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31.
Huiquan Wu Mansoor A. Khan Ajaz S. Hussain - Current address: Global Biopharmaceutical Development Sandoz Princeton New Jersey. 《Chemical Engineering Communications》2007,194(6):760-779
FDA's Process Analytical Technology (PAT) initiative provides an unprecedented opportunity for chemical engineers to play significant roles in the pharmaceutical industry. In this article, the authors provide their perspectives on (1) the need for chemical engineering principles in pharmaceutical development for a thorough process understanding; (2) applications of chemical engineering principles to meet the challenges from the semiconductor and pharmaceutical industries; and (3) the integration of chemical engineering practice into the semiconductor and pharmaceutical industries to achieve process understanding and the desired state of quality-by-design. A real-world case study from the semiconductor industry is presented to demonstrate how a classic chemical engineering concept, mixing homogeneity, can be implemented by inducing forced flow to ensure an excellent copper electrochemical plating process performance and to improve product quality substantially. Further, a case study of brake system design is discussed with the concept of Dr. Taguchi's robust engineering design to illustrate how quality-by-design can be achieved through appropriate experimental design, in conjunction with the discussion on the concept of quality-by-design in pharmaceuticals. Third, a case study of freeze-dried sodium ethacrynate is presented to demonstrate the vital importance of controlling the processing factors to achieve the desired product stability. Finally, the problems of the current pharmaceutical manufacturing mode, the opportunities and engineering challenges during implementation of PAT in the pharmaceutical industry, and the role of chemical engineering in implementation of PAT is discussed in detail. 相似文献
32.
T.A. Owoseni A. Rincon Romero Z. Pala F. Venturi E.H. Lester D.M. Grant T. Hussain 《Ceramics International》2021,47(17):23803-23813
Yttrium aluminium garnet (YAG) is a promising topcoat material for thermal barrier coatings due to its high temperature stability and better CMAS (calcium-magnesium-alumino-silicate) resistance. YAG topcoats were deposited by suspension and solution precursor high-velocity oxy-fuel (HVOF) thermal spray. The relationships between processing, microstructure and final properties were studied through a range of characterization techniques and thermal cycling tests. The microstructure of the as-sprayed YAG topcoat from stoichiometric solution precursor (SP-YAG) had distributed pores and inter-splat boundaries, while the as-sprayed topcoat produced from suspension (S-YAG) had vertical and branched micro cracks, pores, and inter-splat boundaries. Both as-sprayed coatings were composed of amorphous phase, hexagonal yttrium aluminium perovskite (YAP) and cubic YAG. In thermal cycling tests, 20% of SP-YAG failure was reached after the 10th cycle; whereas, S-YAG reached the failure criteria between the 60th and 70th cycle. The failure of both the SP-YAG and the S-YAG topcoats occurred due to thermal stresses during the thermal cycling. 相似文献
33.
Zara Hamid Faisal Bashir Hussain Jae-Young Pyun 《Multimedia Tools and Applications》2016,75(14):8195-8216
Wireless Multimedia Sensor Networks (WMSNs) consist of networks of interconnected devices involved in retrieving multimedia content, such as, video, audio, acoustic, and scalar data, from the environment. The goal of these networks is optimized delivery of multimedia content based on quality of service (QoS) parameters, such as delay, jitter and distortion. In multimedia communications each packet has strict playout deadlines, thus late arriving packets and lost packets are treated equally. It is a challenging task to guarantee soft delay deadlines along with energy minimization, in resource constrained, high data rate WMSNs. Conventional layered approach does not provide optimal solution for guaranteeing soft delay deadlines due to the large amount of overhead involved at each layer. Cross layer approach is fast gaining popularity, due to its ability to exploit the interdependence between different layers, to guarantee QoS constraints like latency, distortion, reliability, throughput and error rate. The paper presents a channel utilization and delay aware routing (CUDAR) protocol for WMSNs. This protocol is based on a cross-layer approach, which provides soft end-to-end delay guarantees along with efficient utilization of resources. Extensive simulation analysis of CUDAR shows that it provides better delay guarantees than existing protocols and consequently reduces jitter and distortion in WMSN communication. 相似文献
34.
35.
Prior approaches (e.g., off-axis holography) to overcoming the limitations of in-line holography for particle fields, namely, intrinsic speckle noise and depth resolution, involved an increased complexity of the optical system. The in-line recording and off-axis viewing (IROV) technique employs a single laser beam to record an in-line hologram, which is then viewed off axis during reconstruction. The signal-to-noise ratio and depth resolution of IROV are higher than conventional in-line holography by an order of magnitude and are comparable with off-axis holography. IROV is a much simpler approach than off-axis holography and is highly promising for holographic particle velocimetry. Measurements of the three dimensional flow velocity field of a vortex ring obtained by an IROV-based holographic particle velocimetry system are presented. 相似文献
36.
