Development and evaluation of a palm-sized optical PM2.5 sensor

A new palm-sized optical PM_2.5 sensor has been developed and its performance evaluated. The PM_2.5 mass concentration was calculated from the distribution of light scattering intensity by considering the relationship between scattering intensity and particle size. The results of laboratory tests suggested that the sensor can detect particles with diameters as small as ～0.3 µm and can measure PM_2.5mass concentrations as high as ～600 µg/m³. Year-round ambient observations were conducted at four urban and suburban sites in Fukuoka, Kadoma, Kasugai, and Tokyo, Japan. Daily averaged PM_2.5 mass concentration data from our sensors were in good agreement with corresponding data from the collocated standard instrument at the Kadoma site, with slopes of 1.07–1.16 and correlation coefficients (R) of 0.90–0.91, and with those of the nearest observatories of the Ministry of the Environment of Japan, at 1.7–4.1 km away from our observation sites, with slopes of 0.97–1.23 and R of 0.89–0.95. Slightly greater slopes were observed in winter than in summer, except at Tokyo, which was possibly due to the photochemical formation of relatively small secondary particles. Under high relative humidity conditions (>70%), the sensor has a tendency to overestimate the PM_2.5 mass concentrations compared to those measured by the standard instruments, except at Fukuoka, which is probably due to the hygroscopic growth of particles. This study demonstrates that the sensor can provide reasonable PM_2.5 mass concentration data in urban and suburban environments and is applicable to studies on the environmental and health effects of PM_2.5.

Copyright © 2018 American Association for Aerosol Research     

Cellular Antisense Activity of PNA–Oligo(bicycloguanidinium) Conjugates Forming Self‐Assembled Nanoaggregates

A series of peptide nucleic acid–oligo(bicycloguanidinium) (PNA–BG_n) conjugates were synthesized and characterized in terms of cellular antisense activity by using the pLuc750HeLa cell splice correction assay. PNA–BG₄ conjugates exhibited low micromolar antisense activity, and their cellular activity required the presence of a hydrophobic silyl terminal protecting group on the oligo(BG) ligand and a minimum of four guanidinium units. Surprisingly, a nonlinear dose–response with an activity threshold around 3–4 μM , indicative of large cooperativity, was observed. Supported by light scattering and electron microscopy analyses, we propose that the activity, and thus cellular delivery, of these lipo‐PNA–BG₄ conjugates is dependent on self‐assembled nanoaggregates. Finally, cellular activity was enhanced by the presence of serum. Therefore we conclude that the lipo‐BG‐PNA conjugates exhibit an unexpected mechanism for cell delivery and are of interest for further in vivo studies.     

Homogeneous Tritylation of Cellulose in A Sulfur Dioxide – Diethylamine – Dimethyl Sulfoxide Medium

The present investigation was undertaken to see if a practical method could be developed for homogeneous tritylation of cellulose in a non-aqueous solvent of cellulose. Our new procedure of tritylation of cellulose can easily be carried out under homogeneous conditions by dissolving cellulose in a sulfur dioxide(SO₂)-diethylamine (DEA)-dimethyl sulfoxide(DMSO) solvent system, one or the non-aqueous cellulose solvents, followed by addition of trityl chloride and pyridine. This new method can avoid the time consuming pretreatment for the decrystallization of cellulose which has been necessary in the traditional procedure and can lower the reaction temperature. IR spectra of the products indicated the formation of trityl cellulose. Measurements of dielectric properties of the products confirmed that trityl groups were selectively introduced at the primary hydroxyl groups in cellulose. This conclusion was also confirmed by a H-NMR study in which the tritylated products was first acetylated, detritylated and then trideuterioacetylated and H-NMR spectra were taken at each stage and examined comparatively.     

