Ru/SiO2 Catalyst for Highly Selective Hydrogenation of Dimethyl Malate to 1,2,4-Butanetriol at Low Temperatures in Aqueous Solvent

Catalysis Letters - Catalytic selective hydrogenation of esterified malic acid to produce 1,2,4-butanetriol (1,2,4-BT) using H2 as the reducing reagent suffers from the low 1,2,4-BT selectivity....     

Catalyst-Controlled Selectivity in Oxidation of Olefins: Highly Facile Success to Functionalized Aldehydes and Ketones

Catalysis Letters - The attractive challenge in green chemistry is exploring novel heterogeneous catalyst system for catalyst-controlled product selectivity for oxidation of olefins. Hence, we...     

Correlation of Vibroacoustic Signal with Ceramic Component Wear During Frictional Interaction with a Steel Disc

Refractories and Industrial Ceramics - Complete correlation between dimensions of the wear area on specimens made of oxide-carbide ceramics and the root-mean-square value of vibration acceleration...     

About the Nature of Quasi-Cleavage in Low-Carbon Steel Embrittled with Hydrogen

Metal Science and Heat Treatment - Scanning electron microscopy and confocal laser scanning microscopy are used to study a fracture surface of hydrogen-charged low-carbon steel, which has been...     

Experimental Search for Chemical Compositions of Superelastic Titanium Alloys with Enhanced Functional Properties

Metal Science and Heat Treatment - Ti – Zr-based alloys with a high zirconium content prepared by vacuum-arc remelting with nonconsumable tungsten electrode are studied. The optimum number of...     

Simulation of the Kinetics of Dynamic Recrystallization of Alloy KhN55MBYu-VD During Hot Deformation

Metal Science and Heat Treatment - A facility for physical simulation is used to plot dependences of flow stress on the degree of deformation in the temperature range from 1000 to 1230°C at...     

As-cast microstructure of Al-Zn-Mg-Cu-Zr alloy containing trace amount of Sc

It has been reported that the element scandium(Sc) is the most effective modificator which can significantly refine the grain size, prohibit recrystallization process and increase the strength. Adding trace of Sc in 7000 series aluminum alloys is considered to be an effective way to modify its micros tructure and promote mechanical properties. In order to study the effect of Sc element on ascast microstructure of Al-Zn-Mg-Cu-Zr alloy, ingots containing different amounts of Sc were prepared by ferrous-mold cast. Microstructures were characterized by means of differential scanning calorimeter(DSC), X-ray diffraction(XRD), optical microscope(OM) and scanning electrical microscope(SEM). The results indicate that when the Sc level exceeds a critical concentration,Al_3(Sc,Zr) primary phase would form in the melt and act as an efficient nucleant, resulting in very refined grain and an equiaxed grain structure. Sc element reduces the number of eutectic phases formed during solidification,coupled with an increase in the concentration of major alloying elements retained in the solute. This behavior suggests possible benefits in improving the integrated properties of terminal products.     

Kinetics of the hydrotreatment of rapeseed oil fatty acid triglycerides under mild conditions

To establish principal regularities of the hydrotreatment of rapeseed oil fatty acid triglycerides (FATs), the kinetics of this process has been studied at temperatures of 300–380°C, contact times of 0.38–0.10 h, and a hydrogen pressure of 1.0 MPa in a flow fixed-bed reactor. The process is performed over nonsulfided nickel catalysts, which are of great practical interest for the production of green diesel. The kinetic scheme of the process with consideration for target products (alkanes) and all oxygen-containing by-products has been proposed. The quantitative estimate, which enables the prediction of the composition of products for other process conditions, has been obtained for the principal paths of the hydrotreatment of rapeseed oil FATs.     

Linear Aliphatic Dialkynes as Alternative Linkers for Double‐Click Stapling of p53‐Derived Peptides

We investigated linear aliphatic dialkynes as a new structural class of i,i+7 linkers for the double‐click stapling of p53‐based peptides. The optimal combination of azido amino acids and dialkynyl linker length for MDM2 binding was determined. In a direct comparison between aliphatic and aromatic staple scaffolds, the aliphatic staples resulted in superior binding to MDM2 in vitro and superior p53‐activating capability in cells when using a diazidopeptide derived from phage display. This work demonstrates that the nature of the staple scaffold is an important factor that can affect peptide bioactivity in cells.