesterolaemic (H) rats. It was evident from the results that double emulsion‐encapsulated guggul showed better control on weight of H rats (25.98% lower), inhibition of HMG CoA reductase (3.95 times less) activity and reduction in atherosclerotic index (47.2%), as compared to diet with unencapsulated guggul. Encapsulation of guggul also improved faecal excretion of bile acids, lipids and total cholesterol in H and normal rats. 相似文献
32.
Suman Lata Sandeep Yadav Rachna Bhardwaj C. S. Pundir 《Sensing and Instrumentation for Food Quality and Safety》2011,5(3-4):104-110
A method is described for construction of an amperometric biosensor for specific determination of tyramine, using black gram tyramine oxidase immobilized covalently on an epoxy resin membrane. The biosensor had optimum response within 10 s at pH 8.5 and 35 °C. A linear relationship was observed between tyramine concentrations and current (mA) in the range of 0.24 to 3.47 mg/dL. The biosensor was employed for determination of tyramine in beer and sauce. The detection limit of sensor was 0.24 mg/dL. The mean analytical recovery of added tyramine (0.5 and 1.0 mg/dL) was 97.3 ± 2.3 and 95.9 ± 3.4%. Within and between batch coefficient of variation were 5.1 and 5.34%, respectively. Enzyme electrode showed 35% loss in its initial activity after its regular use over a period of 2 months. The biosensor has the advantage that it does not suffer from leaching of enzyme and measures tyramine specifically. 相似文献
33.
Ramya Iyer S.K. Tomar Suman Kapila Jiju Mani Rameshwar Singh 《Food research international (Ottawa, Ont.)》2010,43(1):103-110
This study aimed at assessing the probiotic potential of two high folate producing Streptococcus thermophilus strains (RD102 and RD104) isolated from Indian fermented milk products by both in vitro and in vivo tests. These strains were able to survive at pH 2.5 and 2% bile with a good bile salt hydrolase activity, cell surface hydrophobicity and sensitivity to most of the clinically important antibiotics. On evaluation for gastrointestinal transit tolerance these showed a viable count of 5 log cfu mL?1 and 7 log cfu mL?1, respectively in simulated gastrointestinal juice of pH 2.0 and 2% bile. During the in vivo feeding trial in mice the strains showed a viable count of about 7 log cfu g?1 faeces and 6 log cfu g?1 of large intestine, respectively. These strains were hence observed to possess favorable strain specific probiotic properties and have the potential to be a source of novel probiotics. 相似文献
34.
Suman Rani Neetu Ahlawat R. Punia Kanta Maan Sangwan Sunita Rani 《Ceramics International》2018,44(6):5996-6001
In this work, Sr and Zn co-doped calcium copper titanate having nominal formula Ca0.90Sr0.10Cu3Ti3.95Zn0.05O12 has been synthesized and systematically studied for structure, dielectric and electrical properties. The phase purity of the prepared composition has been confirmed by X-ray diffraction (XRD) pattern and various structural parameters are presented here with Rietveld refinement data. The Scanning electron microscopy (SEM) image revealed the presence of homogeneous fine-grained microstructure investigated in the prepared ceramic. The impedance data well fitted with 2 R-CPE model confirmed the non-ideality of the system. Dielectric studies have shown the existence of two relaxation processes in low and high frequency domains. Low frequency dielectric response proposed as a combination of Maxwell-Wagner relaxation and intrinsic defect (Vo++) while high frequency behavior has been interpreted in terms of polaronic relaxation caused by hopping process of an electron between Ti3+ and Ti4+ states. The frequency dependent behavior of conductivity has been well fitted to Dong’s model and interpreted in term of Overlapping Large Polaron Tunneling (OLPT) mechanism. The various parameters; relaxation angular frequency (ω1) of Debye process, ionic hopping frequency (ω2), dc conductivity (σo), cole- cole parameter (α) and frequency exponent (s) have been determined by Dong’s Model fitting. 相似文献
35.
