On-Chip Optical Technology in Future Bus-Based Multicore Designs

This work investigates the integration of CMOS-compatible optical technology to on-chip coherent buses for future CMPs. The analysis results in a hierarchical optoelectrical bus that exploits the advantages of optical technology while abiding by projected limitations. This bus achieves significant performance improvement for high-bandwidth applications relative to a state-of-the-art fully electrical bus     

Recognizing, assessing, and intervening with problems of professional competence.

Working collaboratively, psychologist educators and trainers at the doctoral, internship, and postdoctoral levels; credentialers; practitioners; and students offer 8 proposals for psychologists to consider in recognizing, assessing, and intervening with problems of professional competence in students and practicing professionals. In the proposals, the authors address the following topics: definitions and categories; preparing the system; self-assessment; remediation; diversity; communication across various levels of the system; confidentiality; and ethical, regulatory, and legal underpinnings. They also propose future directions for the assessment of problems in professional competence in both students and practicing psychologists. (PsycINFO Database Record (c) 2010 APA, all rights reserved)     

General relativity and quantum mechanics: towards a generalization of the Lambert W function A Generalization of the Lambert W Function

We present a canonical form for a natural and necessary generalization of the Lambert W function, natural in that it requires minimal mathematical definitions for this generalization, and necessary in that it provides a means of expressing solutions to a number of physical problems of fundamental nature. This generalization expresses the exact solutions for general-relativistic self-gravitating N-body systems in one spatial and one time dimension, and a previously unknown mathematical link between the (1+1) gravity problem and the Schrödinger wave equation.     

Role of adenine nucleotides in the activation of microsomal cholesterol ester hydrolase by fructose or adenosine in rat hepatocytes

The significance of the demonstration of a clonal B-cell population in gastric lymphoid infiltrates was investigated by analysis of immunoglobulin heavy chain (IgH) gene rearrangements using sensitive polymerase chain reactions, employing fluorescently labelled primers to target the FR3 and FR1 regions. Tissue blocks were studied showing different histological features (high-grade lymphoma, low-grade lymphoma, and chronic gastritis) from 12 gastrectomies for primary gastric lymphoma, together with blocks showing chronic gastritis from 13 cases of gastric adenocarcinoma and biopsies from 33 patients with active Helicobacter-associated chronic gastritis. Clonal IgH gene rearrangements were detected in lymphoma samples from eight of the gastrectomies for lymphoma (67 per cent). In four of these eight specimens, clonal rearrangements were also detectable in the samples showing only chronic gastritis. Three of 28 (11 per cent) informative biopsies showing active Helicobacter-associated chronic gastritis had detectable clonal populations. Clonal rearrangements were also demonstrated in two of eight (25 per cent) informative blocks showing chronic gastritis from eight gastrectomies for adenocarcinoma. It is concluded that the detection of a clonal population in a suspicious lymphoid infiltrate does not confirm the diagnosis of lymphoma, nor does the absence of such a population imply benignity.     

Mapping of Trellises Associated with General Encoders onto High-Performance VLSI Architectures

A rate 1/n binary generic convolutional encoder is a shift-register circuit where the inputs are information bits and the outputs are blocks of n bits generated as linear combinations on the appropriate shift register contents. The decoding of the outputs of a convolutional encoder can be carried out by the well-known Viterbi algorithm. The communication pattern of the Viterbi Algorithm is given as a graph, called trellis, associated to the state diagram of the corresponding encoder. In this paper we present a methodology that permits the efficient mapping of the Viterbi algorithm onto a column of an arbitrary number of processors. This is done through the representation of the data flow by using mathematical operators which present an inmediate hardware projection. A single operator string has been obtained to represent a generic encoder through the study of the data flow of free-forward encoders and feed-back encoders. The formal model developed is employed for the partitioning of the computations among an arbitrary number of processors in such a way that the data are recirculated opimizing the use of the processors and the communications. As a result, we obtain a highly regular and modular architecture suitable for VLSI implementation.     

Isolation and DNA sequence of the STE14 gene encoding farnesyl cysteine: Carboxyl methyltransferase

We isolated a mutant defective in C-terminal farnesyl cysteine:carboxyl methyltransferase activity from a screen for mutations causing a -specific sterility. A genomic fragment was cloned from a yeast multi-copy library that restored mating. Both the cloned gene and the sterile mutation were allelic to the STE14 gene. A ste14-complementing 2·17 kb BamHI fragment subclone was sequenced and found to encode a 239 amino acid protein with a molecular weight of 27,887 Daltons. The hydrophobicity profile of the methyltransferase reveals the presence of at least five potential transmembrane domains. In comparisons of the C-terminal methyltransferase amino acid sequence with those in the PIR and Swiss protein databases, no significantly similar sequences were found nor were conserved regions from other methyltransferases present.     

Scene Graph and Frame Update Algorithms for Smooth and Scalable 3D Visualization of Simulated Construction Operations

One of the prime reasons inhibiting the widespread use of discrete-event simulation in construction planning is the absence of appropriate visual communication tools. Visualizing modeled operations in 3D is arguably the best form of communicating the logic and the inner working of simulation models and can be of immense help in establishing the credibility of analyses. New software development technologies emerge at incredible rates that allow engineers and scientists to create novel, domain-specific applications. The authors capitalized on a computer graphics technology based on the concept of the scene graph to design and implement a general-purpose 3D visualization system that is simulation and CAD-software independent. This system, the Dynamic Construction Visualizer, enables realistic visualization of modeled construction operations and the resulting products and can be used in conjunction with a wide variety of simulation tools. This paper describes the scene graph architecture and the frame updating algorithms used in designing the Dynamic Construction Visualizer.     

Railgun performance with a two-stage light-gas gun injector

Results obtained with the HELEOS (hypervelocity experimental launcher for equation of state) railgun, which uses a two-stage light-gas gun (2SLGG) as an injector, are presented. The high-velocity 2SLGG injector preaccelerates projectiles up to ~7 km/s. The high injection velocity reduces the exposure duration of the railgun barrel to the passing high temperature plasma armature, thereby reducing the ablation and subsequent armature growth. The 2SLGG also provides a column of cool, high-pressure hydrogen gas to insulate the rails behind the projectile, thereby eliminating restrike. A means to form an armature behind the injected projectile has been developed. In preliminary tests, the third-stage railgun has successfully increased the projectile velocity by 1.35 km/s. Extensive diagnostics have been used to determine the behavior of the armature and track the launcher's performance. Insome cases, velocity increases in the railgun section have been achieved, which are in close agreement with theoretical predictions, whereas in other experiments deviations from theoretical have been observed. The reasons for and implications of these results are addressed. Recent tests are reported