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排序方式： 共有498条查询结果，搜索用时 15 毫秒
51.
52.
Syed Waqar Haider Wouter C. Brink Neeraj Buch 《International Journal of Pavement Engineering》2017,18(7):645-657
The performance prediction models in the Pavement-ME design software are nationally calibrated using in-service pavement material properties, pavement structure, climate and truck loadings, and performance data obtained from the Long-Term Pavement Performance programme. The nationally calibrated models may not perform well if the inputs and performance data used to calibrate those do not represent the local design and construction practices. Therefore, before implementing the new M-E design procedure, each state highway agency (SHA) should evaluate how well the nationally calibrated performance models predict the measured field performance. The local calibrations of the Pavement-ME performance models are recommended to improve the performance prediction capabilities to reflect the unique conditions and design practices. During the local calibration process, the traditional calibration techniques (split sampling) may not necessarily provide adequate results when limited number of pavement sections are available. Consequently, there is a need to employ statistical and resampling methodologies that are more efficient and robust for model calibrations given the data related challenges encountered by SHAs. The main objectives of the paper are to demonstrate the local calibration of rigid pavement performance models and compare the calibration results based on different resampling techniques. The bootstrap is a non-parametric and robust resampling technique for estimating standard errors and confidence intervals of a statistic. The main advantage of bootstrapping is that model parameters estimation is possible without making distribution assumptions. This paper presents the use of bootstrapping and jackknifing to locally calibrate the transverse cracking and IRI performance models for newly constructed and rehabilitated rigid pavements. The results of the calibration show that the standard error of estimate and bias are lower compared to the traditional sampling methods. In addition, the validation statistics are similar to that of the locally calibrated model, especially for the IRI model, which indicates robustness of the local model coefficients. 相似文献
53.
Anat Akiva Johanna Melke Sana Ansari Nalan Liv Robin van der Meijden Merijn van Erp Feihu Zhao Merula Stout Wouter H. Nijhuis Cilia de Heus Claudia Muñiz Ortera Job Fermie Judith Klumperman Keita Ito Nico Sommerdijk Sandra Hofmann 《Advanced functional materials》2021,31(17):2010524
Bone formation (osteogenesis) is a complex process in which cellular differentiation and the generation of a mineralized organic matrix are synchronized to produce a hybrid hierarchical architecture. To study the mechanisms of osteogenesis in health and disease, there is a great need for functional model systems that capture in parallel, both cellular and matrix formation processes. Stem cell-based organoids are promising as functional, self-organizing 3D in vitro models for studying the physiology and pathology of various tissues. However, for human bone, no such functional model system is yet available. This study reports the in vitro differentiation of human bone marrow stromal cells into a functional 3D self-organizing co-culture of osteoblasts and osteocytes, creating an organoid for early stage bone (woven bone) formation. It demonstrates the formation of an organoid where osteocytes are embedded within the collagen matrix that is produced by the osteoblasts and mineralized under biological control. Alike in in vivo osteocytes, the embedded osteocytes show network formation and communication via expression of sclerostin. The current system forms the most complete 3D living in vitro model system to investigate osteogenesis, both in physiological and pathological situations, as well as under the influence of external triggers (mechanical stimulation, drug administration). 相似文献
54.
Wouter N. Wermink Dmitri Spinu Geert F. Versteeg 《Chemical Engineering Communications》2019,206(4):454-475
The oxidation of ferrous ions in acidic sulfate solutions in the presence of cupric ions at elevated air pressures was investigated in a high-intensity gas–liquid contactor. The study was required for the design of the regeneration steps of the novel Vitrisol® desulphurization process. The effects of the Fe2+ concentration, Cu2+ concentration, Fe3+ concentration, initial H2SO4 concentration, and partial oxygen pressure on the reaction rate were determined at three different temperatures, i.e., T?=?50?°C, 70?°C, and 90?°C. Most of the experiments were determined to be affected by the mass transfer of oxygen, and therefore true intrinsic kinetics could not be fully determined. An increase in Fe2+ and Cu2+ concentrations, as well as the partial pressure of oxygen and temperature, increased the Fe2+ oxidation rate. H2SO4 did not influence the Fe2+ oxidation rate. An increase in Fe3+ concentration decreased the Fe2+ oxidation rate. Although determined from experiments partially affected by mass transfer, a first order of reaction in Fe2+ was observed, fractional orders in both Cu2+ and O2 were measured, a zero order in H2SO4 was determined, and a negative, fractional order in Fe3+ was obtained. The activation energy was estimated to be 31.3?kJ/mol. 相似文献
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56.