Effective participation of wind turbines in frequency control of a two-area power system using coot optimization 下载免费PDF全文
In this paper, load frequency control is performed for a two-area power system incorporating a high penetration of renewable energy sources. A droop controller for a type 3 wind turbine is used to extract the stored kinetic energy from the rotating masses during sudden load disturbances. An auxiliary storage controller is applied to achieve effective frequency response. The coot optimization algorithm (COA) is applied to allocate the optimum parameters of the fractional-order proportional integral derivative (FOPID), droop and auxiliary storage controllers. The fitness function is represented by the summation of integral square deviations in tie line power, and Areas 1 and 2 frequency errors. The robustness of the COA is proven by comparing the results with benchmarked optimizers including: atomic orbital search, honey badger algorithm, water cycle algorithm and particle swarm optimization. Performance assessment is confirmed in the following four scenarios: (i) optimization while including PID controllers; (ii) optimization while including FOPID controllers; (iii) validation of COA results under various load disturbances; and (iv) validation of the proposed controllers under varying weather conditions. 相似文献
37.
Data-driven next-generation smart grid towards sustainable energy evolution: techniques and technology review 下载免费PDF全文
Faiaz Ahsan Nazia Hasan Dan Subrata K. Sarker Li Li S. M. Muyeen Md. Firoj Ali Zinat Tasneem Md. Mehedi Hasan Sarafat Hussain Abhi Md. Robiul Islam Md. Hafz Ahame Md. Manirul Islam Sajal K. Das Md. Faisal R. Badal Prangon Das 《电力系统保护与控制》2023,8(3):696-737
Meteorological changes urge engineering communities to look for sustainable and clean energy technologies to keep the environment safe by reducing CO2 emissions. The structure of these technologies relies on the deep integration of advanced data-driven techniques which can ensure efcient energy generation, transmission, and distribution. After conducting thorough research for more than a decade, the concept of the smart grid (SG) has emerged, and its practice around the world paves the ways for efcient use of reliable energy technology. However, many developing features evoke keen interest and their improvements can be regarded as the next-generation smart grid (NGSG). Also, to deal with the non-linearity and uncertainty, the emergence of data-driven NGSG technology can
become a great initiative to reduce the diverse impact of non-linearity. This paper exhibits the conceptual framework of NGSG by enabling some intelligent technical features to ensure its reliable operation, including intelligent control, agent-based energy conversion, edge computing for energy management, internet of things (IoT) enabled inverter, agent-oriented demand side management, etc. Also, a study on the development of data-driven NGSG is discussed to facilitate the use of emerging data-driven techniques (DDTs) for the sustainable operation of the SG. The prospects of DDTs in the NGSG and their adaptation challenges in real-time are also explored in this paper from various points of view including engineering, technology, et al. Finally, the trends of DDTs towards securing sustainable and clean energy evolution from the NGSG technology in order to keep the environment safe is also studied, while some major future issues are highlighted. This paper can ofer extended support for engineers and researchers in the context of data-driven technology and the SG. 相似文献
38.
Muhammad Ahsan Razaq Muhammad Rehan Muntazir Hussain Shakeel Ahmed Keum-Shik Hong 《Asian journal of control》2023,25(5):4096-4112
This paper investigates a local observer-based leader-following consensus control of one-sided Lipschitz (OSL) multi-agent systems (MASs) under input saturation. The proposed consensus control scheme has been formulated by using the OSL property, input saturation, directed graphs, estimated states, and quadratic inner-boundedness condition by attaining the regional stability. It is assumed that the graph always includes a (directed) spanning tree with respect to the leader root to develop matrix inequalities for investigating parameters of the proposed observer and consensus protocols. Further, a new observer-based consensus tracking method for MASs with saturation, concerning independent topologies for communicating outputs and estimates over the network, is explored to deal with a more perplexing and realistic situation. In contrast to the traditional methods, the proposed consensus approach considers output feedback and deals with the input saturation for a generalized class of nonlinear systems. The efficiency of the obtained results is illustrated via application to a group of five moving agents in the Cartesian coordinates. 相似文献
39.
Wireless Personal Communications - Multimodal biometric systems combine feature knowledge from multiple traits to overcome shortcomings of unimodal systems. However, most of the traditional... 相似文献
40.
Hussain Naziya Maheshwary Priti Shukla Piyush Kumar Singh Anoop 《Wireless Personal Communications》2022,126(4):2841-2868
Wireless Personal Communications - A Greedy Perimeter Coordinator Routing and Mobility Awareness (GPCR-MA) vehicular routing is a widely accepted routing protocol for VANET (Vehicular Ad hoc... 相似文献