The carcinogenic effect of 5-bromodeoxyuridine and its amplification by x-rays in rats

5-bromodeoxyuridine (BUdR) injected to rats in the neonatal period is shown to produce a pronounced carcinogenic effect which brings about the appearance of various benign and malignant tumours. Exposure of females to X-ray total-body irradiation (1.5 Gy) was followed by intensification of the carcinogenic effect of BUdR. Assuming that this pyrimidine analog reacts solely with DNA substituting thymidine during DNA synthesis and induces point mutations due to tautomerization, the data obtained demonstrate the possibility of tumour induction by a selective DNA perturbation.     

Change in physicomechanical properties of steel D1604AT15 during fatigue at different loading frequencies

Results are presented in a statistical arrangement for studying the effect of loading frequency on the fatigue life in bending of plates with a stress concentrator. The nature of change in microhardness, electrical conductivity, dislocation density, and block dimensions during fatigue at frequencies of 2.8, 8.8, and 18 kHz has been demonstrated. It has been established that in spite of some qualitative difference the main indicators of fatigue at these frequencies are retained.S. M. Kirov Belorussian Technology Institute, Minsk. Translated from Problemy Prochnosti, No. 10, pp. 31–34, October, 1989.     

Dewatering of liwuid radioactive wastes in thin-film rotary evaporators

Translated from Atomnaya Énergiya, Vol. 67, No. 1, pp. 11–15, July, 1989.