NMR Characterization of Long-Chain Fatty Acylcarnitine Binding to the Mitochondrial Carnitine/Acylcarnitine Carrier

The mitochondrial carnitine/acylcarnitine carrier (CAC) transports short-, medium- and long-carbon chain acylcarnitines across the mitochondrial inner membrane in exchange for carnitine. How CAC recognizes the substrates with various fatty acyl groups, especially long-chain fatty acyl groups, remains unclear. Here, using nuclear magnetic resonance (NMR) technology, we have shown that the CAC protein reconstituted into a micelle system exhibits a typical six transmembrane structure of the mitochondrial carrier family. The chemical shift perturbation patterns of different fatty acylcarnitines suggested that the segment A76–G81 in CAC specifically responds to the long-chain fatty acylcarnitine. Molecular dynamics (MD) simulations of palmitoyl-L-carnitine inside the CAC channel showed the respective interaction and motion of the long-chain acylcarnitine in CAC at the cytosol-open state and matrix-open state. Our data provided a molecular-based understanding of CAC structure and transport mechanism.     

空冷岛内部流场的建模分析和试验对比

空冷岛作为一个空冷电厂的大型换热器,其性能与内外流场密切相关。对空冷岛内部流场进行了系统建模分析,并结合试验进行对比,对空冷岛内部流场的分布规律有了较为深入的理解,为进一步的优化提供了基础。给出了对应于试验结果的空冷岛凝结温度分布的原因及凝结压力分布、凝结流量分配计算结果。     

Analysis on the Latest Assessment Criteria of ASME B31G-2009 for the Remaining Strength of Corroded Pipelines

ASME B31G provides the most basic and widespread method in assessing the remaining strength of corroded pipelines. The third edition B31G (ASME B31G-2009) is the latest revision issued by the American National Standards Institute (ANSI) and is used as the basis for this study. This article discusses the development process of ASME B31G, and presents the comparative analysis of ASME B31G, RSTRENG, and DNV RP-F101. The predicted failure pressures are calculated by each standard mentioned above, based on 35 groups of data for full-size pipe tests collected from the literature. The deviations between the predicted values and the actual experiment results are discussed. Finally, practical applications are compared among the assessment methods. The investigation showed that predictions based on ASME B31G-2009 are much more accurate than predictions based on the previous editions of B31G. The applications of ASME B31G-2009 and RSTRENG 0.85 dL effectively improve the pipe’s conveying efficiency and optimize the cost of managing the piping system. However, they both are applicable only for evaluating the medium- and low-strength pipe steels. In contrast, DNV RP-F101 is applicable to the medium- and high-strength pipe steels, but its results are often not safe for application to the lower-strength pipe steels.     

1310nm大功率高偏振度量子阱超辐射发光二极管

设计并制备了一种斜条脊波导结构压应变高偏振度多量子阱超辐射发光二极管.设计的脊波导出光面TiO2/SiO2四层宽带增透膜的TE模式反射率约为10-6,分析了脊波导角度偏差和膜层厚度偏差对增透膜反射率的影响.实验结果表明,在250 mA直流电流驱动下,所设计的超辐射发光二极管芯片单管输出功率可达22.7 mW,出射光谱FWHM约为37.3 nm,光谱纹波系数低于0.15 dB,TE模式输出光强占主导,偏振度约为19.2 dB.     

基于峰宽修正的玻璃药瓶内氧气残留浓度的检测研究

玻璃药瓶中的氧气残留对瓶中药品的无菌特性造成了严重的威胁。采用波长调制光谱（Wavelength Modulated Spectrum, WMS）技术解调得到的二次谐波信号峰高值作为氧浓度反演的基础。然而,在用二次谐波信号测量气体浓度时,由于调制深度的变化会导致二次谐波峰值的变化,这通常会给系统带来误差,进而降低浓度的反演精度。而调制深度受调制电流波动、温度和压强变化等因素的影响不能直接计算获得进而修正。针对这一问题,本文成功地将调制深度与二次谐波峰高的关系转换为二次谐波峰宽和峰高的关系。然后,利用峰宽校正后的谐波峰高对气体浓度进行反演。初步实验表明,利用峰宽校正后的谐波峰高对瓶内气体浓度进行预测的准确性提高了2.1%,且系统的整体鲁棒性也得以提升。本文提出的校正方法不需要系统参数信息与气体成分信息,可以直接从谐波信号本身出发对调制深度进行校正,十分适合于工业现场的在线氧气浓度预测。     

基于模糊控制的有源滤波器直流母线电压控制

针对传统直流侧电压控制方法存在超调量和静差较大的问题,设计了混合有源电力滤波器控制系统,建立了混合有源电力滤波器的系统模型,并针对直流侧电压控制设计了一套双模糊控制器,与传统直流侧电压控制方法相比,该控制方法具有超调小、响应速度快、静差较小的特点。仿真结果验证了该方法的正确性和可行性。     

无人直升机在民用行业的应用与发展

无人直升机关键技术的突破加快了其在民用行业的应用和普及,结合无人直升机的独特优势详细分析了其在关键民用领域的重点应用,对我国民用无人直升机的发展现状和未来趋势做了论述和展望。     

一种机载超宽带相控阵雷达T/R组件设计

针对机载有源相控阵雷达小型化、多功能、高功率的要求,研制了一款应用于C、X、Ku波段的双通道超宽带T/R砖块组件,外观尺寸为30.0 mm×70.0 mm×8.5 mm.组件在工作频带内可以实现6位移相、6位衰减,工作带宽达到12 GHz,发射输出功率≥ 37 dBm,接收增益达到22 dB.通过对电路中无源结构进行仿真,并利用得到的仿真结果和射频芯片实现链路仿真,解决了超宽带T/R组件端口驻波较差和接收增益平坦度差且难以预估的难题.最终制造的T/R组件具有超宽带、低噪声、高功率以及良好的幅相性能.     

毫米波MIMO发射机中的低复杂度动态子阵列组合方法

对于采用部分连接架构的毫米波MIMO系统,为了提升频谱效率,根据信道条件动态调整各子阵列的天线组成。然而,对天线进行最佳分组需要按照一定准则对所有可能的天线组合进行穷举搜索,将导致复杂度难以接受。针对这一问题,提出了一种低复杂度的子阵列动态分配方法,核心是在对阵元进行分组时,引入一定的规则,从而显著降低组合个数,减少搜索范围。具体而言,给出了两种低复杂度的天线组合算法。首先,考虑到毫米波天线间具有较强的相关性,将相邻多个天线虚拟为一个阵元,从而降低搜索空间。其次,通过将所有天线分为上下半区,实现基于分区的天线组合,实现了搜索空间的降低。仿真结果表明,所提的方法能够在性能和复杂度之间获得较好的折中。