ABSTRACTGiven that online platforms disrupt established industries and challenge existing institutions, they can only be successful if their innovation becomes both legal and legitimate. This requires ‘institutional work’ that changes perceptions and regulations within society. Rather than only focussing on the online platform as the sole agent engaging in institutional work, our study analyses institutional work as a collective process. We investigate the case of home-sharing platform Airbnb and the process of institutional change its introduction prompted regarding short-term rental in Amsterdam, London and New York. We find, contrary to the popular view of online platforms as disruptive entrepreneurs, that the platform mainly focusses on creating new institutions rather than disrupting existing ones, and that users and non-users undertake most of the institutional work activities. We also show that different types of actors carry out different types of institutional work suggesting that the process of institutional work is highly distributed. 相似文献
57.
Paula Perez‐Rodriguez Wouter Vijselaar Jurriaan Huskens Machiel Stam Michael Falkenberg Miro Zeman Wilson Smith Arno H.M. Smets 《Progress in Photovoltaics: Research and Applications》2019,27(3):245-254
Solar fuels are a promising way to store solar energy seasonally. This paper proposes an earth‐abundant heterostructure to split water using a photovoltaic‐electrochemical device (PV‐EC). The heterostructure is based on a hybrid architecture of a thin‐film (TF) silicon tandem on top of a c‐Si wafer (W) heterojunction solar cell (a‐Si:H (TF)/nc‐Si:H (TF)/c‐Si(W)) The multijunction approach allows to reach enough photovoltage for water splitting, while maximizing the spectrum utilization. However, this unique approach also poses challenges, including the design of effective tunneling recombination junctions (TRJ) and the light management of the cell. Regarding the TRJs, the solar cell performance is improved by increasing the n‐layer doping of the middle cell. The light management can be improved by using hydrogenated indium oxide (IOH) as transparent conductive oxide (TCO). Finally, other light management techniques such as substrate texturing or absorber bandgap engineering were applied to enhance the current density. A correlation was observed between improvements in light management by conventional surface texturing and a reduced nc‐Si:H absorber material quality. The final cell developed in this work is a flat structure, using a top absorber layer consisting of a high bandgap a‐Si:H. This triple junction cell achieved a PV efficiency of 10.57%, with a fill factor of 0.60, an open‐circuit voltage of 2.03 V and a short‐circuit current density of 8.65 mA/cm2. When this cell was connected to an IrOx/Pt electrolyser, a stable solar‐to‐hydrogen (STH) efficiency of 8.3% was achieved and maintained for 10 hours. 相似文献
58.
Joalet Dalene Steenkamp Wouter Gideon Bam Sello Peter Tsebe 《JOM Journal of the Minerals, Metals and Materials Society》2018,70(11):2422-2427
Benchmarking is a tool available to furnace operators to evaluate their tap-hole life-cycle management practices against those of their peers. It allows furnace operators to challenge their own practices in order to increase furnace utilization. To facilitate the benchmarking process, it is necessary to define the variables to be considered and how they relate to one another. This article develops, from the literature and industry interviews, a holistic conceptualization of the variables that form part of tap-hole lifecycle management and performance. Specifically, the article focuses on the variables related to coke-bed-based processes (FeCr, SiMn, and HCFeMn) applying SAF technology of circular design. 相似文献
59.
The removal of natural organic matter (NOM) using nanofiltration (NF) is increasingly becoming an option for drinking water treatment. Low molecular weight (LMW) organic compounds are nevertheless only partially retained by such membranes. Bacterial regrowth and biofilm formation in the drinking water distribution system is favoured by the presence of such compounds, which in this context are considered as the assimilable organic carbon (AOC). In this study, the question of whether NF produces microbiologically stable water was addressed. Two NF membranes (cut-off of about 300 Da) were tested with different natural and synthetic water samples in a cross-flow filtration unit. NOM was characterised by liquid chromatography with organic carbon detection (LC-OCD) using a size-exclusion column in addition to specific organic acid measurements, while AOC was measured in a batch growth bioassay.Similarly to high molecular weight organic compounds like polysaccharides or humic substances that have a permeability lower than 1%, charged LMW organic compounds were efficiently retained by the NF membranes tested and showed a permeability lower than 3%. However, LMW neutrals and hydrophobic organic compounds permeate to a higher extent through the membranes and have a permeability of up to 6% and 12%, respectively. Furthermore, AOC was poorly retained by NF and the apparent AOC concentration measured in the permeated water was above the proposed limit for microbiologically stable water. This indicates that the drinking water produced by NF might be biologically unstable in the distribution system. Nevertheless, in comparison with the raw water, NF significantly reduced the AOC concentration. 相似文献
60.