Modifications of reward expectation-related neuronal activity during learning in primate striatum

This study investigated neuronal activity in the anterior striatum while monkeys repeatedly learned to associate new instruction stimuli with known behavioral reactions and reinforcers. In a delayed go-nogo task with several trial types, an initial picture instructed the animal to execute or withhold a reaching movement and to expect a liquid reward or not. During learning, new instruction pictures were presented, and animals guessed and performed one of the trial types according to a trial-and-error strategy. Learning of a large number of pictures resulted in a learning set in which learning took place in a few trials and correct performance exceeded 80% in the first 60-90 trials. About 200 task-related striatal neurons studied in both familiar and learning conditions showed three forms of changes during learning. Activations related to the preparation and execution of behavioral reactions and the expectation of reward were maintained in many neurons but occurred in inappropriate trial types when behavioral errors were made. The activations became appropriate for individual trial types when the animals' behavior adapted to the new task contingencies. In particular, reward expectation-related activations occurred initially in both rewarded and unrewarded movement trials and became subsequently restricted to rewarded trials. These changes occurred in parallel with the visible adaptation of reward expectations by the animals. The second learning change consisted in decreases of task-related activations that were either restricted to the initial trials of new learning problems or persisted during the subsequent consolidation phase. They probably reflected reductions in the expectation and preparation of upcoming task events, including reward. The third learning change consisted in transient or sustained increases of activations. These might reflect the increased attention accompanying learning and serve to induce synaptic changes underlying the behavioral adaptations. Both decreases and increases often induced changes in the trial selective occurrence of activations. In conclusion, neurons in anterior striatum showed changes related to adaptations or reductions of expectations in new task situations and displayed activations that might serve to induce structural changes during learning.     

High frequency dynamic imaging of domains in thin film heads

A wide-field magnetooptic domain observation system with a time resolution of 10 ns has been developed to study magnetization dynamics in thin-film heads. The instantaneous dynamic response on the top yoke of thin-film recording heads is examined at any chosen instant within the drive current cycle at frequencies up to 20 MHz. Different phase responses from different domain walls in the head are observed and interpreted in terms of hysteretic wall motion, effective field density variation in the head, and wall orientations relative to the flux conduction direction. Two different flux conduction mechanisms associated with two different domain structures in the central region of the head are observed and discussed. Flux conduction in the center of the head by motion of backgap walls and magnetization rotation for domain structures with and without the backgap walls was observed. The domain structure with the backgap walls is probably undesirable because the backgap wall motion may cause a decrease in head efficiency during high-frequency operation and could cause noise during read-back     

The role of ricochet impacts on impact vaporization

Vaporization of carbonate targets by hypervelocity impact increases with decreasing impact angle (from the horizontal), in contrast with expectations based only on peak shock pressures. Experiments at the NASA Ames Vertical Gun Range were designed to allow isolating the underlying controlling processes and probing the vapor composition using high-speed spectroscopy. Vaporization associated with the maximum peak pressures (first contact) was separated from vaporization generated only by downrange ricochet impacts through the use of split targets. Four telescopes isolated the vapor with different velocities and revealed that grazing ricochet debris downrange contributed a significant fraction to the overall vaporization process. These results can be understood by the high temperatures and low pressures created by high strain-rate shear.     

Novel In Situ Nanostructure-Dendrite Composites in Zr-Base Multicomponent Alloy System

The evolution of a nanostructure-dendrite composite microstructure of two Zr-base alloys solidified through different casting routes is presented. The alloys were designed by adding different amounts of Nb to the Zr-based multicomponent glass-forming alloy system. The refractory metal Nb promotes the formation of a primary phase having dendritic morphology, whereas the residual melt solidifies to a nanostructured/amorphous matrix. The volume fraction and the morphology of the dendritic phase varied with the Nb content and the adopted casting route. A correlation between the alloy composition and adopted casting method with evolved microstructures and mechanical properties is revealed. These composites exhibit a unique combination of high fracture strength up to 1922 Mpa, as well as plastic strain over 15.8% under uniaxial compression testing at room temperature. The high strength of these composites is imparted by the nanostructured matrix, whereas the large plastic strain is a consequence of the retardation of excessive localized shear banding in the matrix by ductile dendrites. The significant work hardening of the composites prior to fracture is attributed to dislocation multiplication in the solid solution-strengthened dendritic phase.     

Effect of Orientation and Organization of Polymers at Interfaces on Adhesive Strength

To gain a better understanding of polymer adhesion, one must take into account the phenomena of orientation and organization of macromolecules at interfaces which can lead to the creation of interphases. The formation of such interphases involves chemical, physicochemical and physical mechanisms which are illustrated by examples taken from our recent work dealing mainly with adhesive assemblies and composite materials.