High-cycle fatigue characterization of titanium 5Al-2.5Sn alloy

High-cycle fatigue behaviour of titanium 5Al-2.5Sn alloy at room temperature has been studied. S-N curve characterization is performed at different stress ratios ranging from 0 to 0.9 on a subsized fatigue specimen. Both two-stress and three-stress level tests are conducted at different stress ratios to study the cumulative fatigue damage. Life prediction techniques of linear damage rule, double linear damage rule and damage curve approaches are applied, and results are compared with the experimental data. The agreement between prediction and experiment is found to be excellent.     

Acquired autoimmune thrombocytopenia post-bone marrow transplantation for severe combined immunodeficiency

Children with severe combined immunodeficiency (SCID) have profoundly diminished humoral and cellular immunity resulting in death during infancy unless immune reconstitution occurs by bone marrow transplantation (BMT). Thrombocytopenia post-bone marrow transplantation can be seen in relation to infection, graft-versus-host disease (GVHD) and rarely, as an autoimmune phenomenon due to immune dysregulation. We report two cases of severe AITP following BMT for SCID. Both cases developed large intracerebral hemorrhages from which one died. Autoimmune thrombocytopenia in this setting can be life-threatening and we recommend early and active intervention.     

Nonparametric change detection and estimation in large-scale sensor networks

The problem of detecting changes in the distribution of alarmed sensors is considered. Under a nonparametric change detection framework, several detection and estimation algorithms are presented based on the Vapnik-Chervonenkis (VC) theory. Theoretical performance guarantees are obtained by providing error exponents for false-alarm and miss detection probabilities. Recursive algorithms for the efficient computation of test statistics are derived. The estimation problem is also considered in which, after detection is made, the location with maximum distribution change is estimated.     

OPNET环境下的PIM—SM组播路由协议仿真

IPv6组播技术作为下一代互联网的核心技术之一,相对于IPv4组播技术具有更大的优越性。文章首先对PIM-SM组播协议在IPv6上实现PIM-SM涉及的问题进行了论述,然后在OPNET网络仿真模型中实现了对IPv6和IPv4混合网络场景的配置,进行组播的仿真实验比较单播与组播网络的性能,系统地分析了PIM-SM协议在OPNET中的实现。     

基于健康档案的医疗系统PKI信任模型研究

随着医疗信息技术的高速发展,我国医疗信息化建设中的信息安全问题显得越来越重要。而基于电子健康档案的医疗系统中身份认证管理已成为解决医疗信息系统中的安全问题中关键的一环。文章以基于电子健康档案的医疗系统中身份认证机制为出发点,分析PKI中各种信任模型的特点,对现有的方式进行研究和分析,设计出符合适合区域医疗信息平台的PKI信任模型,从而使基于电子健康档案的医疗系统中的身份认证机制更为安全、高效。希望给后续研究这一课题的研究者提供参考。     

MPEG-2／4AAC音频编码模块的验证

先进音频编码（AdvancedAudioCoding,AAC）以其多声道、多采样率、高压缩比、音质好等特点被广泛使用。文中首先介绍了MPEG-2／4AAC音频编码技术;接着基于MPEG-2／4AAC音频编码原理,开发了时钟复位、寄存器配置和音频数据收发的BFM模型,搭建了音频编码模块的RTL级虚拟验证平台,同时归纳了验证项;最后基于此验证平台和验证项,对设计进行了全面的仿真验证。实践证明该验证方法效率高、收敛快、覆盖率高,取得了较好的效果,为后续的FPGA平台验证和芯片应用提供了有力的保证。     

Optimizing nonlinearity of piezoresistive pressure sensors by an asymmetric Wheatstone bridge

Microsystem Technologies - Since nonlinearity is critical to silicon piezoresistive pressure sensors, this paper combined theoretical analysis and simulation to study the effect of changing the...     

First order sensitivity analysis of flexible multibody systems using absolute nodal coordinate formulation

Design sensitivity analysis of flexible multibody systems is important in optimizing the performance of mechanical systems. The choice of coordinates to describe the motion of multibody systems has a great influence on the efficiency and accuracy of both the dynamic and sensitivity analysis. In the flexible multibody system dynamics, both the floating frame of reference formulation (FFRF) and absolute nodal coordinate formulation (ANCF) are frequently utilized to describe flexibility, however, only the former has been used in design sensitivity analysis. In this article, ANCF, which has been recently developed and focuses on modeling of beams and plates in large deformation problems, is extended into design sensitivity analysis of flexible multibody systems. The Motion equations of a constrained flexible multibody system are expressed as a set of index-3 differential algebraic equations (DAEs), in which the element elastic forces are defined using nonlinear strain-displacement relations. Both the direct differentiation method and adjoint variable method are performed to do sensitivity analysis and the related dynamic and sensitivity equations are integrated with HHT-I3 algorithm. In this paper, a new method to deduce system sensitivity equations is proposed. With this approach, the system sensitivity equations are constructed by assembling the element sensitivity equations with the help of invariant matrices, which results in the advantage that the complex symbolic differentiation of the dynamic equations is avoided when the flexible multibody system model is changed. Besides that, the dynamic and sensitivity equations formed with the proposed method can be efficiently integrated using HHT-I3 method, which makes the efficiency of the direct differentiation method comparable to that of the adjoint variable method when the number of design variables is not extremely large. All these improvements greatly enhance the application value of the direct differentiation method in the engineering optimization of the ANCF-based flexible multibody systems.