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排序方式: 共有3576条查询结果,搜索用时 15 毫秒
71.
Michael B. Jacobs 《Natural Gas \u0026amp; Electricity》2016,33(5):1-6
Most of the discussion of the adoption of high levels of renewable energy in the electricity sector has focused on the adaptations and flexibility of the electricity power system. When these studies are made with assumptions about flexible natural gas generation, there is rarely a mention of the impacts on gas pipeline operations. The gas industry—in particular, the pipeline operators—has an opportunity to adapt to changes in the electric power system by recognizing and meeting the growing need for operational flexibility. 相似文献
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P. Hijma R. V. van Nieuwpoort C. J. H. Jacobs H. E. Bal 《Concurrency and Computation》2015,27(17):4515-4554
Many‐core hardware is targeted specifically at obtaining high performance, but reaching high performance is often challenging because hardware‐specific details have to be taken into account. Although there are many programming systems that try to alleviate many‐core programming, some providing a high‐level language, others providing a low‐level language for control, none of these systems have a clear and systematic methodology as a foundation. In this article, we propose stepwise‐refinement for performance: a novel, clear, and structured methodology for obtaining high performance on many‐cores. We present a system that supports this methodology, offers multiple levels of abstraction to provide programmers a trade‐off between high‐level and low‐level programming, and provides programmers detailed performance feedback. We evaluate our methodology with several widely varying compute kernels on two different many‐core architectures: a Graphical Processing Unit (GPU) and the Xeon Phi. We show that our methodology gives insight in the performance, and that in almost all cases, we gain a substantial performance improvement using our methodology. Copyright © 2015 John Wiley & Sons, Ltd. 相似文献
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Mitochondrial uncoupling protein 1 (UCP1) is the crucial mechanistic component of heat production in classical brown fat and the newly identified beige or brite fat. Thermogenesis inevitably comes at a high energetic cost and brown fat, ultimately, is an energy-wasting organ. A constrained strategy that minimizes brown fat activity unless obligate will have been favored during natural selection to safeguard metabolic thriftiness. Accordingly, UCP1 is constitutively inhibited and is inherently not leaky without activation. It follows that increasing brown adipocyte number or UCP1 abundance genetically or pharmacologically does not lead to an automatic increase in thermogenesis or subsequent metabolic consequences in the absence of a plausible route of concomitant activation. Despite its apparent obviousness, this tenet is frequently ignored. Consequently, incorrect conclusions are often drawn from increased BAT or brite/beige depot mass, e.g., predicting or causally linking beneficial metabolic effects. Here, we highlight the inherently inactive nature of UCP1, with a particular emphasis on the molecular brakes and releases of UCP1 activation under physiological conditions. These controls of UCP1 activity represent potential targets of therapeutic interventions to unlock constraints and efficiently harness the energy-expending potential of brown fat to prevent and treat obesity and associated metabolic disorders. 相似文献
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Paul W. Francisco Stacy Gloss Jonathan Wilson William Rose Yigang Sun Sherry L. Dixon Jill Breysse Ellen Tohn David E. Jacobs 《Indoor air》2020,30(1):147-155
Energy retrofits can reduce air exchange, raising the concern of whether indoor radon and moisture levels could increase. This pre/post-intervention study explored whether simple radon interventions implemented in conjunction with energy retrofits can prevent increases in radon and moisture levels. Treatment homes (n = 98) were matched with control (no energy retrofits or radon intervention) homes (n = 12). Control homes were matched by geographic location and foundation type. t-tests were used to determine whether post-energy retrofit radon and moisture level changes in treatment homes significantly differed from those in control homes. The radon interventions succeeded in preventing statistically significant increases in first floor radon using arithmetic (p = 0.749) and geometric means (p = 0.120). In basements, arithmetic (p = 0.060) and geometric (p = 0.092) mean radon levels statistically significantly increased, consistent with previous studies which found that basement radon levels may increase even if first floor levels remain unchanged. Changes in infiltration were related to changes in radon (p = 0.057 in basements; p = 0.066 on first floors). Only 58% of the change in infiltration was due to air sealing, with the rest due to weather changes. There was no statistically significant association between air sealing itself and radon levels on the first floor (p = 0.664). Moisture levels also did not significantly increase. 相似文献
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Sparrman T Oquist M Klemedtsson L Schleucher J Nilsson M 《Environmental science & technology》2004,38(20):5420-5425
To understand wintertime controls of biogeochemical processes in high latitude soils it is essential to distinguish between direct temperature effects and the effects of changes in water availability mediated by freezing. Efforts to separate these controls are hampered by a lack of adequate methods to determine the proportion of unfrozen water. In this study we present a high-field 2H2O NMR method for quantifying unfrozen water content in frozen soil. The experimental material consisted of the humic layer of a boreal spruce forest soil mixed with varying proportions of quartz sand and humidified with deuterium-enriched water. The relative standard deviation of unfrozen water content (measured as NMR signal integral) was less than 2% for repeated measurements on a given sample and 3.5% among all samples, based on a total of 16 measurements. As compared to 1H NMR, this 2H NMR method was found to be superior for several reasons: it is less sensitive to field inhomogeneity and paramagnetic impurities, it gives a bigger line shape difference between the ice and liquid signal, it shows a sharper response to water fusion, and it excludes the possibility of hydrogen in the organic material interfering with the measurement. 相似文献
80.