Characterization and application of polypropylene films modified with stimuli‐sensitive copolymers with an Ar‐plasma postpolymerization technique

Surface‐modified polypropylene (PP) films with thermally and photochemically sensitive copolymers consisting of N‐(2‐hydroxypropyl)methacrylamide (HPMA) and 4‐(4‐methoxyphenylazo)phenyl methacrylate (MPAP), poly(HPMA‐co‐MPAP)‐g‐PP (abbreviated g‐PP) film, were prepared by graft copolymerization with an Ar‐plasma postpolymerization technique. The surfaces of the g‐PP films were characterized by means of X‐ray photoelectron spectroscopy; the percentage grafting of poly(HPMA‐co‐MPAP) with a number‐average molecular weight of 3.28 × 10⁴ was 7.12%, and the molar ratio of HPMA–MPAH in the copolymer was 0.75:0.25. The stimuli‐sensitive adsorption of albumin and polystyrene microspheres on the g‐PP film was also measured. © 2003 Wiley Periodicals, Inc. J Appl Polym Sci 90: 143–148, 2003     

Burning Characteristics of Ammonium Nitrate‐Based Composite Propellants Supplemented with Fe2O3

Ammonium nitrate (AN)‐based composite propellants have attracted a considerable amount of attention because of the clean burning nature of AN as an oxidizer. However, such propellants have several disadvantages such as poor ignition and a low burning rate. In this study, the burning characteristics of AN‐based propellants supplemented with Fe₂O₃ as a burning catalyst were investigated. The addition of Fe₂O₃ is known to improve the ignitability at low pressure. Fe₂O₃ addition also increases the burning rate, while the pressure exponent generally decreases. The increasing ratio (R) of the burning rate of the AN/Fe₂O₃ propellant to that of the corresponding AN propellant vs. the amount of Fe₂O₃ added (ξ) depends on the burning pressure and AN content. R decreases at threshold value of ξ. The most effective value of ξ for increasing the burning rate was found to be 4 % for the propellant at 80 % AN, and the value generally decreased with decreasing AN content. According to thermal decomposition kinetics, Fe₂O₃ accelerates the reactions of AN and binder decomposition gases in the condensed‐ and/or gas‐phase reaction zones. The burning characteristics of the AN‐based propellant were improved by combining catalysts with differing catalytic mechanisms instead of supplementing the propellant with a single catalyst owing to the multiplicative effect of the former.     

The Functions of Metallothionein and ZIP and ZnT Transporters: An Overview and Perspective

Around 3000 proteins are thought to bind zinc in vivo, which corresponds to ~10% of the human proteome. Zinc plays a pivotal role as a structural, catalytic, and signaling component that functions in numerous physiological processes. It is more widely used as a structural element in proteins than any other transition metal ion, is a catalytic component of many enzymes, and acts as a cellular signaling mediator. Thus, it is expected that zinc metabolism and homeostasis have sophisticated regulation, and elucidating the underlying molecular basis of this is essential to understanding zinc functions in cellular physiology and pathogenesis. In recent decades, an increasing amount of evidence has uncovered critical roles of a number of proteins in zinc metabolism and homeostasis through influxing, chelating, sequestrating, coordinating, releasing, and effluxing zinc. Metallothioneins (MT) and Zrt- and Irt-like proteins (ZIP) and Zn transporters (ZnT) are the proteins primarily involved in these processes, and their malfunction has been implicated in a number of inherited diseases such as acrodermatitis enteropathica. The present review updates our current understanding of the biological functions of MTs and ZIP and ZnT transporters from several new perspectives.     

X型聚丙烯纤维力学性能试验研究

针对日本生产的X型聚丙烯纤维,采用微机控制电子万能试验机,对其抗拉强度、断裂伸长率、弹性模量等力学指标进行了试验,并与分别经过pH值为12.5的碱溶液和120℃的烘箱处理后的纤维力学性能进行了对比.试验结果表明:① X型聚丙烯纤维拉伸强度高、弹性模量大、延性好;②纤维耐碱、耐热性能好,经碱溶液处理后,纤维拉伸强度、弹性模量和断裂伸长率分别达到处理前的93.8%、96.3%、89.6%;经耐热处理后,纤维拉伸强度、弹性模量和断裂伸长率分别达到处理前的98.7%、99.4%、93.4%.     