In this work we present a methodology for intelligent path planning in an uncertain environment using vision-like sensors, i.e., sensors that allow the sensing of the environment non-locally. Examples would include a mobile robot exploring an unknown terrain or a micro-UAV navigating in a cluttered urban environment. We show that the problem of path planning in an uncertain environment, under certain assumptions, can be posed as the adaptive optimal control of an uncertain Markov decision process, characterized by a known, control-dependent system, and an unknown, control-independent environment. The strategy for path planning then reduces to computing the control policy based on the current estimate of the environment, also known as the “certainty-equivalence” principle in the adaptive control literature. Our methodology allows the inclusion of vision-like sensors into the problem formulation, which, as empirical evidence suggests, accelerates the convergence of the planning algorithms. Further we show that the path planning and estimation problems, as formulated in this paper, possess special structure which can be exploited to significantly reduce the computational burden of the associated algorithms. We apply this methodology to the problem of path planning of a mobile rover in a completely unknown terrain. 相似文献
36.
The powder sample of Cr1.8Ti0.2O3 (CTO) was obtained by a sol–gel method. The thick films were developed on identical ceramic tubes of 4 mm length comprising of two Au-electrodes and printing an eight-layer film prepared by mixing CTO with glass powder and -terpinol as an organic vehicle. X-ray powder diffraction (XRD) patterns showed the formation of a single phase. The scanning electron microscope (SEM) images of the ceramic sensor treated at 850 °C revealed that the grain size was larger than 400 nm for the individual isolated grains on the surface, and the agglomerated dense spheroidal platelets had the size of 1–4 μm in diameter. The AC impedance measurement in ambient air showed that the resistance decreased nearly by two orders of magnitude with an increase in temperature in the range of 400–600 °C for both the powder sample and the thick film, and the activation energy Ea derived from the measurement was found to be 0.35 and 0.36 eV for the powder and the film, respectively. The films were exposed to various concentrations of alcohols (0.4–1.2 ppm of methanol and 1.0–5.0 ppm of ethanol), followed by determination of sensor response, sensitivity and reversibility and reproducibility. The origin of the gas response was attributed to the surface reaction of R-OH (R = methyl and ethyl group) with O−(ads) to form adsorbed R-CHO, which was desorbed as a gas at 400 °C after the sensor departing from the gas. 相似文献
37.
M. Suman 《应用聚合物科学杂志》2007,106(3):1622-1625
A comprehension of the phenomenon that controls the diffusion of an organic solvent to the pores of a polymeric matrix is fundamental for optimizing the operating conditions to distribute a homogeneous catalyst, which has to be supported on it. The traditional sessile drop method is impossible to use when a high polymer‐solvent affinity exists. In this case, a different determination technique, similar to the Wilhelmy static mode method and based on the direct observation of the capillary raising curve of the solvent on the polymeric surface, has been set together with an experimental apparatus specifically built to perform measurements at a desired temperature and atmosphere. Such a technique has been demonstrated to be easy and promising for differentiating the behavior of different polyolefins [polypropylene (PP), high density polyethylene (HDPE), heterophasic copolymers (COPO)] at equal solvent and different temperatures. © 2007 Wiley Periodicals, Inc. J Appl Polym Sci, 2007 相似文献
38.
Alumina-supported MoO3 was found to be an efficient heterogeneous and recyclable catalyst for the oxidation of tertiary nitrogen compounds to N-oxides
in excellent yields using anhydrous t-BuOOH as oxidant under mild reaction conditions. 相似文献
39.
An improved method for the synthesis of 3,4-dihydropyrimidinones by one pot cyclocondensation of aldehyde, β-dicarbonyl compound
and urea with significant enhancement in reaction rates using room temperature ionic liquid [bmim] BF4 immobilized Cu(acac)2 as recyclable catalytic system is described. 相似文献
40.
Suman Roy Janardan Misra Indranil Saha 《Software Testing, Verification and Reliability》2016,26(8):548-571
We revisit the problem of real‐time verification with dense‐time dynamics using timeout and calendar‐based models and simplify this to a finite state verification problem. We introduce a specification formalism for these models and capture their behaviour in terms of semantics of timed transition systems. We discuss a technique, which reduces the problem of verification of qualitative temporal properties on infinite state space of a large fragment of these timeout and calender‐based transition systems into that on clock‐less finite state models through a two‐step process comprising of digitization and finitary reduction. This technique enables us to verify safety invariants for real‐time systems using finite state model checking avoiding the complexity of infinite state (bounded) model checking and scale up models without applying techniques from induction‐based proof methodology. In the same manner, we verify timeliness properties. Moreover, we can verify liveness for real‐time systems, which are not possible by using induction with infinite state model checkers. Copyright © 2016 John Wiley & Sons, Ltd. 相似文献