Protein interaction networks: centrality,modularity, dynamics,and applications

In the post-genomic era, proteomics has achieved significant theoretical and practical advances with the development of high-throughput technologies. Especially the rapid accumulation of protein-protein interactions (PPIs) provides a foundation for constructing protein interaction networks (PINs), which can furnish a new perspective for understanding cellular organizations, processes, and functions at network level. In this paper, we present a comprehensive survey on three main characteristics of PINs: centrality, modularity, and dynamics. 1) Different centrality measures, which are used to calculate the importance of proteins, are summarized based on the structural characteristics of PINs or on the basis of its integrated biological information; 2) Different modularity definitions and various clustering algorithms for predicting protein complexes or identifying functional modules are introduced; 3) The dynamics of proteins, PPIs and sub-networks are discussed, respectively. Finally, the main applications of PINs in the complex diseases are reviewed, and the challenges and future research directions are also discussed.     

Dynamic buffering performance of the honeycomb paperboard filled with polyurethane

A new kind of composite buffering material was made by filling the voids of honeycomb paperboard with polyurethane. Drop tests were performed to evaluate the dynamic energy absorption capacity of the material. Based on the tests results, we analyzed the mechanical behaviors of the material under different conditions and obtained the inherent influencing laws of some factors on the material＇s dynamic buffering performance. It was shown that the dynamic buffering performance varied directly with impact velocity, and inversely with the void diameter, thickness and buffeting area of the composite material.     

安徽中小企业发展现状及创新路径研究

近几年,在政府大力扶持之下,安徽中小企业快速发展,已成为推动经济持续、健康发展的重要力量,但在发展过程中也存在一些不容忽视的问题。本文从企业总量、地区分布、企业产值、所有制类型等方面对安徽中小企业进行调查,在此基础上分析安徽中小企业在发展过程中存在的问题,并提出相应的建议和对策,对丰富中小企业发展理论、制定安徽中小企业发展政策具有一定的意义。     

Engineering all-aromatic polyamide surface from hydrophilic to superhydrophobic and the accelerated strategy

Being a new kind of nanomaterials, aromatic polyamide nanofibers (ANF) have been much highlighted in recent studies. We here demonstrate an isopropyl alcohol (IPA) accelerated chemical cleavage on poly (p-phenylene terephthalamide) chopped fibers, which provides an efficient preparation method of ANF. The comprehensive study on the processes accelerated by different alcohols revealed that the preparation time of ANF in the mixed medium of dimethyl sulfoxide (DMSO)-alcohol (20:1 in volume) was shorten to 45 min and 75 min for methanol (ethanol) and isopropanol, respectively. However, the nanofibers prepared in DMSO-IPA exhibited the minimum in axial and radial dimensions, providing the finest and most uniform diameter of 16 nm. The corresponding ANF films through vacuum assisted filtration also showed the highest tensile strength of 150 MPa, in comparison with those of the ANF films prepared using other alcohols, which were about 110 MPa. Furthermore, ANF/silicon hybrid films were prepared by the ionic ring-opening reaction followed by the alkoxysilane condensation and nanoparticle fabrication. By changing the organo functional groups in the alkoxysilane, the surface of the films were adjustable in a wide contact angle range from 56° (hydrophilic) to 150° (superhydrophobic), suggesting the amendable interfacial properties potential applicable to composite fabrication with most of the resin matrix.     

硝硫混酸与Ag、Cu反应的动力学

用失重法探讨了硝硫混酸此例、浸出温度和时间等因素对银的溶解和铜的钝化的影响。结果表明:在一定的[HNO_3]范周内,较高温度时,银的溶解符合一级反应规律;求得银的溶解量与时间、HNO_3起始浓度等的关系式和相应的反应活化能;铜在此条件时是钝化的。本实验再一次证实了银的溶解和铜的钝化机理的正确性,也为银、铜的分离提供了实验依据。     

移动定位技术的现状与发展趋势

基于位置服务为人们的日常生活带来了极大的方便,同时也推动了移动定位技术行业的快速发展。针对移动定位技术发展状况,分析目前主流定位技术的优劣,并对取得的突破作简单的总结归纳。     

公交车的远卡自动收费系统设计

在对公交收费系统的发展和无线射频识别技术进行研究的基础上,分析了现行公交收费系统的优缺点与局限性,并提出了一种公交车远卡自动收费系统的设计思路.主要使用ARM核芯片STM32、射频芯片nRF24LE1等器件,完成了硬件设计.在软件设计上实现了自动计算票价的扣费机制.该系统创新性地将远距离射频技术应用在公交收费系统中,不仅方便了乘客,而且大大提高了乘客上下车的效率.     

Parallel XPath query based on cost optimization

The Journal of Supercomputing - The performance of XPath query is the key factor to the capacity of XML processing. It is an important way to improve the performance of XPath by making full use of...