Nonlinear dielectric response and positive dielectric tunability in antipolar CaTiSiO5

Dielectric tunability has been extensively investigated in ferroelectric materials, which exhibit a negative tunability of dielectric permittivity in an external electric field. In contrast, positive tunability is rare and has been reported only in a few antiferroelectric materials. We present positive (and negative) tunability in the titanite, CaTiSiO₅. The dielectric property of CaTiSiO₅ was measured up to an extraordinarily high electric field of 40 MV/m. A nonlinear polarization field loop with no hysteresis was obtained. The dielectric permittivity of ε_r ~ 25 increases up to ε_r ~ 40 at 20 MV/m and room temperature. Although titanite has an antipolar structure and is expected to be “antiferroelectric,” its dielectric response in high electric fields up to ~40 MV/m differs from that of conventional antiferroelectrics. We demonstrate that the phase-transition temperature and dielectric tunability could be modulated through the chemical substitution of Ca_1−xLa_xTiSi_1−xAl_xO₅, in which the destabilization of the long-range antipolar order is revealed by transmission electron microscopy analysis. These results indicate that the observed dielectric response to an electric field may originate from the unique features of the antipolar and domain structures in CaTiSiO₅.     

Laser pressure welding of aluminium and galvannealed steel

Dissimilar metal joints of galvannealed steel and commercially available pure aluminium (A1050) sheets were produced by changing the laser power and the roller pressure by the laser pressure welding method. In this method, the YAG laser beam was irradiated into a flare groove made by these dissimilar metal sheets. In addition, the laser beam was scanned at various frequencies and patterns through the fθ lens using two-dimensional scanning mirrors. Then the sheets were pressed by the pressure rolls to be joined. The compound layers in the weld interface were observed by optical microscope, and the layer thicknesses were measured. The thicknesses were in the range of 7–20 μm. The mechanical properties of welded joints were evaluated by the tensile shear test and the peel test. In the tensile shear test, the strengths of the joints produced under the most welding conditions were so high that the fracture occurred through the base aluminium sheet. In the peel test of the specimens subjected to the laser beam of 1200–1400 W power under the roller pressure of 2.94 kN, the specimen fracture took place in the base aluminium sheet. Even if the compound layer was thick, high joint strength was obtained. In order to know the reason for such high strength of joints with thick compound layers and the joining mechanism, the compound layer was observed by the HR-TEM. The TEM observation results revealed that the main phase in the compound layer was the solid solution of Al + Zn. Moreover, the intermetallic compound was identified as FeAl, Fe₂Al₅, Fe₄Al₁₃, and Fe₂Al₅Zn_0.4 phase by electron diffraction. The Fe₃Zn₁₀ (Γ phase) of Fe–Zn intermetallic compound was confirmed on a Fe base material. It is assumed that the joining areas were heated in a range of 782°C more than 665°C, a melting point of Al, by laser irradiation because the δ_lk phase aspect was not confirmed. Because the surfaces of A1050 and Zn plated layer were melted thinly, the layer was over 10 μm thicker. The reason for the production of high strength joints with the relatively thick intermetallic compound layer was attributed to the formation of (Al + Zn) phase with finely dispersed intermetallic compounds.     

HR-TEM observation of laser pressure weld of galvannealed steel and pure aluminium

Laser pressure welding was conducted by changing the laser power and the roller pressure in the previous experiment. It was revealed that dissimilar metal welding of galvannealed steel and pure aluminium was feasible in a wide range of welding conditions. When the roller pressure was more than 1.96 kN at the laser powers equal to or less than 1400 W, the joint strengths were so high that the specimens in the tensile shear and the peel tests fractured in the A1050 parent metal.

In order to know the reason for such high strengths of joints with thick compound layers and the joining mechanism, the compound layer was observed by HR-transmission electron microscopy (TEM). The TEM observation results revealed that the main phase in the compound layer was the solid solution of Al + Zn. Moreover, the intermetallic compound was identified as FeAl, Fe₂Al₅, Fe₄Al₁₃ and Fe₂Al₅Zn_0.4 phase by electron diffraction. The Fe₃Zn₁₀ (Γ phase) of Fe–Zn intermetallic compound was confirmed on a Fe base material. It is guessed that the joining areas were heated at a range of 782°C more than 665°C, a melting point of Al, by laser irradiation because the δ_lk phase aspect was not confirmed. Because the surfaces of A1050 and Zn plated layer were melted thinly, the layer was over 10 μm thicker. The reason for the production of high-strength joints with a relatively thick intermetallic compound layer was attributed to the formation of (Al + Zn) phase with finely dispersed intermetallic compounds.